BENZAMIDE FOR SYNTHESIS
- Part number
- RXSOL-60-6604-037
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
ABSTRACT The benzamide chromophore is widely used as a Cottono- genic derivative of primary amines for stereochemical studies by circular dichroism. The assignments based on the exciton chirality method are reliable since the benzamide group has well-defined geometry and con- formation.
ABSTRACT The benzamide chromophore is widely used as a Cottono- genic derivative of primary amines for stereochemical studies by circular dichroism. The assignments based on the exciton chirality method are reliable since the benzamide group has well-defined geometry and con- formation.
ABSTRACT The benzamide chromophore is widely used as a Cottono- genic derivative of primary amines for stereochemical studies by circular dichroism. The assignments based on the exciton chirality method are reliable since the benzamide group has well-defined geometry and con- formation.
ABSTRACT The benzamide chromophore is widely used as a Cottono- genic derivative of primary amines for stereochemical studies by circular dichroism. The assignments based on the exciton chirality method are reliable since the benzamide group has well-defined geometry and con- formation.
ABSTRACT The benzamide chromophore is widely used as a Cottono- genic derivative of primary amines for stereochemical studies by circular dichroism. The assignments based on the exciton chirality method are reliable since the benzamide group has well-defined geometry and con- formation.
Technical specifications
Information on basic physical and chemical properties
| Odour threshold | No data available |
|---|---|
| pH | 9 |
| Relative evaporation rate (butylacetate=1) | No data available |
| Melting point | 125 - 128 °C |
| Freezing point | No data available |
| Boiling po int | 88 °C |
| Flash point | 180 °C |
| Auto-ignition temperature | No data available |
| Decomposition temperature | No data available |
| Flammability (solid, gas) | No data available |
| RelativeVapour pressure | No data available |
| vapour density at 20 °C | No data available |
| Relative density | No data available |
| Density | 1.341 g/cm³ |
| Solubility | Water: Moderate (1 - 10%) |
| Log Pow | 4 |
| Viscosity, kinematic | No data available |
| Viscosity, dynamic | No data available |
| Explosive properties | No data available |
| Oxidising properties | No data available |
| Explosive limits | No data available |
Applications
BENZOIC ACID amides. A selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia.
Dosage and directions
Benzamide synthesis by direct electrophilic aromatic substitution with cyanoguanidine.
Characteristics and notes
benzamides are used widely in the pharmaceutical, paper and plastic industries, and also as an intermediate product in the synthesis of therapeutic agents, the presented new synthetic methods for this type of compounds can be of considerable importance.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | RXSOL-60-6604-037 |
| Product Type | BENZAMIDE FOR SYNTHESIS |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
.3.1. Substances: BENZAMIDE FOR SYNTHESIS
CAS-No. : 55-21-0
Substance. Contains no other components or impurities which will influence the classification of the
product.
2.1. Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Acute toxicity (oral), H302
Category 4
Germ cell mutagenicity, H341
Category 2
Full text of hazard classes and H-statements : see section 16
Classification according to Directive 67/548/EEC [DSD] or 1999/45/EC [DPD]
Muta.Cat.3; R68
Xn; R22
Full text of R-phrases: see section 16
Adverse physicochemical, human health and environmental effects
No additional information available
2.2. Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP] Extra labelling to display
Extra classification(s) to display
Symbol(s) : Xn: Harmful
R Phrase(s) : R22 : Harmful if swallowed.
R68 : Possible risk of irreversible effects.
S Phrase(s) : S36/37 : Wear suitable protective clothing and gloves.
Hazard pictograms
Signal word : Warning
Hazard statements : H302 - Harmful if swallowed.
H341 - Suspected of causing genetic defects.
Precautionary statements : P281 - Use personal protective equipment as required.
2.3. Other hazards
No additional information available
4.1. Description of first aid measures
First-aid measures after inhalation : Remove person to fresh air and keep comfortable for breathing.
First-aid measures after skin contact : Gently wash with plenty of soap and water.
First-aid measures after eye contact : Remove contact lenses, if present and easy to do.
