FOLIN & CIOCATEUS PHENOL REAGENT
- Part number
- RXSOL-60-6604-606
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Folin & Ciocalteu's phenol reagent is used to determine protein concentrations between 1 to 100 μg/mL. However, the reagent exhibits a linear response to protein concentration up to 1000 μg/mL when used according to the instructions for kit Product No. TP0200.
Applications
The Folin–Ciocâlteu reagent (FCR) or Folin's phenol reagent or Folin–Denis reagent, also called the gallic acid equivalence method (GAE), is a mixture of phosphomolybdate and phosphotungstate used for the colorimetric in vitro assay of phenolic and polyphenolic antioxidants.
Dosage and directions
The Folin–Ciocalteu reagent which is a mixture of tungstates and molybdates works on the mechanism of oxidation–reduction reaction. The method strongly relies on the reduction of the mixture heteropolyphosphotungsates–molybdates by the phenolic compound which results in the formation of blue coloured chromogen.
Characteristics and notes
The Folin-Ciocalteu (F-C) Assay was developed in 1927 for the measurement of tyrosine (1). The reagent consists of a mixture of sodium molybdate, sodium tungstate and other reagents. Upon reaction with phenols, it produces a blue color which absorbs at 765 nm.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name |
|
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| Product Type | FOLIN & CIOCALTEU'S PHENOL REAGENT VER | |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation : Preparation.
Hazardous component(s) : This product is hazardous.
Substance name Contents CAS No
SODIUM TUNGSTATE : > 10 < 15 % 10213-10-2
DIHYDRATE) Molibdato de sodio dihidrato : > 1 < 5 % 10102-40-6
Hydrochloric acid : > 1 < 5 % 7647-01-0
Phosphoric acid : > 1 < 5 % 7664-38-2
LITHIUM SULPHATE AR : > 15 < 25 % 10102-25-7
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Classification : Xn; R22
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Health hazards : Skin corrosion - Category 1B - Danger (CLP : Skin Corr. 1B) H314
Acute toxicity, Oral - Category 4 - Warning (CLP : Acute Tox. 4) H302
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Symbol(s) : Xn : Harmful
R Phrase(s) : R22 : Harmful if swallowed
. R36/38 : Irritating to eyes and skin.
S Phrase(s) : S26 : In the case of contact with eyes, rinse immediately with plenty of
water and seek medical advise.
S35 : This material and its container must be disposed of in a safe way
S36 : Wear suitable protective clothing.
S51 : Use only in well-ventilated areas.
S59 : Refer to manufacturer/supplier for information on recovery/recycling.
Labelling Regulation EC 1272/2008 (CLP)
Hazard pictograms
Signal words : Danger
Hazard statements : H314 : Causes severe skin burns and eye damage
. H302 : Harmful if swallowed.
Precautionary statements
• Prevention : P280: Wear protective gloves, protective clothing, eye protection, face
protection.
P260: Do not breathe dust, fume, gas, mist, vapours, spray.
P264: Wash thoroughly after handling
. P270: Do not eat, drink or smoke when using this product.
• Response : P301+P330+P331: IF SWALLOWED : Rinse mouth. Do NOT induce
vomiting.
P305+P351+P338: IF IN EYES : Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED : Remove to fresh air and keep at rest in a position
comfortable for breathing.
P303+P361+P353: IF ON SKIN (or hair) : Remove immediately all contaminated
clothing. Rinse skin with water/shower.
P363: Wash contaminated clothing before reuse.
• Storage : P405: Store locked up.
• Disposal considerations : P501: Dispose of this material and its container to hazardous
or special waste collection point, in accordance with local, regional, national and/or
international regulation
3..3. Other hazards
Other hazards : The substance does not fulfil the criteria to be identified as PBT
substance or vPvB substance according to Annex XIII of Regulation REACH.
4.1. Description of first aid measures
Inhalation : Immediately call a POISON CENTER or doctor. Remove to fresh air and
keep at rest in a position comfortable for breathing.
