COLCHICINE
- Part number
- RXSOL-60-6604-350
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Colchicine is a medicine for treating inflammation and pain.
It can be used to: treat flare-ups (attacks) of gout.
prevent increased flare-ups of gout when you first start on a medicine like allopurinol – taken to manage your condition long term.
Applications
Colchicine is widely used in plant breeding by inducing polyploidy in plant cells to produce new or improved varieties, strains and cultivars. When used to induce polyploidy in plants, colchicine cream is usually applied to a growth point of the plant, such as an apical tip, shoot, or sucker.
Dosage and directions
the recommended dosage of colchicine capsules is 0.6 mg once or twice daily. The maximum dose is 1.2 mg per day.
Characteristics and notes
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name |
|
|
| Product Type | COLOCHICINE | |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
2.1. Substances: COLCHICINE
CAS-No. : 64-86-8
Substance.
Contains no other components or impurities which will influence the classification of the
product.
3.1. Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Acute toxicity (oral), H300
Category 1
Acute toxicity (inhal.), H330
Category 1
Serious eye damage/eye irritation, H318
Category 1
Germ cell mutagenicity, H340
Category 1B
Classification according to Directive 67/548/EEC [DSD] or 1999/45/EC [DPD]
Adverse physicochemical, human health and environmental effects
No additional information available
3.2. Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP] Extra labelling to
displayExtra classification(s) to display
Symbol(s) : T : Very toxic
R Phrase(s) : R26/28 : Very toxic by Inhalation and if swallowed.
S Phrase(s) : S1 : Keep locked up.
S3: Keep in a cool place.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the
label where possible).
Hazard pictograms :
Signal word : Danger
Hazard statements : H300+H330 - Fatal if swallowed or if inhaled
H318 - Causes serious eye damage.
H340 - May cause genetic defects.
Precautionary statements : P201 - Obtain special instructions before use.
P260 - Do not breathe vapours, spray, dust, fume, gas.
P264 - Wash hands, forearms and face thoroughly after handling.
P280 - Wear protective gloves, protective clothing, eye protection, face protection.
P284 - Wear respiratory protection.
P301+P310 - IF SWALLOWED: Immediately call a doctor.
3.3. Other hazards
No additional information available
4.1. Description of first aid measures
First-aid measures after inhalation : Assure fresh air breathing. Allow the victim to rest.
First-aid measures after skin contact : Wash with plenty of water/…. Remove affected
clothing and wash all exposed skin area with mild soap and water, followed by warm
water rinse. Get immediate medical advice/attention.
First-aid measures after eye contact : Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing. Get medical
advice/attention.
First-aid measures after ingestion : Rinse mouth. Immediately call a POISON
CENTER/doctor.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms/effects : May cause genetic defects.
Symptoms/effects after eye contact : Causes serious eye damage.
Symptoms/effects after ingestion : Fatal if swallowed.
4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically.
5.1. Extinguishing media
Suitable extinguishing media : dry chemical powder, alcohol-resistant foam, carbon
dioxide (CO2).
Unsuitable extinguishing media : Do not use a heavy water stream.
5.2. Special hazards arising from the substance or mixture
No additional information available
5.3. Advice for firefighters
Protection during firefighting : Do not enter fire area without proper protective
equipment, including respiratory protection.
6.1. Personal precautions, protective equipment and emergency procedures
6.1.1. For non-emergency personnel
Emergency procedures : Evacuate unnecessary personnel.
6.1.2. For emergency responders
Protective equipment : Use personal protective equipment as required.
Emergency procedures : Ventilate area.
6.2. Environmental precautions Avoid release to the environment.
6.3. Methods and material for containment and cleaning up
Methods for cleaning up : Soak up spills with inert solids, such as clay or diatomaceous
earth as soon as possible. On land, sweep or shovel into suitable containers.
6.4. Reference to other sections
No additional information available
7.1. Precautions for safe handling
Precautions for safe handling : Obtain special instructions before use. Do not breathe
vapours. Avoid contact with skin and eyes.
Hygiene measures : Do not eat, drink or smoke when using this product. Wash hands and
other exposed areas with mild soap and water before eating, drinking or smoking and
when leaving work.
7.2. Conditions for safe storage, including any incompatibilities
Storage conditions : Store in a well-ventilated place. Keep container tightly closed.
7.3. Specific end use(s)
No additional information available
8.1. Control parameters
No additional information available
8.2. Exposure controls
Hand protection : Protective gloves
Eye protection : Chemical goggles or safety glasses
Skin and body protection : Wear suitable protective clothing
Respiratory protection : [In case of inadequate ventilation] wear respiratory protection.