Continue rinsing. Rinse cautiously with water for several minutes.
First-aid measures after ingestion : Rinse mouth. Call a POISON CENTER/doctor if you feel unwell.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms/effects after ingestion : Harmful if swallowed.
4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.
5.1. Extinguishing media
Suitable extinguishing media : Carbon dioxide. Dry powder. Foam. Water spray.
Unsuitable extinguishing media : Do not use a heavy water stream.
5.2. Special hazards arising from the substance or mixture
No additional information available
5.3. Advice for firefighters
Protection during firefighting : Do not enter fire area without proper protective
equipment, including respiratory protection.
6.1. Personal precautions, protective equipment and emergency procedures
6.1.1. For non-emergency personnel
Emergency procedures : Evacuate unnecessary personnel.
6.1.2. For emergency responders
Protective equipment : Equip cleanup crew with proper protection.
6.2. Environmental precautions
Avoid release to the environment.
6.3. Methods and material for containment and cleaning up
Methods for cleaning up : Soak up spills with inert solids, such as clay or diatomaceous
earth as soon as possible. On land, sweep or shovel into suitable containers.
6.4. Reference to other sections
No additional information available
7.1. Precautions for safe handling
Precautions for safe handling : Avoid contact with skin and eyes. Do not breathe vapours.
Avoid dust formation.
Hygiene measures : Do not eat, drink or smoke when using this product. Wash hands and
other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
7.2. Conditions for safe storage, including any incompatibilities
Storage conditions : Store in a well-ventilated place. Keep container tightly closed.
7.3. Specific end use(s)
No additional information available
8.1. Control parameters
No additional information available
8.2. Exposure controls
Hand protection : Protective gloves
Eye protection : Chemical goggles or safety glasses
Skin and body protection : Wear suitable protective clothing
Respiratory protection : Where exposure through inhalation
may occur from use, respiratory protection equipment is recommended
9.1. Information on basic physical and chemical properties
Odour threshold : No data available
pH : 6.9
Relative evaporation rate (butylacetate=1) : No data available
Melting point : 125 - 128 °C
Freezing point : No data available
Boiling point : 288 °C
Flash point : 180 °C
Auto-ignition temperature : No data available
Decomposition temperature : No data available
Flammability (solid, gas) : No data available
Vapour pressure : No data available Relative
vapour density at 20 °C : No data available
Relative density : No data available
Density : 1.341 g/cm³
Solubility : Water: Moderate (1 - 10%)
Log Pow : 0.64
Viscosity, kinematic : No data available
Viscosity, dynamic : No data available
Explosive properties : No data available
Oxidising properties : No data available
Explosive limits : No data available
9.2. Other information
No additional information available
10.1. Reactivity
No additional information available
10.2. Chemical stability
Stable under normal conditions.
10.3. Possibility of hazardous reactions
No additional information available
10.4. Conditions to avoid
Direct sunlight. Air contact. Moisture.
10.5. Incompatible materials
No additional information available
10.6. Hazardous decomposition products
No additional information available
11.1. Information on toxicological effects
Acute toxicity : Oral: Harmful if swallowed.
Skin corrosion/irritation : Not classified
pH: 6.9
Serious eye damage/irritation : Not classified
pH: 6.9
Respiratory or skin sensitisation : Not classified
Germ cell mutagenicity : Suspected of causing genetic defects.
Carcinogenicity : Not classified
Reproductive toxicity : Not classified
STOT-single exposure : Not classified
STOT-repeated exposure : Not classified
Aspiration hazard : Not classified
Potential adverse human health effects
and symptoms : Harmful if swallowed.
12.1. Toxicity
No additional information available
12.2. Persistence and degradability
No additional information available
12.3. Bioaccumulative potential
Log Pow 0.64
12.4. Mobility in soil
No additional information available
12.5. Results of PBT and vPvB assessment
No additional information available
12.6. Other adverse effects
No additional information available
13.1. Waste treatment methods
Product/Packaging disposal
Recommendations : Dispose of contents/container to hazardous or special waste
collection point, in accordance with local, regional, national and/or international regulation.
