GLYCINE Pharma Grade
Glycine is a non-polar, hydrophobic, non-essential αamino acid. It is the simplest and smallest amino acid among all the amino acids and is chemically neutral in nature.
- Part number
- RXSOL-19-6604-125
- Category
- Medicine
- Brand
- RXSOL
Overview
Glycine is a non-polar, hydrophobic, non-essential αamino acid. It is the simplest and smallest amino acid among all the amino acids and is chemically neutral in nature. It is used as a component of many animal and insect cell culture media. Some major functions of Glycine in cell culture involve synthesis of proteins in the cells. Hence it is also called proteinogenic amino acid. It also contributes towards cellular purine synthesis.
Technical specifications
| Molecular Weight | 75.07 |
|---|---|
| Molecular Formula | C2H5NO |
| CAS No | 56-40- |
| Synonym | Aminoacetic acid, Aminoethanoic acid, Glycocoll |
Applications
Glycine has buffering capacity and hence acts as an osmoprotectant for cells in culture. It participates in majority of anabolic reaction such as synthesis of heme, creatine and glutathione. Besides these, the glycine cleavage pathway is found to be associated with cell proliferation of several human tumor cell lines. Presence of glycine in conditioned medium enhances the growth of mouse and cattle embryos. Since glycine acts as an inhibitory neurotransmitter in brain and spinal cord, it is a prime target of many neuro psycho pharmacologic agents.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Type | GLYCINE Pharma Grade |
| Product Code | RXSOL-19-6604-125 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation : GLYCINE AR
CAS No :56-40-6
Substance.
Contains no other components or impurities which will influence the classification of the product.
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Not classified.
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not classified.
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Not classified.
S Phrase(s) : S22 : Do not breathe dust.
S24/25 : Avoid contact with skin and eyes.
Labelling Regulation EC 1272/2008 (CLP)
Not classified.
3.3. Other hazards
Other hazards : The substance does not fulfil the criteria to be identified as PBT substance or vPvB substance according to Annex XIII of Regulation REACH.
4.1. Description of first aid measures
Inhalation : Assure fresh air breathing. Allow the victim to rest.
Skin contact : Remove affected clothing and wash all exposed skin area with mild soap
and water, followed by warm water rinse.
Eye contact : Rinse immediately with plenty of water. Obtain medical attention if pain,
blinking or redness persist.
Ingestion : Obtain emergency medical attention. Rinse mouth. Do NOT induce vomiting.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use : Not expected to present a significant hazard under
anticipated conditions of normal use.
4.3. Indication of any immediate medical attention and special treatment needed
General information : Never give anything by mouth to an unconscious person. If you
feel unwell, seek medical advice (show the label where possible).
5.1. Extinguishing media
Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media : Do not use a heavy water stream.
Surrounding fires : Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products : Under fire conditions, hazardous fumes will be
present.
5.3. Advice for fire-fighters
Protection against fire : Do not enter fire area without proper protective equipment,
including respiratory protection.
Special procedures : Exercise caution when fighting any chemical fire. Avoid (reject)
fire-fighting water to enter environment.
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders : Equip cleanup crew with proper protection.
Ventilate area.
For non-emergency personnel : Evacuate unnecessary personnel.
6.2. Environmental precautions
Environmental precautions : Prevent entry to sewers and public waters. Notify
authorities if product enters sewers or public waters.
6.3. Methods and material for containment and cleaning up
Clean up methods : On land, sweep or shovel into suitable containers. Minimize
generation of dust. Store away from other materials.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling : Wash hands and other exposed areas with mild soap and water before eat,
drink or smoke and when leaving work.
Technical protective measures : Provide good ventilation in process area to prevent
formation of vapour.
7.2. Conditions for safe storage, including any incompatibilities
Storage : Keep only in the original container in a cool, well ventilated place. Keep
container closed when not in use.
Storage - away from : Strong bases. Strong acids. Sources of ignition. Direct sunlight.
7.3. Specific end use(s)
Specific end use(s) : None
8.1. Exposure controls
Personal protection : Avoid all unnecessary exposure.
• Respiratory protection : Wear approved mask.
• Hand protection : Wear protective gloves.
• Eye protection : Chemical goggles or safety glasses.
• Others : When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits : No data available.
