DRABKIN S SOLUTION DILUENT
- Part number
- RXSOL-60-6604-517
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Drabkin's Reagent is used for the quantitative, colorimetric determination of hemoglobin concentration in whole blood at 540 nm. Drabkin's Solution reacts with all forms of hemoglobin except sulfhemoglobin, a pigment that normally occurs in only minute concentrations in blood.
Applications
Drabkin′s reagent is used in measuring haemoglobin from blood samples. It comprises potassium ferricyanide, potassium cyanide and potassium dihydrogen phosphate as components. Potassium ferricyanide oxidizes haemoglobin to methemoglobin and then to cyanmethemoglobin.
Dosage and directions
To all tubes, add 5.0 ml of the Drabkin's Solution. 4. To each tube labeled Test, add 20 µl of the whole blood sample, rinsing the pipette 3-4 times with reagent. Mix well and allow to stand for at least 15 minutes at room temperature
Characteristics and notes
The principle of this method lies in conversion of hemoglobin to cyanmethemoglobin by the addition of Potassium cyanide and ferricyanide whose absorbance is measured at 540 nm in a photoelectric calorimeter against a standard solution.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name |
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| Product Type |
DRABKIN’S SOLUTION (DILUENT) When it becomes trubid it should be discarded. Hametology reagent. |
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| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation : Preparation.
Hazardous component(s) : This product is not hazardous but contains hazardous
components.
Substance name Contents CAS No
Sodium bicarbonate : > 0.1 < 1 % 144-55-8
POTASSIUM FERRICYANIDE 98% : < 0.1 % 13746-66-2
Water : > 99 % 7732-18-5
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Not classified.
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not classified.
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Not classified.
Symbol(s) : None.
R Phrase(s) : None.
S Phrase(s) : None.
Labelling Regulation EC 1272/2008 (CLP)
Not classified.
3.3. Other hazards
Other hazards : The substance does not fulfil the criteria to be identified as PBT
substance or vPvB substance according to Annex XIII of Regulation REACH.
.
4.1. Description of first aid measures
Inhalation : Assure fresh air breathing. Allow the victim to rest. Immediately call a
POISON CENTER or doctor. Specific treatment (see on this label). Remove to fresh air
and keep at rest in a position comfortable for breathing.
Skin contact : Remove affected clothing and wash all exposed skin area with mild soap
and water, followed by warm water rinse. Specific treatment (see on this label).
Immediately call a POISON CENTER or doctor. Wash with plenty of soap and
water. Wash contaminated clothing before reuse. Remove/Take off immediately all
contaminated clothing.
Eye contact : Rinse immediately with plenty of water. Obtain medical attention if pain,
blinking or redness persist.
Ingestion : Obtain emergency medical attention. Rinse mouth. Specific treatment (see on
this label). Immediately call a POISON CENTER or doctor. Do NOT induce vomiting.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use : Repeated exposure to this material can result in absorption
through skin causing significant health hazard. Danger of serious damage to health by
prolonged exposure through inhalation. Swallowing a small quantity of this material will
result in serious health hazard.
4.3. Indication of any immediate medical attention and special treatment needed
General information : Never give anything by mouth to an unconscious person. If you
feel unwell, seek medical advice (show the label where possible).
5.1. Extinguishing media
Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media : Do not use a heavy water stream.
Surrounding fires : Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products : Under fire conditions, hazardous fumes will be
present.
5.3. Advice for fire-fighters
Protection against fire : Do not enter fire area without proper protective equipment,
including respiratory protection.
Special procedures : Exercise caution when fighting any chemical fire. Avoid (reject)
fire-fighting water to enter environment.
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders : Equip cleanup crew with proper protection.
Ventilate area.
For non-emergency personnel : Evacuate unnecessary personnel.
6.2. Environmental precautions
Environmental precautions : Prevent entry to sewers and public waters. Notify
authorities if product enters sewers or public waters. Avoid release to the environment.
6.3. Methods and material for containment and cleaning up
Clean up methods : Soak up spills with inert solids, such as clay or diatomaceous earth
as soon as possible. Collect spillage. Store away from other materials.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling : Avoid breathing dust, fume, gas, mist, vapours, spray. Do not eat, drink or
smoke when using this product. Wash thoroughly after handling. Use only outdoors or in
a well-ventilated area.
Technical protective measures : Provide good ventilation in process area to prevent
formation of vapour.
7.2. Conditions for safe storage, including any incompatibilities
Storage : Keep only in the original container in a cool, well ventilated place. Keep
container tightly closed.
Storage - away from : Strong bases. Strong acids. Sources of ignition. Direct sunlight.
7.3. Specific end use(s)
Specific end use(s) : None
8.1. Exposure controls
Personal protection : Avoid all unnecessary exposure.
• Respiratory protection : In case of insufficient ventilation, wear suitable respiratory
equipment.
• Hand protection : Wear protective gloves.
• Eye protection : Chemical goggles or safety glasses.
• Others : When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits : No data available.
