As a straight solvent, d-limonene can replace many types of products such as fluorinated and chlorinated organic solvents, acetone, MEK (methyl ethyl ketone), mineral spirits, glycol ethers, and toluene. Since it is not water soluble, it can be used in typical water separation units. Straight d-limonene can be used in spray systems, as a wipe cleaner, in a dip bath and is a direct substitute for most other organic solvents.

Adhesive Remover, Asbestos shingle remover, Bathroom cleaner, Car wash, Carpet stain cleaner, Concrete cleaner (used in warehouse floor scrubbers or for cleaning oils and greases off concrete pads and parking structures), Cosmetic applications, Electronics cleaning, engine degreaser (automotive, aircraft, and aerospace industries), Floor cleaner, Fragrance additive, Graffiti remover, Grease trap maintainer, Hand cleaner, Heat transfer medium, Industrial odor control applications, Kitchen cleaner, Laundry pre-spotter, Lift station and sewage treatment applications, Marine vessel cleaner, Metal cleaner (industrial), Parts cleaner, Printing press cleaner, Recycling applications, Tar/asphalt remover, Tile remover, Wheel cleaner, Window cleaner. d'Limonene is also a possible candidate for a variety of medical applications including cancer and Aids research, and has been been noted to have insecticidal properties.