RXSOL CHEMO PHARMA International Navi Mumbai, India

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Lab Chemical

IODINE GREEN

Part number
RXSOL-60-6604-731
Category
Lab Chemical
Brand
RXSOL
RXSOL

Overview

IODINE GREEN is a histological dye used for staining chromatin and amyloid. A fluorescent dye used to stain biological specimens. A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm.

Applications

A histological dye used for staining chromatin and amyloid. It has a role as a fluorochrome and a histological dye. It is an iminium salt, an organic chloride salt and a quaternary ammonium salt.

Dosage and directions

  • Adults. 2 mg/kg IV; 5 mg interstitially into the cervix.
  • Geriatric. 2 mg/kg IV; 5 mg interstitially into the cervix.
  • Adolescents. 2 mg/kg IV.
  • Children. 2 mg/kg IV.
  • Infants. 2 mg/kg IV.
  • Neonates.
 
 

Characteristics and notes

A library of 1,3,5-trisubstituted pyrazoles was synthesized in excellent yields from the reaction of aldehyde, phenylhydrazine and alkynes in the presence of iodine via an eco-friendly, simple process performed in aqueous medium. This single pot transformation generates new C[double bond, length as m-dash]N, C–C, C–N bonds and proceeds by a domino reaction involving the formation of Schiff base, Mannich addition and finally intramolecular cyclisation.

Safety and SDS

Read the safety data sheet before handling. Wear suitable gloves and eye protection.

View safety data sheet
Porduct Name              
IODINE GREEN
Part Number   RXSOL-60-6604-731

Company Details:

RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA

Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA  

Phone +91 22 20871200 - 1400
Fax +91 22 27612100 :::AOH :0091 9821214367
Email rxsolchemicals@gmail.com
Website www.rxmraine.com
Chemical Name                 Cas No                        EC No              Whight                          Formula                   
IODINE GREEN          7553-56-2 231-442-4 <= 100 % I2
Signal Word  Danger
Hazard Statements H372 Causes damage to organs through prolonged or repeated exposure if swallowed.
Precautionary statements   P314 Get medical advice/ attention if you feel unwell.
Classification of the substance or mixture Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
Supplemental Hazard      Statements None
Other hazards  This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
General advice Show this material safety data sheet to the doctor in attendance.
If inhaled After inhalation: fresh air. Call in physician.
Eye Contact  After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
Swallowed After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Skin Contact   In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
Most important symptoms and effects, both acute and delaye The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed  No data available
Suitable extinguishing media  Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture  Hydrogen iodide Not combustible. Ambient fire may liberate hazardous vapours.
Further information Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Advice for firefighters Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Enviromental Precaution Do not let product enter drains.
Methods and materials for
containment and cleaning
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Reference to other sections    For disposal see section 13.
Advice on protection against fire and explosion Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.
Hygiene measures Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. For precautions see section 2.2.
Advice on    safe handling Work under hood. Do not inhale substance/mixture.
Storage conditions Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons. Handle and store under inert gas. Hygroscopic.
Storage class Storage class (TRGS 510): 6.1D: Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
Specific end     use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Body Protection protective clothing
Skin protection This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L
Respiratory protection
Recommended Filter type: Filter B-(P2) The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Control of    environmental exposure Do not let product enter drains.
Physical state Solid
Colour Black, Violet
Odour Pungent
pH 5,4
Melting Point 113 °C - lit.
Boiling Point 184 °C - lit.
Flash Point 6 °C - closed cup
Flammability (solid, gas) The product is not flammable.
Upper/lower flammability or explosive limits No data available
Autoignition temperature No data available
Decomposition temperature  No data available
Vapour pressure 0,41 hPa at 25 °C                                              
Viscosity No data available      
Density 4,930 g/cm3 at 20 °C
Relative Density No data available
Partition coefficient No data available
Explosive properties No data available 
Solubility 0,3 g/l at 25 °C - slightly soluble
Particle characteristics No data available 
Reactivity                        No data available
Chemical stability The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions Risk of explosion with: Reducing agents Alkali metals Acetylene Ammonia Potassium copper compounds sodium oxyhalogenic compounds Boron halogen oxides iodides azides ammonium compounds antimony in powder form mercury oxide with Methanol and ethanol Risk of ignition or formation of inflammable gases or vapours with: Powdered metals Zinc semimetals halogen-halogen compounds nonmetals nonmetallic oxides alkali salts Iron Fluorine formaldehyde hydrides sodium phosphite phosphorus sulfur Titanium powdered aluminium acetylidene combustible substances powdered magnesium petrol butadiene Diethyl ether with Aluminum Exothermic reaction with: carbides azides turpentine oils and/or turpentine substitutes alkali oxides lithium silicide alkaline earth compounds nitrides Acetaldehyde Lithium fluorides Oxides of phosphorus Chlorine Iron in powder form
Conditions to avoid no information available                                                                                       
Incompatible materials
No data available
Hazardous decomposition products In the event of fire: see section 5
Acute toxicity  LD50 Oral - Rat - 315 mg/kg (US-EPA) Remarks: The GHS classification specified by the authority LC50 Inhalation - Rat - male and female - 4 h - > 4,588 mg/l - dust/mist (OECD Test Guideline 403) Remarks: (Regulation (EC) No 1272/2008, Annex VI) LD50 Dermal - Rabbit - male and female - 1.425 mg/kg (US-EPA)                    
Skin corrosion/irritation Skin - reconstructed human epidermis (RhE) Result: Moderate skin irritation (Regulation (EC) No. 440/2008, Annex, B.46)
Serious eye      damage/irritation Remarks: Causes serious eye irritation.
Respiratory or skin    sensitization  In animal experiments: - Mouse Result: negative (OECD Test Guideline 429)
Carcinogenicity No data available
Germ cell        mutagenicity  Test Type: Mutagenicity (mammal cell test): Test system: Mouse lymphoma test Metabolic activation: without metabolic activation Method: OECD Test Guideline 476 Result: negative Test Type: In vivo micronucleus test Species: Mouse Application Route: Intraperitoneal Method: Mutagenicity (micronucleus test) Result: negative
Reproductive toxicity  No data available
Specific target organ toxicity - single      exposure
Inhalation - May cause respiratory irritation. - Respiratory system
Additional Information Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Repeated dose toxicity - Rat - female - Oral - 100 d Remarks: (as aqueous solution) Repeated dose toxicity - Rat - male and female - Oral - 29 - 47 d - NOAEL (No observed adverse effect level) - 10 mg/kg RTECS: NN1575000 Prolonged exposure to iodides may produce iodism in sensitive individuals. Symptoms of exposure include: skin rash, running nose, headache and irritation of the mucous membrane. For severe cases the skin may show pimples, boils, hives, blisters and black and blue spots. Iodides are readily diffused across the placenta. Neonatal deaths from respiratory distress secondary to goiter have been reported. Iodides have been known to cause drug-induced fevers, which are usually of short duration., To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. SECTION 12: Ecological inform
Persistence and degradability The methods for determining the biological degradability are not applicable to inorganic substances.
Toxicity to fish  static test LC50 - Oncorhynchus mykiss (rainbow trout) - 1,67 mg/l - 96 h Remarks: (ECHA)
Toxicity to daphnia and other aquatic invertebrates static test EC50 - Daphnia magna (Water flea) - 0,55 mg/l - 48 h Remarks: (ECHA) EC50 - Daphnia magna (Water flea) - 0,2 mg/l - 48 h
Toxicity to bacteria  EC50 - activated sludge - 280 mg/l - 3 h (OECD Test Guideline 209)
Toxicity to algae Growth inhibition ErC50 - Desmodesmus subspicatus (green algae) - 0,13 mg/l - 72 h (OECD Test Guideline 201)
Mobility in soil No data available
Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Endocrine disrupting       properties Assessment : The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Other adverse effects No data available .
Waste treatment      Method See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
UN number ADR/RID:3495              IMDG:3495             IATA: 3495
UN proper shipping name  ADR/RID:IODINE    IMDG:IODINE  IATA:IODINE
Transport hazard class(es)      ADR/RID:8 (6.1)             IMDG:8 (6.1)              IATA:8 (6.1)
Packaging group ADR/RID: III                IMDG:  III     IATA:III
Environmental hazards ADR/RID:   yes                   IMDG: yes                IATA: No
Special precautions for user Tunnel restriction code : (E)
Further information No data available
Safety, health and environmental regulations/legislation specific for the substance or mixture This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
Other regulations Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work.
Chemical Safety Assessment A Chemical Safety Assessment has been carried out for this substance.
Other Information

The information above is believed to be accurate and represents the  best information   currently    available  to us.  However,   we   make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and  weassume  no liability resulting from its use. Users should make  their  own  investigations  to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International  has been advised of the possibility of such damages.

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.

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Availability

[IODINE GREEN] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
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