In accordance with ADR / RID / IMDG / IATA / ADN
14.1. UN number
UN-No. (ADR) : Not applicable
UN-No. (IMDG) : Not applicable
UN-No. (IATA) : Not applicable
UN-No. (ADN) : Not applicable
UN-No. (RID) : Not applicable
14.2. UN proper shipping name
Proper Shipping Name (ADR) : Not applicable
Proper Shipping Name (IMDG) : Not applicable
Proper Shipping Name (IATA) : Not applicable
Proper Shipping Name (ADN) : Not applicable
Proper Shipping Name (RID) : Not applicable
14.3. Transport hazard class(es)
ADR : Transport hazard class(es) (ADR) : Not applicable
IMDG : Transport hazard class(es) (IMDG) : Not applicable
IATA : Transport hazard class(es) (IATA) : Not applicable
ADN : Transport hazard class(es) (ADN) : Not applicable
RID : Transport hazard class(es) (RID) : Not applicable
14.4. Packing group
Packing group (ADR) : Not applicable
Packing group (IMDG) : Not applicable
Packing group (IATA) : Not applicable
Packing group (ADN) : Not applicable
Packing group (RID) : Not applicable
14.5. Environmental hazards
Dangerous for the environment : No
Marine pollutant : No
Other information : No supplementary information available
14.6. Special precautions for user
- Overland transport
No data available
- Transport by sea
No data available
- Air transport
No data available
- Inland waterway transport
No data available
- Rail transport No data available
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable
ADR - Packing instructions : P001
ADR - Limited Quantity : 1 L
ADR - Tunnel code : D/E : Bulk or tank carriage: Passage forbidden through tunnels of
category D and
E. Other carriage: Passage forbidden through tunnels of category E.
14.2. Sea transport (IMDG) [English only]
Proper shipping name : ACETIC ACID,
UN N° : 2789
IMO-IMDG - Class or division : 8 : Corrosive substance. ( 3 : Flammable liquid. )
IMO-IMDG - Packing group : II
IMO- IMDG - Packing instructions : P001
IMO-IMDG - Limited quantities : 1 L
IMO-IMDG - Marine pollution : No
EMS-Nr : F-E S-C
14.3. Air transport (ICAO-IATA) [English only]
Proper shipping name : ACETIC ACID
UN N° : 2789
IATA - Class or division : 8 : Corrosive substance. ( 3 : Flammable liquid. )
IATA - Packing group : II
IATA - Passenger and Cargo Aircraft : ALLOWED
- Passenger and Cargo - Packing : 851
instruction
- Passenger and Cargo - Maximum : 1 L
Quantity/Packing
IATA - Cargo only : ALLOWED
- Cargo only - Packing instruction : 855
- Cargo only - Maximum Quantity/ : 30 L
Packing
IATA - Limited Quantites : 0.5 L
ERG-Nr : 8F
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
15.1.1. EU-Regulations
No REACH Annex XVII restrictions BENZAMIDE FOR SYNTHESIS is not on the REACH Candidate List
BENZAMIDE FOR SYNTHESIS is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
12th Ordinance Implementing the Federal
Immission Control Act - 12.BImSchV : Is not subject of the 12. BlmSchV (Hazardous Incident Ordinance)
Netherlands
SZW-lijst van kankerverwekkende stoffen : The substance is not listed
SZW-lijst van mutagene stoffen : The substance is not listed
NIET-limitatieve lijst van voor de voortplanting giftige stoffen – Borstvoeding : The substance is not listed
NIET-limitatieve lijst van voor de voortplanting giftige stoffen – Vruchtbaarheid : The substance is not listed
NIET-limitatieve lijst van voor de voortplanting giftige stoffen – Ontwikkeling : The substance is not listed
Denmark
Recommendations Danish Regulation : Young people below the age of 18 years are not allowed to use the product
Pregnant/breastfeeding women working with the product must not be in direct contact with the product
The requirements from the Danish Working Environment Authorities regarding work with carcinogens
must be followed during use and disposal
15.2. Chemical safety assessment
No additional information available
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
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