FORMAMIDE LR 98%
It is chemical feedstock for the manufacture of sulfa drugs, other pharmaceuticals, herbicides, pesticides and the manufacture of hydrocyanic acid.
- Part number
- RXSOL-60-6604-610
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Formamide is a constituent of cryoprotectant vitrification mixtures used for cryopreservation of tissues and organs. Formamide is also used as an RNA stabiliser in gel electrophoresis by deionizing RNA. In capillary electrophoresis, it is used for stabilizing (single) strands of denatured DNA.
Applications
It is chemical feedstock for the manufacture of sulfa drugs, other pharmaceuticals, herbicides, pesticides and the manufacture of hydrocyanic acid.
Formamide is a formic acid amide that is used widely, for example as an intermediate in the agrochemical, pharmaceutical and paper finishing industries.
Formamide,HCONH2,formic acid amide
FormaMide CAS No : 75-12-7
Dosage and directions
It is used in the crystallization of pharmaceuticals, in soil stabilization, as a solvent in inks and as a component of liquid fertilizers.
Characteristics and notes
Reproductive toxicity in Swiss mice, during chronic exposure to formamide (FORM) or dimethylformamide (DMF), was evaluated.
Applications:
- It can be used as the raw material for synthesizing imidazole, pyrimidine, 1, 3, 5-triazine, caffeine as well as the solvents for making spinning of acrylonitrile copolymer and plastic anti-static coating, etc.
- Formamide has active reactive and special dissolving capability. It can be used as the raw material for organic synthesis, paper processing agents, softening agent of fiber industry and animal glue as well as being used as the analytical reagent for measuring the amino acid content of rice. In the field of organic synthesis, it has most application in medicine as well as a lot of applications in other fields such as pesticides, dyes, pigments, fragrances and additives.
- It is also a kind of excellent organic solvent and is mainly applied to the spinning of acrylonitrile copolymers and ion exchange resins and plastics antistatic coating or conductive coating. In addition, it can also be used for separating chlorosilane and purifying grease. Formamide can have various kinds of reactions, in addition to have its three hydrogen atoms participate in the reaction, can also be subject to dehydration, CO removal, the introduction of an amino group, an acyl group and cyclization reaction. Take cyclization as an example, diethyl malonate can have cyclization reaction with formamide to generate the intermediate of vitamin B4, the 4, 6-dihydroxypyrimidine. O-aminobenzoic acid can have cyclization reaction with formamide to generate the quinazolinone-4 which is the intermediate for the synthesis of antiarrhythmic drug phenantrolihne. 3--amino-4-ethoxycarbonyl-pyrazole can have cyclization reaction with formamide to generate the inhibitor of the xanthine oxidase, allopurinol. EDTA can have cyclization reaction with formamide to give anti-cancer drugs ethylenediamine. Methyl ethyl methoxymalonate can have cyclization reaction with formamide to generate the intermediate of sulfonamide drug, 5-methoxy-4, 6-dihydroxy pyrimidine disodium.
- It can be used as analytical reagents, solvents and softening agents as well as being used in organic synthesis.
- It can be applied to medicine and pesticide industry.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name |
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| Product Type | FORMAMIDE LR 98% | |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation : Formamide
CAS No :75-12-7
Substance. Substance name Contents CAS No
Formamide : 100 % 75-12-7
Contains no other components or impurities which will influence the classification of the product.
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Classification : Repr. Cat. 2; R61 Hazard Class and Category Code(s), Regulation (EC) No 1272/2008
(CLP) Health hazards : Reproductive toxicity - Unborn Child - Category 1B - Danger (CLP : Repr. 1B) H360
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Symbol(s) : T : Toxic
R Phrase(s) : R61 : May cause harm to the unborn child.
S Phrase(s) : S53 : Avoid exposure - obtain special instructions before use.
S45 : In case of accident or if you feel unwell, seek medical advice immediately
( show the label when possible).
Labelling Regulation EC 1272/2008 (CLP)
Hazard pictograms
Signal words : Danger
Hazard statements : H360D: May damage the unborn child. Precautionary statements
• General : P201: Obtain special instructions before use.
• Prevention : P281: Use personal protective equipment as required.
• Response : P308+P313: If exposed or concerned : get medical advice.
• Storage : P405: Store locked up.
• Disposal considerations : P501: Dispose of this material and its container to
hazardous or special waste collection point, in accordance with local,
regional, national and/or international regulation.
Special labelling : Restricted to professional users.
3.3. Other hazards
Other hazards : The substance does not fulfil the criteria to be identified as PBT
substance or vPvB substance according to Annex XIII of Regulation REACH.
4.1. Description of first aid measures
Inhalation : Assure fresh air breathing. Allow the victim to rest.
Skin contact : Remove affected clothing and wash all exposed
skin area with mild soap and water, followed by warm water rinse.
Eye contact : Rinse immediately with plenty of water.
Obtain medical attention if pain, blinking or redness persist.
Ingestion : Obtain emergency medical attention. Rinse mouth. Do NOT induce vomiting.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use : May damage the unborn child.
4.3. Indication of any immediate medical attention and special treatment needed
General information : Never give anything by mouth to an unconscious person.
If exposed or concerned : get medical advice.
5.1. Extinguishing media
Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media : Do not use a heavy water stream.
Surrounding fires : Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products : Under fire conditions, hazardous fumes will be present.
5.3. Advice for fire-fighters
Protection against fire : Do not enter fire area without proper protective equipment,
including respiratory protection. Special procedures : Exercise caution when fighting
any chemical fire. Avoid (reject) fire-fighting water to enter environment.