9.1. Information on basic physical and chemical properties
Odour threshold : No data available
pH : 6
Relative evaporation rate (butylacetate=1) : No data available
Melting point : 150 - 160 °C
Freezing point : No data available
Boiling point : No data available
Flash point : No data available
Auto-ignition temperature : No data available
Decomposition temperature : No data available
Flammability (solid, gas) : No data available
Vapour pressure : No data available
Relative vapour density at 20 °C : No data available
Relative density : No data available
Solubility : Water: Soluble Log Pow : No data available
Viscosity, kinematic : No data available
Viscosity, dynamic : No data available
Explosive properties : No data available
Oxidising properties : No data available
Explosive limits : No data available
9.2. Other information
No additional information available
10.1. Reactivity
No additional information available
10.2. Chemical stability
Stable under normal conditions.
10.3. Possibility of hazardous reactions
No additional information available
10.4. Conditions to avoid
Air contact. Direct sunlight.
10.5. Incompatible materials
No additional information available
10.6. Hazardous decomposition products
No additional information available
11.1. Information on toxicological effects
Acute toxicity : Oral: Fatal if swallowed.
Inhalation: Fatal if inhaled.
Skin corrosion/irritation : Not classified
pH: 6
Serious eye damage/irritation : Causes serious eye damage.
pH: 6
Respiratory or skin sensitisation : Not classified
Germ cell mutagenicity : May cause genetic defects.
Carcinogenicity : Not classified
Reproductive toxicity : Not classified
STOT-single exposure : Not classified
STOT-repeated exposure : Not classified
Aspiration hazard : Not classified
Potential adverse human health effects and symptoms : Fatal if swallowed.
12.1. Toxicity
No additional information available
12.2. Persistence and degradability
No additional information available
12.3. Bioaccumulative potential
No additional information available
12.4. Mobility in soil
No additional information available
12.5. Results of PBT and vPvB assessment
No additional information available
12.6. Other adverse effects
No additional information available
13.1. Waste treatment methods
Product/Packaging disposal Recommendations : Dispose of contents/container to hazardous or special waste
collection point, in accordance with local, regional, national and/or international
regulation.
Ecology - waste materials : Hazardous waste due to toxicity.
In accordance with ADR / RID / IMDG / IATA / ADN
14.1. UN number
UN-No. (ADR) : 1544
UN-No. (IMDG) : 1544
UN-No. (IATA) : 1544
UN-No. (ADN) : 1544
UN-No. (RID) : 1544
14.2. UN proper shipping name
Proper Shipping Name (ADR) : ALKALOIDS, SOLID, N.O.S.
Proper Shipping Name (IMDG) : ALKALOIDS, SOLID, N.O.S.
Proper Shipping Name (IATA) : Alkaloid salts, solid, n.o.s.
Proper Shipping Name (ADN) : ALKALOIDS, SOLID, N.O.S.
Proper Shipping Name (RID) : ALKALOIDS, SOLID, N.O.S.
Transport document description (ADR) : UN 1544 ALKALOIDS, SOLID,N.O.S., 6.1, I,
(C/E)
Transport document description (IMDG) : UN 1544 ALKALOIDS, SOLID, N.O.S., 6.1, I
Transport document description (IATA) : UN 1544 Alkaloid salts, solid, n.o.s., 6.1, I
Transport document description (ADN) : UN 1544 ALKALOIDS, SOLID, N.O.S., 6.1, I
Transport document description (RID) : UN 1544 ALKALOIDS, SOLID, N.O.S., 6.1, I
14.3. Transport hazard class(es)
ADR- Transport hazard class(es) (ADR) : 6.1
Danger labels (ADR) : 6.1
IMDG- Transport hazard class(es) (IMDG) : 6.1
Danger labels (IMDG) : 6.1
IATA- Transport hazard class(es) (IATA) : 6.1
Hazard labels (IATA) : 6.1
ADN- Transport hazard class(es) (ADN) : 6.1
Danger labels (ADN) : 6.1
RID- Transport hazard class(es) (RID) : 6.1
Danger labels (RID) : 6.1
14.4. Packing group
Packing group (ADR) : I
Packing group (IMDG) : I
Packing group (IATA) : I
Packing group (ADN) : I
Packing group (RID) : I
14.5. Environmental hazards
Dangerous for the environment : No
Marine pollutant : No
Other information : No supplementary information available
14.6. Special precautions for user
Overland transport- Classification code (ADR) : T2
Special provisions (ADR) : 43, 274