9.1. Information on basic physical and chemical properties
Physical state at 20 °C : Solid.
Odour threshold : No data available.
pH value : Not applicable.
Melting point [°C] : 240 °C
Decomposition point [°C] : N/A
Critical temperature [°C] : N/A
Auto-ignition temperature [°C] : N/A
Flammability (solid, gas) : N/A
Flash point [°C] : N/A
Boiling point [°C] : N/A
Initial boiling point [°C] : N/A
Final boiling point [°C] : N/A
Evaporation rate : N/A
Vapour pressure [20°C] : N/A
Vapour pressure mm/Hg : N/A
Vapour density : N/A
Density [g/cm3] : 1,16
Relative density, gas (air=1) : N/A
Relative density, liquid (water=1) : N/A
Solubility in water [% weight] : 25g/100 ml water @ 2
Solubility in water : N/A
Log Pow octanol / water at 20°C : No data available.
Solubility : 4
Viscosity at 40°C [mm2/s] : N/A
9.2. Other information
Explosive properties : N/A
Explosion limits - upper [%] : N/A
Explosion limits - lower [%] : N/A
Oxidising properties : No data available.
10.1. Reactivity
Reactivity : Not established.
10.2. Chemical stability
Chemical stability : Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions : Not established.
10.4. Conditions to avoid
Conditions to avoid : Direct sunlight. Extremely high or low temperatures.
10.5. Incompatible materials
Materials to avoid : Strong acids. Strong bases.
10.6. Hazardous decomposition products
Hazardous decomposition products : Fumes. Carbon monoxide. Carbon dioxide.
11.1. Information on toxicological effects
Acute toxicity
• Inhalation : Based on available data, the classification criteria are not met.
• Dermal : Based on available data, the classification criteria are not met.
• Ingestion : Based on available data, the classification criteria are not met.
Corrosion : Based on available data, the classification criteria are not met.
Irritation : Based on available data, the classification criteria are not met.
Sensitization : Based on available data, the classification criteria are not met.
Mutagenicity : Based on available data, the classification criteria are not met.
Carcinogenicity : Based on available data, the classification criteria are not met.
Toxic for reproduction : Based on available data, the classification criteria are not met.
STOT-single exposure : Based on available data, the classification criteria are not met.
STOT-repeated exposure : Based on available data, the classification criteria are not
met.
Aspiration hazard : Based on available data, the classification criteria are not met.
12.1. Toxicity
Toxicity information : Not established.
12.2. Persistence - degradability
Persistence - degradability : Biodegradable.
12.3. Bioaccumulative potential
Bioaccumulative potential : Not established.
12.4. Mobility in soil
Mobility in soil : Not established.
12.5. Results of PBT and vPvB assessment
Results of PBT and vPvB assessment : The substance does not fulfil the criteria to be
identified as PBT substance or vPvB substance according to Annex XIII of Regulation
REACH.
12.6. Other adverse effects
Environmental precautions : Avoid release to the environment.
13.1. Waste treatment methods
General : Avoid release to the environment. Dispose in a safe manner in accordance with
local/national regulations.
14.1. Land transport (ADR-RID)
General information : Not regulated.
14.2. Sea transport (IMDG) [English only]
General information : Not regulated.
14.3. Air transport (ICAO-IATA) [English only]
General information : Not regulated.
15.1. Safety, health and environmental regulations/legislation specific for the
substance or mixture
Safety, health and environmental : Ensure all national/local regulations are observed.
regulations/legislation specific for the substance or mixture
REACH Restrictions - Annex XVII : The components of this product are not subject to
restrictions.
REACH Authorisation - Annex XIV : The components of this product are not subject
to authorization.
15.2. Chemical Safety Assessment
Chemical Safety Assessment : It has not been carried out.
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY: The information in this SDS was
obtained from sources which we believe are reliable. However, the information is
provided without any warranty, express or implied, regarding its correctness. The
conditions or methods of handling,storage, use or disposal of the product are beyond our
control and may be beyond our knowledge. For this and other reasons, we do not assume
responsibility and expressly disclaim liability for loss, damage or expense arising out of
or in any way connected with the handling, storage, use or disposal of the product. This
MSDS was prepared and is to be used only for this product. If the product is used as a
component in another product, this MSDS information may not be applicable.
Availability
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