RXSOL CHEMO PHARMA International Navi Mumbai, India

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Lab Chemical

LEVULINIC ACID

Part number
RXSOL-60-6604-823
Category
Lab Chemical
Brand
RXSOL
RXSOL

Overview

Levulinic acid, or 4-oxopentanoic acid, is an organic compound with the formula CH3C(O)CH2CH2CO2H. 
It is classified as a keto acid. This white crystalline solid is soluble in water and polar organic solvents. 

Applications

Levulinic acid is used as a precursor for pharmaceuticals, plasticizers, and various other additives. The largest application of levulinic acid is its use in the production of aminolevulinic acid, a biodegradable herbicide used in South Asia. Another key application is the use of levulinic acid in cosmetics.

Dosage and directions

Levulinic acid and its derivatives, like sodium levulinate, are used in organic and natural cosmetic compositions for perfuming, skin conditioning and pH-regulating purposes. They give inherent fresh odor, prevent wrinkles and stabilize formulations and emulsions.

Characteristics and notes

Levulinic acid and its derivatives, like sodium levulinate, are used in organic and natural cosmetic compositions for perfuming, skin conditioning and pH-regulating purposes. They give inherent fresh odor, prevent wrinkles and stabilize formulations and emulsions.

Safety and SDS

Read the safety data sheet before handling. Wear suitable gloves and eye protection.

View safety data sheet
Product Name               LEVULINIC ACID
Part Number   RXSOL-60-6604-823

Company Details:

RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA

Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA  

Phone +91 22 20871200 - 1400
Fax +91 22 27612100 :::AOH :0091 9821214367
Email rxsolchemicals@gmail.com
Website www.rxmraine.comA
Chemical  Name                            CAS                    EC number              Weight             Formula 
Levulinic acid 123-76-2 204-649-2 <= 100 %        C5H8O3 
Signal Word  Danger
Hazard Statements H302 Harmful if swallowed. H317 May cause an allergic skin reaction. H318 Causes serious eye damage.
Precautionary statements   P261 Avoid breathing dust. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ eye protection/ face protection. P301 + P312 IF SWALLOWED: Call a POISON CENTER/ doctor if you feel unwell. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Classification of the substance or mixture Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.
Supplemental Hazard      Statements None.
Other hazards  This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
General advice Show this material safety data sheet to the doctor in attendance.
If inhaled  After inhalation: fresh air.
Eye Contact After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
Swallowed After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Skin Contact In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
Inhalation Remove patient to fresh air, keep warm and at rest and get medical assistance in necessary. 
Ingestion Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms and effects, both acute and delaye The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11
Indication of any immediate medical attention and special treatment needed  No data available
Flammability                                                  Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Flash Point Dry powder Dry sand
Suitable extinguishing media Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media For this substance/mixture no limitations of extinguishing agents are given.
Special hazards arising from the substance or mixture  Carbon oxides Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.
Further information Prevent fire extinguishing water from contaminating surface water or the ground water system.
Hazardous combustion
products
Fire may cause the evolution of Sulphur oxides, nitrogen oxides.
Advice for firefighters Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Protective Equipment Use personal protective equipment.
Specific Hazards Arising from the Chemical Oxides of phosphorus Sodium oxides Not combustible. Fire may cause evolution of: Oxides of phosphorus Ambient fire may liberate hazardous vapours.
Personal precautions, protective equipment and emergency procedures Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
Spillage Oxidizing material. Stop leak if without risk. Avoid contact with a combustible material (wood, paper, oil, clothing...). Keep substance damp using water spray. Do not touch spilled material. Prevent entry into sewers, basements or confined areas dike if needed. Eliminate all ignition sources. Call for assistance on disposal.
Enviromental Precaution Do not let product enter drains.
Methods and materials for
containment and cleaning
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Advice on protection against fire and explosion Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Incompatible materials  Keep away from alkalis, strong oxidizing agents and metals. Provide containment walls of adequate capacity to hold any accidental spills. 
Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. For precautions see section 2.2.
Precautions for     safe handling For precautions see section 2.2..
Storage conditions Tightly closed. Dry. Light sensitive.
Storage class Storage class (TRGS 510): 13: Non Combustible Solids
Specific end     use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated
Advice on general occupational hygiene Advice on safe handling Observe label precautions. Change contaminated clothing. Wash hands after working with substance.
Requirements for storage  Keep in cool and store under shade. 
Exposure controls  Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. 
Control parameters Ingredients with workplace control parameters Contains no substances with occupational exposure limit values.
Engineering Control Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles
Body Protection Protective clothing
Skin protection This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L
Respiratory protection Required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P2 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Other Protection      Measure Handle in accordance with good industrial hygiene and safety practice.
Control of    environmental exposure Do not let product enter drains.
Physical state Solid
Colour No data available
Odour No data available
Odor Threshold No data available
pH No data available
Melting Point 30 - 33 °C - lit.
Boiling Point 245 - 246 °C - lit.
Flash Point 98 °C - closed cup
Evaporation Rate Not Applicable
Flammability (solid, gas) No data available
Explosive limits No Data Available
Upper/lower flammability or explosive limits No data available
Autoignition temperature No data available
Decomposition temperature  No data available
Vapour pressure 1 hPa at 102 °C
Density 1,134 g/mL at 25 °C - lit.                                                              
Relative  Density                                                     1,14 at 20 °C
Relative vapor density No data available
Freezing point  No data available 
Viscosity No data available
Partition coefficient log Pow: -0,497 at 20 °C
Explosive properties No data available 
Solubility 791,3 g/l at 20 °C
Ignition temperature No information available.
Particle characteristics No data available 
Reactivity                        Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Stability The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions Violent reactions possible with: Bases Oxidizing agents Reducing agents
Conditions to avoid Strong heating.
Incompatible materials No data available
Hazardous decomposition products In the event of fire: see section 5
Acute toxicity  LD50 Oral - Rat - female - 300 - 2.000 mg/kg (OECD Test Guideline 423) Inhalation: No data available LD50 Dermal - Rat - male and female - > 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation Skin - In vitro study Result: negative (OECD Test Guideline 439)
Serious eye      damage/eye       irritation  Eyes - Bovine cornea Result: Causes serious eye damage. (OECD Test Guideline 437)
Respiratory or skin    sensitization  Local lymph node assay (LLNA) - Mouse Result: positive (OECD Test Guideline 442B)
Toxic Effects on         Human May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer).
Carcinogenicity No data available
Germ cell        mutagenicity  Test Type: Chromosome aberration test in vitro Test system: Human lymphocytes Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473 Result: negative Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster lung cells Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476 Result: negative
Reproductive toxicity  No data available
Specific target organ toxicity - single      exposure No data available
Endocrine disrupting properties The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: OI1575000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Bioaccumulative potential No data available
Persistence and            degradability Biodegradability aerobic - Exposure time 28 d Result: > 60 % - Readily biodegradable. (OECD Test Guideline 301F)
Toxicity to fish  No data available
Toxicity to daphnia and other aquatic invertebrates Static test EC50 - Daphnia - 108,82 mg/l - 48 h Remarks: (ECHA)
Toxicity to algae IC50 - Desmodesmus subspicatus (green algae) - 46,7 mg/l - 72 h Remarks: (IUCLID) (butyric acid)
Toxicity to bacteria  EC50 - activated sludge - > 261 mg/l - 30 min Remarks: (ECHA)
Mobility in soil No Information available
Results of PBT and vPvB assessment This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Endocrine disrupting       properties The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
Other adverse effects No data available
Disposal methods The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging Dispose of as unused product.
Waste treatment      Method See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.
UN number ADR/RID:                    IMDG:                IATA: 
UN proper shipping name ADR/RID:                    IMDG:                IATA:  
Transport hazard class(es) ADR/RID:                    IMDG:                IATA: 
Packaging group ADR/RID:                    IMDG:                IATA:  
Environmental hazards ADR/RID:  NO            IMDG: NO          IATA: NO
Further information No data available                                                                                                                                  
Safety, health and environmental regulations/legislation specific for the substance or mixture This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006.
Other regulations Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work.
Chemical Safety Assessment For this product a chemical safety assessment was not carried out
Other Information

The information above is believed to be accurate and represents the  best information   currently    available  to us.  However,   we   make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and  weassume  no liability resulting from its use. Users should make  their  own  investigations  to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International  has been advised of the possibility of such damages.

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.

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Availability

LEVULINIC ACID  manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
LEVULINIC ACID  is available in small packing as well as in bulk. Buy premium quality LEVULINIC ACID  and other lab chemicals from one of the most trusted brands.

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