HISTAMINE DIHYDROCHLORIDE not for sale
HISTAMINE DIHYDROCHLORIDE
- Part number
- RXSOL-60-6604-677
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Histamine dihydrochloride is a salt of histamine that is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia.
Applications
Histamine dihydrochloride is a topical analgesic used for minor aches and pains of muscles and joints. It is also being researched as an orphan drug for the adjunctive treatment of acute myeloid leukemia or malignant melanoma. -Apply a thin layer to pain site and massage into skin until thoroughly absorbed.
Dosage and directions
IL-2 is administered twice daily as a subcutaneous injection 1 to 3 minutes prior to the administration of Ceplene; each dose of IL-2 is 16,400 IU/kg (1 µg/kg).
Characteristics and notes
Concentration information is not available for this spectrum and, therefore, molar absorptivity values cannot be derived.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name |
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| Product Type | HISTAMINE DIHYDROCHLORIDE | |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
2.1 Substances : HISTAMINE DIHYDROCHLORIDE
CAS-No. : 56-92-8
Substance name Contents CAS No
Histamine Dihydrochloride 100 % 56-92-8
Substance.
Contains no other components or impurities which will influence the classification of the
product.
3.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Respiratory sensitisation (Category 1), H334
Skin sensitisation (Category 1), H317
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
For the full text of the H-Statements mentioned in this Section, see Section 16.
3.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Symbol(s) : Xn : Harmful
R Phrase(s) : R36/37/38 : Irritating to eyes, respiratory system and skin.
R42/43 : May cause sensitisation by inhalation and skin contact.
S Phrase(s) : S22 :Do not breath dust.
S26 : In the case of contact with eyes, rinse immediately with plenty of water and seek
medical advise.
S36/37/39 : Wear suitable protective clothing and gloves & eye/face protecting.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the
label where possible).
Hazard pictograms
Signal word : Danger
Hazard statement(s): H315 Causes skin irritation.
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335 May cause respiratory irritation.
Precautionary statement(s)
P261 Avoid breathing dust.
P280 Wear protective gloves.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER/doctor.
Supplemental Hazard Statements none
3.3 Other hazards - none
4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see
section 2.2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas
5.3 Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
5.4 Further information No data available
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist
or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing
dust. For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Store at Room Temperature. Storage class (TRGS 510): Combustible Solids
7.3 Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
8.1 Control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands
before breaks and at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved
under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal
technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good
laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy
the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be
selected according to the concentration and amount of the dangerous substance at the
specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle r (US) or type
ABEKP2 (EU EN 143) respirator cartridges. Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.
9.1 Information on basic physical and chemical properties
Odour Threshold: No data available
pH : No data available
Melting point/freezing Point :244 °C
Initial boiling point and boiling range : No data available
Flash point: No data available
Evaporation rate : No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: No data available
Vapour density : No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: noctanol/ water: No data available
Auto-ignition temperature: No data available
Decomposition temperature: No data available
Viscosity : No data available
Explosive properties: No data available
Oxidizing properties: No data available
9.2 Other safety information
No data available
10.1 Reactivity
No data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data available
10.4 Conditions to avoid
No data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides,
Nitrogen oxides (NOx), Hydrogen chloride gas Other decomposition products - No data
available In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - Mouse - 2,534 mg/kg(2-Imidazol-4-ylethylamine dihydrochloride)
Skin corrosion/irritation
No data available(2-Imidazol-4-ylethylamine dihydrochloride)
Serious eye damage/eye irritation
No data available(2-Imidazol-4-ylethylamine dihydrochloride)
Respiratory or skin sensitisation
Germ cell mutagenicity
No data available(2-Imidazol-4-ylethylamine dihydrochloride)
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is
identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available(2-Imidazol-4-ylethylamine dihydrochloride)
Specific target organ toxicity - single exposure
Inhalation - May cause respiratory irritation.(2-Imidazol-4-ylethylamine dihydrochloride)
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available(2-Imidazol-4-ylethylamine dihydrochloride)
Additional Information
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have
not been thoroughly investigated.(2-Imidazol-4-ylethylamine dihydrochloride)
Liver - Irregularities - Based on Human Evidence(2-Imidazol-4-ylethylamine
dihydrochloride)
12.1 Toxicity
No data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available(2-Imidazol-4-ylethylamine dihydrochloride)
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not
conducted
12.6 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or
mix the material with a combustible solvent and burn in a chem scrubber.
Contaminated packaging
Dispose of as unused product.
14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
No data available
15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.2 Chemical safety assessment
For this product a chemical safety assessment was not carried out
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
HISTAMINE DIHYDROCHLORIDE not for sale manufacturer supplier distributor in Mumbai, Kandla, Kolkata, Vizag, Chennai, India, Fujairah, Dubai, Sharjah, UAE, Gulf, Middle East, Muscat Oman, Kenya Africa. Get the best quality of HISTAMINE DIHYDROCHLORIDE not for sale at a competitive price from us. We have ready stock of HISTAMINE DIHYDROCHLORIDE not for sale in India, UAE Gulf, Oman, Kenya Africa. Contact us for bulk as well as small orders.