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders : Equip cleanup crew with proper protection. Ventilate area.
For non-emergency personnel : Evacuate unnecessary personnel.
6.2. Environmental precautions
Environmental precautions : Prevent entry to sewers and public waters.
Notify authorities if product enters sewers or public waters.
6.3. Methods and material for containment and cleaning up
Clean up methods : Soak up spills with inert solids, such as clay or diatomaceous
earth as soon as possible. Store away from other materials. Collect spillage.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling : Wash hands and other exposed areas with mild soap
and water before eat, drink or smoke and when leaving work.
Obtain special instructions before use.
Technical protective measures : Provide good ventilation in process
area to prevent formation of vapour.
7.2. Conditions for safe storage, including any incompatibilities
Storage : Keep only in the original container in a cool, well ventilated place.
Keep container closed when not in use. Storage - away from : Strong bases.
Strong acids. Sources of ignition. Direct sunlight.
7.3. Specific end use(s)
Specific end use(s) : None.
8.1. Exposure controls
Personal protection : Avoid all unnecessary exposure.
• Respiratory protection : Wear approved mask.
• Hand protection : Wear protective gloves.
• Eye protection : Chemical goggles or safety glasses.
• Others : When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits : No data available.
9.1. Information on basic physical and chemical properties
Physical state at 20 °C : Liquid.
Odour threshold : No data available.
pH value : No data available.
Melting point [°C] : 2 - 3 °C
Decomposition point [°C] : N/A
Critical temperature [°C] : N/A
Auto-ignition temperature [°C] : N/A
Flammability (solid, gas) : N/A
Flash point [°C] : 150 °C
Boiling point [°C] : 210 °C
Initial boiling point [°C] : N/A
Final boiling point [°C] : N/A
Evaporation rate : N/A
Vapour pressure [20°C] : 0.11
hPa at 20 °C
Vapour pressure mm/Hg : N/A
Vapour density : 1,56
Density [g/cm3] : 1.134
g/cm3 at 25 °C
Relative density, gas (air=1) : N/A
Relative density, liquid (water=1) : N/A
Solubility in water [% weight] : Completely miscible
Solubility in water : N/A
Log Pow octanol / water at 20°C : No data available.
Solubility : 7.1 at 23
g/l Viscosity at 40°C [mm2/s] : N/A
9.2. Other information
Explosive properties : N/A
Explosion limits - upper [%] : 19%
Explosion limits - lower [%] : 2,70%
Oxidising properties : No data available.
10.1. Reactivity
Reactivity : Not established.
10.2. Chemical stability
Chemical stability : Stable under
recommended storage conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions : Not established.
10.4. Conditions to avoid
Conditions to avoid : Direct sunlight.
Extremely high or low temperatures.
10.5. Incompatible materials
Materials to avoid : Strong acids. Strong bases.
10.6. Hazardous decomposition products
Hazardous decomposition products : Fumes.
Carbon monoxide. Carbon dioxide.
11.1. Information on toxicological effects Acute toxicity
• Inhalation : Based on available data, the classification criteria are not met.
• Dermal : Based on available data, the classification criteria are not met.
• Ingestion : Based on available data, the classification criteria are not met.
Corrosion : Based on available data, the classification criteria are not met.
Irritation : Based on available data, the classification criteria are not met.
Sensitization : Based on available data, the classification criteria are not met.
Mutagenicity : Based on available data, the classification criteria are not met.
Carcinogenicity : Based on available data, the classification criteria are not met.
Toxic for reproduction : May damage the unborn child.
STOT-single exposure : Based on available data, the classification criteria are not met.
STOT-repeated exposure : Based on available data, the classification criteria are not met.
Aspiration hazard : Based on available data, the classification criteria are not met.
12.1. Toxicity
Toxicity information : Not established.
12.2. Persistence - degradability
Persistence - degradability : Biodegradable.
12.3. Bioaccumulative potential
Bioaccumulative potential : Not established.
12.4. Mobility in soil
Mobility in soil : Not established.
12.5. Results of PBT and vPvB assessment
Results of PBT and vPvB assessment : The substance
does not fulfil the criteria to be identified as PBT substance
or vPvB substance according to Annex XIII of Regulation REACH.
12.6. Other adverse effects
Environmental precautions : Avoid release to the environment.
13.1. Waste treatment methods
General : Avoid release to the environment.
Dispose in a safe manner in accordance with
local/national regulations. Dispose of this material
and its container to hazardous or special waste collection
point, in accordance with local, regional, national and/or international regulation.
14.1. Land transport (ADR-RID)
General information : Not regulated.
14.2. Sea transport (IMDG) [English only]
General information : Not regulated.
14.3. Air transport (ICAO-IATA) [English only]
General information : Not regulated.
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
Safety, health and environmental : Ensure all national/local regulations are observed.
regulations/legislation specific for the substance or mixture REACH Restrictions - Annex XVII : With the
exception of those listed below: The components of this product are not subject to restrictions.
REACH Authorisation - Annex XIV : The components of this product are not subject to authorization.
15.2. Chemical Safety Assessment
Chemical Safety Assessment : It has not been carried out.
.
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic. vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL
of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 Further information : None. In accordance with REACH
Regulation (CE) Nº 1907/2006 and with CLP Regulation (CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
FORMAMIDE LR 98% manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
FORMAMIDE LR 98% is available in small packing as well as in bulk. Buy premium quality FORMAMIDE LR 98% and other lab chemicals from one of the most trusted brands.
