HEPES BUFFER
- Part number
- RXSOL-60-6604-670
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
HEPES BUFFER A biological buffer (exist in a zwitterionic form ). It maintains physiological pH in cell culture when compared to bicarbonate buffers despite the changes in carbon dioxide concentration.HEPES is a zwitterionic organic chemical buffering agent; one of the twenty Good's buffers.
HEPES BUFFER A biological buffer (exist in a zwitterionic form ). It maintains physiological pH in cell culture when compared to bicarbonate buffers despite the changes in carbon dioxide concentration.HEPES is a zwitterionic organic chemical buffering agent; one of the twenty Good's buffers.
HEPES BUFFER A biological buffer (exist in a zwitterionic form ). It maintains physiological pH in cell culture when compared to bicarbonate buffers despite the changes in carbon dioxide concentration.HEPES is a zwitterionic organic chemical buffering agent; one of the twenty Good's buffers.
HEPES BUFFER A biological buffer (exist in a zwitterionic form ). It maintains physiological pH in cell culture when compared to bicarbonate buffers despite the changes in carbon dioxide concentration.HEPES is a zwitterionic organic chemical buffering agent; one of the twenty Good's buffers.
Applications
Dosage and directions
The recommended dosage is 70 mg/m2 irinotecan (4.3 mg/ml) resulting in an average male (1.9 m2) receiving a total amount of 133 mg of the drug and 126 mg of HEPES. This amount of administered HEPES is much higher than the recommended 200 μg per dose for gallium-68 based radiopharmaceuticals
Characteristics and notes
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name |
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| Product Type | HEPES (BUFFER) | |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance : Hepes (Buffer)
Substance.
Contains no other components or impurities which will influence the classification of the
product.
3.1 Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
3.2 Label elements
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
3.3 Other hazards – none
4.1 Description of first aid measures
•If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
•In case of skin contact
Wash off with soap and plenty of water.
•In case of eye contact
Flush eyes with water as a precaution.
•If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see
section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Sulphur oxides
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information
No data available
6.1 Personal precautions, protective equipment and emergency procedures
Avoid breathing vapours, mist or gas. For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Keep in suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Light sensitive. Storage class (TRGS 510): Non Combustible Liquids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
8.1 Control parameters
8.2 Exposure controls
• Appropriate engineering controls
General industrial hygiene practice.
• Personal protective equipment
• Eye/face protection
Use equipment for eye protection tested and approved under appropriate government
standards such as NIOSH (US) or EN 166(EU).
• Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal
technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good
laboratory practices. Wash and dry hands.
If used in solution, or mixed with other substances, and under conditions which differ
from EN 374, contact the supplier of the CE approved gloves. This recommendation is
advisory only and must be evaluated by an industria situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use
scenario.
• Body Protection
Impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
• Respiratory protection
Respiratory protection not required. For nuisance exposures use type OV/AG (US) or
type ABEK (EU EN 14387) respirator cartridges. Use respirators and components tested
and approved under appropriate government standards such as NIOSH (US) or CEN
(EU).
• Control of environmental exposure
Do not let product enter drains.
9.1 Information on basic physical and chemical properties
Odour Threshold : No data available
pH :5.0 - 6.0
Melting point/freezing point : No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas) :No data available
Upper/lower flammability or explosive limits : No data available
Vapour pressure : No data available
Vapour density : No data available
Relative density: 1.070 g/cm3
Water solubility No data available
Partition coefficient: noctanol/ water : No data available
Auto-ignition temperature: No data available
Decomposition temperature : No data available
Viscosity : No data available
Explosive properties: No data available
Oxidizing properties :No data available
9.2 Other safety information
No data available
10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides,
Nitrogen oxides (NOx), Sulphur oxides Other decomposition products - No data available
In the event of fire: see section 5
11.1 Information on toxicological effects
• Acute toxicity
No data available
• Skin corrosion/irritation
No data available
• Serious eye damage/eye irritation
No data available
• Respiratory or skin sensitisation
No data available
• Germ cell mutagenicity
No data available
• Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
• Reproductive toxicity
No data available
• Specific target organ toxicity - single exposure
No data available
• Specific target organ toxicity - repeated exposure
No data available
• Aspiration hazard
No data available
• Additional Information
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have
not been thoroughly investigated.
12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects No data available
13.1 Waste treatment methods
Product Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.
14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
[HEPES BUFFER] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
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