INDOLE AR For estamination of DNA

Substance / Preparation : Indole CAS No :120-72-9

Substance.

Contains no other components or impurities which will influence the classification of the

product.

3.1. Classification of the substance or mixture

Classification EC 67/548 or EC 1999/45

Classification : Xn; R21/22

Xi; R37/38-41

N; R50-53

Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Health hazards : Specific Target Organ Toxicity - Single exposure - Respiratory tract

irritation - Category 3 - Warning (CLP : STOT SE 3) H335

Acute toxicity, Oral - Category 4 - Warning (CLP : Acute Tox. 4) H302

Acute toxicity, dermal - Category 4 - Warning (CLP : Acute Tox. 4) H312

Serious eye damage - Category 1 - Danger (CLP : Eye Dam. 1) H318

Skin irritation - Category 2 - Warning (CLP : Skin Corr. 2) H315

Environmental hazards : Hazardous to the aquatic environment - Acute hazard -

Category 1 - Warning (CLP : Aquatic Acute 1) H400

Hazardous to the aquatic environment - Chronic hazard - Category 1 - Warning (

CLP : Aquatic Chronic 1) H410

3.2. Label elements

Labelling EC 67/548 or EC 1999/45

Symbol(s) : Xn : Harmful

N : Dangerous for the environment

R Phrase(s) : R21/22 : Harmful in contact with skin and if swallowed.

R37/38 : Irritating to respiratory system and skin.

R41 : Risk of serious damage to eyes.

R50/53 : Very toxic to aquatic organisms, may cause long-term adverse effects in

the aquatic environment.

S Phrase(s) : S26 : In case of contact with eyes, rinse immediately with plenty of water

and seek medical advice.

S36/37/39 : Wear suitable protective clothing, gloves and eye/face protection.

S60 : This material and its container must be disposed of as hazardous waste.

S61 : Avoid release to the environment. Refer to special instructions/Safety data sheets.

Labelling Regulation EC 1272/2008 (CLP)

Hazard pictograms

Signal words : Danger

Hazard statements : H318 : Causes serious eye damage.

H302 : Harmful if swallowed.

H312 : Harmful in contact with skin.

H315 : Causes skin irritation.

H335 : May cause respiratory irritation.

H410 : Very toxic to aquatic life with long lasting effects.

Precautionary statements

• Prevention : P280: Wear protective gloves, protective clothing, eye protection, face

protection.

P271: Use only outdoors or in a well-ventilated area.

P261: Avoid breathing dust, fume, gas, mist, vapours, spray.

P273: Avoid release to the environment.

P264: Wash thoroughly after handling.

P270: Do not eat, drink or smoke when using this product.

• Response : P302+P352: IF ON SKIN : Wash with plenty of soap and water.

P301+P312: IF SWALLOWED : Call a POISON CENTER or doctor if you feel unwell.

P332+P313: If skin irritation occurs : Get medical advice.

P391: Collect spillage.

P305+P351+P338: IF IN EYES : Rinse cautiously with water for several minutes.

Remove contact lenses, if present and easy to do. Continue rinsing.

P304+P340: IF INHALED : Remove to fresh air and keep at rest in a position

comfortable for breathing.

P363: Wash contaminated clothing before reuse.

• Storage : P403+P233: Store in well-ventilated place. Keep container tightly closed.

P405: Store locked up.

• Disposal considerations : P501: Dispose of this material and its container to hazardous

or special waste collection point, in accordance with local, regional, national and/or

international regulation.

3.3. Other hazards

Other hazards : The substance does not fulfil the criteria to be identified as PBT

substance or vPvB substance according to Annex XIII of Regulation REACH.

4.1. Description of first aid measures

Inhalation : Call a POISON CENTER or doctor if you feel unwell. Remove to fresh air

and keep at rest in a position comfortable for breathing.

Skin contact : Get medical advice. If skin irritation occurs : Immediately call a POISON

CENTER or doctor. Specific treatment (see on this label). Wash with plenty of soap and

water. Wash contaminated clothing before reuse.

Eye contact : Immediately call a POISON CENTER or doctor. Rinse cautiously with

water for several minutes. Remove contact lenses, if present and easy to do. Continue

rinsing.

Ingestion : Obtain emergency medical attention. Do NOT induce vomiting. Rinse mouth.

Call a POISON CENTER or doctor if you feel unwell.

4.2. Most important symptoms and effects, both acute and delayed

Symptoms relating to use : Repeated exposure to this material can result in absorption

through skin causing significant health hazard. Swallowing a small quantity of this

material will result in serious health hazard. Causes serious eye damage. Causes skin

irritation. May cause respiratory irritation.

