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Chloral Hydrate

Chloral Hydrate, a sedative, is used in the short-term treatment of insomnia (to help you fall asleep and stay asleep for a proper rest) and to relieve anxiety and induce sleep before surgery
Part number
RXSOL-19-1540-252
Category
Medicine
Brand
RXSOL
RXSOL

Overview

Chloral Hydrate, a sedative, is used in the short-term treatment of insomnia (to help you fall asleep and stay asleep for a proper rest) and to relieve anxiety and induce sleep before surgery. It is also used after surgery for pain and to treat alcohol withdrawal.

Applications

Chloral Hydrate CAS No. 302-17-0
For electroplating industry, chloral hydrate can used to adjust the electronic potential difference in semi-bright nickel electroplating; it can effectively remove the active sulfur in the bath and improve the electronic potential difference.

Characteristics and notes

For agriculture, it can be used as intermediate of herbicides and other types of pesticides.

Safety and SDS

Read the safety data sheet before handling. Wear suitable gloves and eye protection.

View safety data sheet
Porduct Name               Chloral Hydrate
Part Number   RXSOL-19-1540-252

Company Details:....

RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA

Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA  

Phone +91 22 20871200 - 1400
Fax +91 22 27612100 :::AOH :0091 9821214367
Email rxsolchemicals@gmail.com
Website www.rxmraine.com
Chemical Name                 Cas No                        EC No              Whight                          Formula                   
Chloral Hydrate 302-17-0 206-117-5 165,40 g/mol C2H3Cl3O2
Component                   Classification                            Concentration                           
Chloral monohydrate                                                                                                                - -
CAS-No. - 302-17-0 Acute Tox. 3; Skin Irrit. 2; <= 100 %
EC-No. - 206-117-5 Eye Irrit. 2; H301, H315,  
Index-No. - 605-014-00-6 H319  
Reduced Labeling (<= 125 ml)
Pictogram
Signal Word  Danger
Hazard Statements H301 Toxic if swallowed.

Precautionary statements  

P264

P301 + P310

Wash skin thoroughly after handling.

IF SWALLOWED: Immediately call a POISON CENTER/

Supplemental Hazard      Statements None
Other hazards 

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Ecological information:

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Toxicological information: The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

Description of first-aid measures

General advice Show this material safety data sheet to the doctor in attendance.
If inhaled After inhalation: fresh air.
Eye Contact  After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
Swallowed If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.
Skin Contact   In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
Most important symptoms and effects, both acute and delaye The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed  No data available

Extinguishing media

Unsuitable extinguishing media For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture 

Carbon oxides

Hydrogen chloride gas

Not combustible.

Ambient fire may liberate hazardous vapours.                                                                                        

Advice for firefighters Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Further information Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Enviromental Precaution Do not let product enter drains.
Methods and materials for
containment and cleaning
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Reference to other sections    For disposal see section 13. 
Precautions for safe handling For precautions see section 2.2.
Storage conditions Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.                                                                                                                                                Air and light sensitive.
Storage class Storage class (TRGS 510): 6.1B: Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
Specific end     use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

Control parameters

Ingredients with workplace control parameters

Exposure controls

Personal protective equipment

Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L
Body Protection protective clothing
Respiratory protection
required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Control of    environmental exposure Do not let product enter drains.
Physical state Crystalline
Colour White
Odour No data available
Odor Threshold Not Applicable
pH 3,5 - 4,4 at 100 g/l
Melting point/freezing point Melting point/range: 57 °C - lit.
Initial boiling point and boiling range 100,66 °C at 973,8 hPa - OECD Test Guideline 103
Flash Point Not applicable
Evaporation Rate Not Applicable
Flammability (solid, gas) The product is not flammable.
Explosive limits No Data Available
Upper/lower flammability or explosive limits No data available
Autoignition temperature No data available
Decomposition temperature  No data available
Vapour pressure 20 hPa at 25 °C                                                
Viscosity Viscosity, kinematic: No data available Viscosity, dynamic: No data available  
Density 0,947 g/cm3 at 28,9 °C - OECD Test Guideline 109
Relative Density No data available
Relative vapor density No data available
Particle characteristics Particle Size Distribution  D50 = 150 µm Type of distribution: mass distribution
Specific Gravity No data available 
Explosive properties No data available 
Water Solubility 443,69 g/l at 25 °C - completely soluble
Partition coefficient: n-octanol/water log Pow: 1,092 at 25 °C - Bioaccumulation is not expected.
Oxidizing properties None
Other safety information       No data available                           
Reactivity                        No data available
Chemical stability The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions Violent reactions possible with: Strong oxidizing agents permanganates Alcohols Bases Alkali metals Alkaline earth metals tannin
Conditions to avoid Air Light. no information available                                                                                    
Incompatible materials
iron/iron-containing compounds, various plasticsStrong oxidizing agents
Hazardous decomposition products In the event of fire: see section 5