Skin contact : Remove/Take off immediately all contaminated clothing. Wash with
plenty of soap and water. Immediately call a POISON CENTER or doctor.
Eye contact : Immediately call a POISON CENTER or doctor. Remove contact lenses, if
present and easy to do. Continue rinsing. Rinse cautiously with water for several minutes.
Ingestion : Do NOT induce vomiting. Rinse mouth. Immediately call a POISON
CENTER or doctor.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use : Causes severe skin burns and eye damage
. Swallowing a small quantity of this material will result in serious health hazard
. 4.3. Indication of any immediate medical attention and special treatment needed
General information : Never give anything by mouth to an unconscious person. If you
feel unwell, seek medical advice (show the label where possible).
.
5.1. Extinguishing media
Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media : Do not use a heavy water stream.
Surrounding fires : Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products : Under fire conditions, hazardous fumes will be
present. Thermal decomposition generates : Corrosive vapours
. 5.3. Advice for fire-fighters
Protection against fire : Do not enter fire area without proper protective equipment,
including respiratory protection
. Special procedures : Exercise caution when fighting any chemical fire. Avoid (reject)
fire-fighting water to enter environment.
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders : Equip cleanup crew with proper protection.
Ventilate area.
Avoid breathing dust, fume, gas, mist, vapours, spray.
For non-emergency personnel : Evacuate unnecessary personnel.
6.2. Environmental precautions
Environmental precautions : Prevent entry to sewers and public waters. Notify
authorities if product enters sewers or public waters.
6.3. Methods and material for containment and cleaning up
Clean up methods : On land, sweep or shovel into suitable containers. Minimize
generation of dust. Store away from other materials.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling : Wash thoroughly after handling. Do not eat, drink or smoke when using this
product. Do not breathe dust, fume, gas, mist, vapours, spray. Wash contaminated
clothing before reuse
. Technical protective measures : Provide good ventilation in process area to prevent
formation of vapour.
7.2. Conditions for safe storage, including any incompatibilities
Storage : Keep only in the original container in a cool, well ventilated place. Keep
container closed when not in use.
Storage regulation : Comply with applicable regulations.
Storage - away from : Strong bases. Strong acids. Sources of ignition. Direct sunlight
. 7.3. Specific end use(s)
Specific end use(s) : None.
8.1. Exposure controls
Personal protection Personal protection : Avoid all unnecessary exposure
. • Respiratory protection : Wear approved mask.
• Hand protection : Wear protective gloves.
• Skin protection : Wear suitable protective clothing.
• Eye protection : Chemical goggles or face shield.
• Others : When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits : No data available.
9.1. Information on basic physical and chemical properties
Physical state at 20 °C : Liquid.
Odour threshold : No data available.
pH value : No data available.
Melting point [°C] : No data available
. Decomposition point [°C] : N/A
Critical temperature [°C] : No data available
. Auto-ignition temperature [°C] : No data available.
Flammability (solid, gas) : N/A
Flash point [°C] : No data available.
Boiling point [°C] : N/A
Initial boiling point [°C] : Nodata available
. Final boiling point [°C] : No data available
. Evaporation rate : N/A
Vapour pressure [20°C] : No data available
. Vapour pressure mm/Hg : 167 mm Hg at 20°C
Vapour density : 3,4
Density [g/cm3] : 1,27
Relative density, gas (air=1) : N/A
Relative density, liquid (water=1) : N/A
Solubility in water [% weight] : Soluble in water
Solubility in water : No data available
. Log Pow octanol / water at 20°C : No data available .
Solubility : < 0.5 at 20 °C
Viscosity at 40°C [mm2/s] : No data available.
9.2. Other information
Explosive properties : N/A
Explosion limits - upper [%] : No data available.
Explosion limits - lower [%] : No data available.
Oxidising properties : No data available.
10.1. Reactivity
Reactivity : Not established.
10.2. Chemical stability
Chemical stability : Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions : Not established.
10.4. Conditions to avoid
Conditions to avoid : Direct sunlight. Extremely high or low temperatures.
