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D-mannose is used to treat a rare disease called carbohydrate-deficient glycoprotein syndrome type 1b. This disease is passed down through families. It makes you lose protein through the intestines.
D-mannose may be effective as a treatment for an acute UTI caused by E. coli. D-mannose may effectively relieve acute UTI symptoms caused by type 1 fimbriae-positive bacteria.
There is no standard dosage for D-mannose for UTIs. Studies on oral D-mannose to help prevent UTI have used amounts as varied as 420 milligrams to 2 grams a day, and some studies suggest taking D-mannose more than once a day.