Information on toxicological effects

Acute toxicity  Acute toxicity estimate Oral - 100,1 mg/kg (Expert judgment) Inhalation: No data available LD50 Dermal - Rat - 3.030 mg/kg Remarks: (ECHA)                     
Skin corrosion/irritation Skin - Guinea pig Result: Skin irritation Remarks: (ECHA)
Serious eye      damage/irritation Remarks: No data available
Respiratory or skin    sensitization  Maximization Test - Guinea pig Result: negative Remarks: (ECHA)
Carcinogenicity No data available
Germ cell        mutagenicity 

Test Type: Ames test Test system: S. typhimurium Metabolic activation: with and without metabolic activation Result: negative Remarks: (ECHA)

Test Type: in vivo assay Species: Mouse Application Route: Intraperitoneal

Method: OECD Test Guideline 474 Result: negative 

Reproductive toxicity  No data available
Specific target organ toxicity - single      exposure No data available
Specific target organ toxicity - repeated exposure No data available
Aspiration hazard No data available
Additional Information Product: Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: FM8750000 Cough, Shortness of breath, Headache, Nausea, Vomiting, Drowsiness, Confusion., Amnesia. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Toxicity

Toxicity to fish  static test LC50 - Danio rerio (zebra fish) - > 100 mg/l - 96 h (OECD Test Guideline 203) 
Toxicity to daphnia and other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 500 mg/l - 48 h
Toxicity to bacteria  - Bacteria - 1,6 mg/l - 16 h - Protozoa - 79 mg/l - 72 h
Toxicity to algae IC50 - Scenedesmus quadricauda (Green algae) - 2,8 mg/l - 168 h
Toxicity to daphnia and other aquatic invertebrates(Chronic toxicity) semi-static test LC50 - Daphnia magna (Water flea) - > 96,2 mg/l - 21 d (OECD Test Guideline 211)
Persistence and degradability Biodegradability aerobic - Exposure time 28 d Result: 44,04 % - Not inherently biodegradable. (OECD Test Guideline 301F)
Bioaccumulative potential No data available
Mobility in soil No data available
Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. 
Endocrine disrupting properties Product: Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Other adverse effects No data available
Waste treatment      Method No data available
UN number ADR/RID : 2811         IMDG : 2811                    IATA : 2811
UN proper shipping name  ADR/RID :  TOXIC SOLID, ORGANIC, N.O.S. (chloral, monohydrate)   IMDG : TOXIC SOLID, ORGANIC, N.O.S. (chloral, monohydrate)   IATA : Toxic solid, organic, n.o.s. (chloral, monohydrate) Passenger Aircraft: Not permitted for transport
Transport hazard class(es)      ADR/RID : 6.1            IMDG : 6.1                      IATA : 6.1
Packaging group ADR/RID : I                IMDG :   I                        IATA : I
Environmental hazards ADR/RID: No                     IMDG: No                IATA: No
Special precautions for user Tunnel restriction code : (C/E)         Further information : No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
Authorisations and/or restrictions on use  National legislation : Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. H2 ACUTE TOXIC
Other regulations Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work.
Chemical Safety Assessment For this product a chemical safety assessment was not carried out
Other Information

The information above is believed to be accurate and represents the  best information   currently    available  to us.  However,   we   make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and  weassume  no liability resulting from its use. Users should make  their  own  investigations  to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International  has been advised of the possibility of such damages.

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.

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