9.1. Information on basic physical and chemical properties
Odour threshold : No data available.
Melting point [°C] : No data available.
Decomposition point [°C] : N/A
Flammability (solid, gas) : N/A
Boiling point [°C] : N/A
Evaporation rate : N/A
Vapour pressure mm/Hg : N/A
Vapour density : N/A
Density [g/cm3] : N/A
Relative density, gas (air=1) : N/A
Relative density, liquid (water=1) : N/A
Solubility in water [% weight] : N/A
Log Pow octanol / water at 20°C : No data available.
Solubility : N/A
9.2. Other information
Explosive properties : N/A Oxidising properties : No data available.
10.1. Reactivity
Reactivity : Highly reactive material.
10.2. Chemical stability
Chemical stability : Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions : Contact with acids liberates very toxic gas.
10.4. Conditions to avoid
Conditions to avoid : Direct sunlight. Extremely high or low temperatures.
10.5. Incompatible materials
Materials to avoid : Strong acids. Strong bases.
10.6. Hazardous decomposition products
Hazardous decomposition products : Fumes. Carbon monoxide. Carbon dioxide.
11.1. Information on toxicological effects
Toxicity information : The product has been not fully tested. The calculated risk has
been done under the requirements of the EU regulations.
Acute toxicity
• Inhalation : Toxic if inhaled.
• Dermal : Toxic in contact with skin.
• Ingestion : Toxic if swallowed.
Corrosion : Based on available data, the classification criteria are not met.
Irritation : Based on available data, the classification criteria are not met.
Sensitization : Based on available data, the classification criteria are not met.
Carcinogenicity : Based on available data, the classification criteria are not met.
Toxic for reproduction : Based on available data, the classification criteria are not met
. STOT-single exposure : Based on available data, the classification criteria are not met.
STOT-repeated exposure : Based on available data, the classification criteria are not
met.
Aspiration hazard : Based on available data, the classification criteria are not met.
12.1. Toxicity
Toxicity information : The product has been not fully tested. The calculated risk has
been done under the requirements of the EU regulations. Very toxic to aquatic life with
long lasting effects.
12.2. Persistence - degradability
Persistence - degradability : May cause long-term adverse effects in the environment.
12.3. Bioaccumulative potential
Bioaccumulative potential : Not established.
12.4. Mobility in soil
Mobility in soil : Not established.
12.5. Results of PBT and vPvB assessment
Results of PBT and vPvB assessment : The substance does not fulfil the criteria to be
identified as PBT substance or vPvB substance according to Annex XIII of Regulation
REACH.
12.6. Other adverse effects
Environmental precautions : Avoid release to the environment.
13.1. Waste treatment methods General : Avoid release to the environment. Dispose in a safe manner in accordance with
local/national regulations.
Dispose of this material and its container to hazardous or special waste collection
point, in accordance with local, regional, national and/or international regulation.
Special precautions : Hazardous waste due to toxicity.
14.1. Land transport (ADR-RID)
Proper shipping name : CYANIDES, INORGANIC, SOLID, N.O.S.
UN N° : 1588
H.I. nr : 60
ADR - Class : 6.1
Labelling - Transport : 6.1 : Toxic substances.
ADR - Classification code : T5
ADR - Group : III
ADR - Packing instructions : P002 R001 LP002
ADR - Limited Quantity : 5 KG
ADR - Tunnel code : E : Passage forbidden through tunnels of category E.
14.2. Sea transport (IMDG) [English only]
Proper shipping name : CYANIDES, INORGANIC, SOLID, N.O.S.
UN N° : 1588
IMO-IMDG - Class or division : 6.1 : Toxic substances.
IMO-IMDG - Packing group : III
IMO- IMDG - Packing instructions : P002 LP02
IMO-IMDG - Limited quantities : 5 kg
IMO-IMDG - Marine pollution : No
EMS-Nr : F-A S-A
14.3. Air transport (ICAO-IATA) [English only]
Proper shipping name : CYANIDES, INORGANIC, SOLID, N.O.S.
UN N° : 1588
IATA - Class or division : 6.1 : Toxic substances.
IATA - Packing group : III
IATA - Passenger and Cargo Aircraft : ALLOWED
- Passenger and Cargo - Packing : 670
instruction
- Passenger and Cargo - Maximum : 100 kg
Quantity/Packing
IATA - Cargo only : ALLOWED
- Cargo only - Packing instruction : 677
- Cargo only - Maximum Quantity/ : 200 kg
Packing
IATA - Limited Quantites : 10 kg
ERG-Nr : 6L
15.1. Safety, health and environmental regulations/legislation specific for the
substance or mixture
Safety, health and environmental : Ensure all national/local regulations are observed.
regulations/legislation specific for the substance or mixture
REACH Restrictions - Annex XVII : The components of this product are not subject to
restrictions.
REACH Authorisation - Annex XIV : The components of this product are not subject
to authorization.
15.2. Chemical Safety Assessment
Chemical Safety Assessment : It has not been carried out.
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
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