10.5. Incompatible materials
Materials to avoid : Strong acids. Strong bases.
10.6. Hazardous decomposition products
Hazardous decomposition products : Fumes. Carbon monoxide. Carbon dioxide.
Thermal decomposition generates : Corrosive vapours.
11.1. Information on toxicological effects
Toxicity information : The product has been not fully tested. The calculated risk has
been done under the requirements of the EU regulations.
Acute toxicity
• Inhalation : Based on available data, the classification criteria are not met.
• Dermal : Based on available data, the classification criteria are not met.
• Ingestion : Based on available data, the classification criteria are not met.
Corrosion : Based on available data, the classification criteria are not met.
Irritation : Based on available data, the classification criteria are not met.
Sensitization : Based on available data, the classification criteria are not met
. Mutagenicity : Based on available data, the classification criteria are not met.
Carcinogenicity : Based on available data, the classification criteria are not met.
Toxic for reproduction : Based on available data, the classification criteria are not met.
STOT-single exposure : Causes damage to organ. Causes damage to organ
. STOT-repeated exposure : Based on available data, the classification criteria are not met.
Aspiration hazard : Based on available data, the classification criteria are not met.
12.1. Toxicity
Toxicity information : The product has been not fully tested. The calculated risk has
been done under the requirements of the EU regulations.
12.2. Persistence - degradability
Persistence - degradability : Biodegradable
12.3. Bioaccumulative potential
Bioaccumulative potential : Not established.
12.4. Mobility in soil
Mobility in soil : Not established.
12.5. Results of PBT and vPvB assessment
Results of PBT and vPvB assessment : The substance does not fulfil the criteria to be
identified as PBT substance or vPvB substance according to Annex XIII of Regulation
REACH.
12.6. Other adverse effects
Environmental precautions : Avoid release to the environment
13.1. Waste treatment methods
General : Avoid release to the environment. Dispose in a safe manner in accordance with
local/national regulations
. Dispose of this material and its container to hazardous or
special waste collection point, in accordance with local, regional, national and/or
international regulation.
14.1. Land transport (ADR-RID)
Proper shipping name : CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S
. UN N° : 3264
H.I. nr : 80
ADR - Class : 8
Labelling - Transport : 8 : Corrosive substance.
ADR - Classification code : C1
ADR - Group : III
ADR - Packing instructions : P001 R001 LP001
ADR - Limited Quantity : 5 L
ADR - Tunnel code : E : Passage forbidden through tunnels of category E
14.2. Sea transport (IMDG) [English only]
Proper shipping name : CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S.
UN N° : 3264
IMO-IMDG - Class or division : 8 : Corrosive substance.
IMO-IMDG - Packing group : III
IMO- IMDG - Packing instructions : P001 LP01
IMO-IMDG - Limited quantities : 5 L
IMO-IMDG - Marine pollution : Yes
EMS-Nr : F-A S-B
14.3. Air transport (ICAO-IATA) [English only]
Proper shipping name : CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S
. UN N° : 3264
IATA - Class or division : 8 : Corrosive substance.
IATA - Packing group : III
IATA - Passenger and Cargo Aircraft : ALLOWED
- Passenger and Cargo - Packing : 852
instruction
- Passenger and Cargo - Maximum : 5 L
Quantity/Packing
IATA - Cargo only : ALLOWED
- Cargo only - Packing instruction : 856
- Cargo only - Maximum Quantity/ : 60 L
Packing
IATA - Limited Quantites : 1 L
ERG-Nr : 8L
15.1. Safety, health and environmental regulations/legislation specific for the
substance or mixture
Safety, health and environmental : Ensure all national/local regulations are observed
. regulations/legislation specific for the substance or mixture
REACH Restrictions - Annex XVII : The components of this product are not subject to
restrictions.
REACH Authorisation - Annex XIV : The components of this product are not subject to
authorization.
15.2. Chemical Safety Assessment Chemical Safety Assessment : It has not been carried out
.
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None. In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP
Regulation (CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
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