Limited quantities (ADR) : 0
Excepted quantities (ADR) : E5
Packing instructions (ADR) : P002, IBC07
Mixed packing provisions (ADR) : MP18
Portable tank and bulk container instructions (ADR) : T6
Portable tank and bulk container special provisions (ADR) : TP33
Tank code (ADR) : S10AH Tank special provisions (ADR) : TU15, TE19
Vehicle for tank carriage : AT Transport category (ADR) : 1
Special provisions for carriage – Packages (ADR) : V10
Special provisions for carriage - Loading, unloading and handling (ADR) : CV1, CV13,
CV28
Special provisions for carriage – Operation (ADR) : S9, S14
Hazard identification number (Kemler No.) : 66
Orange plates :
Tunnel restriction code (ADR) : C/E
EAC code : 2X
Transport by sea- Special provisions (IMDG) : 43, 274
Packing instructions (IMDG) : P002
IBC packing instructions (IMDG) : IBC07
IBC special provisions (IMDG) : B1
Tank instructions (IMDG) : T6
Tank special provisions (IMDG) : TP33
EmS-No. (Fire) : F-A
EmS-No. (Spillage) : S-A
Stowage category (IMDG) : A
Properties and observations (IMDG) : A wide range of toxic solids, generally of
vegetable origin. Toxic if swallowed, by skin contact or by inhalation.
MFAG-No : 151
Air transport- PCA Excepted quantities (IATA) : E5
PCA Limited quantities (IATA) : Forbidden
PCA limited quantity max net quantity (IATA) : Forbidden
PCA packing instructions (IATA) : 666
PCA max net quantity (IATA) : 5kg
CAO packing instructions (IATA) : 673
CAO max net quantity (IATA) : 50kg
Special provisions (IATA) : A3, A4, A6, A801
ERG code (IATA) : 6L
Inland waterway transport- Classification code (ADN) : T2
Special provisions (ADN) : 43, 274, 802
Limited quantities (ADN) : 0
Excepted quantities (ADN) : E5
Equipment required (ADN) : PP, EP
Number of blue cones/lights (ADN) : 2
Rail transport- Classification code (RID) : T2
Special provisions (RID) : 43, 274
Limited quantities (RID) : 0
Excepted quantities (RID) : E5
Packing instructions (RID) : P002, IBC07
Mixed packing provisions (RID) : MP18
Portable tank and bulk container instructions (RID) : T6
Portable tank and bulk container special provisions (RID) : TP33
Tank codes for RID tanks (RID) : S10AH
Special provisions for RID tanks (RID) : TU15
Transport category (RID) : 1
Special provisions for carriage – Packages (RID) : W10
Special provisions for carriage - Loading, unloading and handling (RID) : CW13, CW28,
CW31
Hazard identification number (RID) : 66
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable
15.1. Safety, health and environmental regulations/legislation specific for the
substance or mixture
15.1.1. EU-Regulations
No REACH Annex XVII restrictions
COLCHICINE is not on the REACH Candidate List
COLCHICINE is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
Reference to AwSV : Water hazard class (WGK) 3, severe hazard to water (Classification
according to AwSV; ID No. 888)
12th Ordinance Implementing the Federal
Immission Control Act - 12.BImSchV : Is not subject of the 12. BlmSchV (Hazardous
Incident Ordinance)
Netherlands
SZW-lijst van kankerverwekkende stoffen : The substance is not listed
SZW-lijst van mutagene stoffen : COLCHICINE Extra Pure is listed
NIET-limitatieve lijst van voor de
voortplanting giftige stoffen – Borstvoeding : The substance is not listed
NIET-limitatieve lijst van voor de
voortplanting giftige stoffen –
Vruchtbaarheid : The substance is not listed
NIET-limitatieve lijst van voor de
voortplanting giftige stoffen – Ontwikkeling : The substance is not listed
Denmark
Recommendations Danish Regulation : Young people below the age of 18 years are not
allowed to use the product
Pregnant/breastfeeding women working with the product must not be in direct
contact with the product
The requirements from the Danish Working Environment Authorities regarding work
with carcinogens must be followed during use and disposal
15.2. Chemical safety assessment
No additional information available
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
COLCHICINE manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
COLCHICINE is available in small packing as well as in bulk. Buy premium quality COLCHICINE and other lab chemicals from one of the most trusted brands.