4.3. Indication of any immediate medical attention and special treatment needed

General information : Never give anything by mouth to an unconscious person. If you

feel unwell, seek medical advice (show the label where possible).

5.1. Extinguishing media

Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.

Unsuitable extinguishing media : Do not use a heavy water stream.

Surrounding fires : Use water spray or fog for cooling exposed containers.

5.2. Special hazards arising from the substance or mixture

Hazardous combustion products : Under fire conditions, hazardous fumes will be

present

5.3. Advice for fire-fighters

Protection against fire : Do not enter fire area without proper protective equipment,

including respiratory protection.

Special procedures : Exercise caution when fighting any chemical fire. Avoid (reject)

fire-fighting water to enter environment

6.1. Personal precautions, protective equipment and emergency procedures

For emergency responders : Equip cleanup crew with proper protection.

Ventilate area.

For non-emergency personnel : Evacuate unnecessary personnel.

6.2. Environmental precautions

Environmental precautions : Prevent entry to sewers and public waters. Notify

authorities if product enters sewers or public waters. Avoid release to the environment.

6.3. Methods and material for containment and cleaning up

Clean up methods : Soak up spills with inert solids, such as clay or diatomaceous earth

as soon as possible. Store away from other materials. Collect spillage.

6.4. Reference to other sections

See section 8. Exposure controls/personal protection

9.1. Information on basic physical and chemical properties

Physical state at 20 °C : Solid.

Odour threshold : No data available.

pH value : No data available.

Melting point [°C] : 52°C

Decomposition point [°C] : N/A

Critical temperature [°C] : N/A

Auto-ignition temperature [°C] : N/A

Flammability (solid, gas) : N/A

Flash point [°C] : N/A

Boiling point [°C] : 253°C

Initial boiling point [°C] : N/A

Final boiling point [°C] : N/A

Evaporation rate : N/A

Vapour pressure [20°C] : N/A

Vapour pressure mm/Hg : N/A

Vapour density : N/A

Density [g/cm3] : 1,22

Relative density, gas (air=1) : N/A

Relative density, liquid (water=1) : N/A

Solubility in water [% weight] : Slightly soluble

Solubility in water : N/A

Log Pow octanol / water at 20°C : No data available.

Solubility : N/A

Viscosity at 40°C [mm2/s] : N/A

9.2. Other information

Explosive properties : N/A

Explosion limits - upper [%] : N/A

Explosion limits - lower [%] : N/A

Oxidising properties : No data available.

11.1. Information on toxicological effects

Acute toxicity

• Inhalation : Based on available data, the classification criteria are not met.

• Dermal : Harmful in contact with skin.

• Ingestion : Harmful if swallowed.

Corrosion : Causes serious eye damage.

Irritation : Causes skin irritation. May cause respiratory irritation.

Sensitization : Based on available data, the classification criteria are not met.

Mutagenicity : Based on available data, the classification criteria are not met.

Carcinogenicity : Based on available data, the classification criteria are not met.

Toxic for reproduction : Based on available data, the classification criteria are not met.

STOT-single exposure : Based on available data, the classification criteria are not met.

STOT-repeated exposure : Based on available data, the classification criteria are not

met.

Aspiration hazard : Based on available data, the classification criteria are not met.

12.1. Toxicity

Toxicity information : Very toxic to aquatic life with long lasting effects.

12.2. Persistence - degradability

Persistence - degradability : May cause long-term adverse effects in the environment.

12.3. Bioaccumulative potential

Bioaccumulative potential : Not established.

12.4. Mobility in soil

Mobility in soil : Not established.

12.5. Results of PBT and vPvB assessment

Results of PBT and vPvB assessment : The substance does not fulfil the criteria to be

identified as PBT substance or vPvB substance according to Annex XIII of Regulation

REACH.

12.6. Other adverse effects

Environmental precautions : Avoid release to the environment.

13.1. Waste treatment methods

General : Avoid release to the environment. Dispose in a safe manner in accordance with

local/national regulations. Dispose of this material and its container to hazardous or

special waste collection point, in accordance with local, regional, national and/or

international regulation.

15.1. Safety, health and environmental regulations/legislation specific for the

substance or mixture

Safety, health and environmental : Ensure all national/local regulations are observed.

regulations/legislation specific for the substance or mixture

REACH Restrictions - Annex XVII : The components of this product are not subject to

restrictions.

REACH Authorisation - Annex XIV : The components of this product are not subject

to authorization.

15.2. Chemical Safety Assessment

Chemical Safety Assessment : It has not been carried out.

Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.

vPvB: very persistent and very bioaccumulative

Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN

PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,

labelling and packaging of substances and mixtures, amending and repealing Directives

67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006

Further information : None.

In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation

(CE) Nº 1272/2008 

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.