MONOTHIOGLYCEROL AR 98%
- Part number
- RXSOL-60-6605-010
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
monothioglycerol ar 98 is a viscous colorless to slightly yellowish hygroscopic liquid. It smells a bit sulfurous.
Applications
Dosage and directions
Standard dosing regimen: initial intravenous bolus dose of 6.5 mg/kg ... are highly protein bound (approximately 98%), primarily to albumin.
Characteristics and notes
The present invention relates to processes for purifying high-quality recombinant Plasmodium falciparum circumsporozoite protein at high yields. This process provides rCSP at high yields without the need for denaturing and refolding the protein. The present invention overcomes obstacles previously encountered in the field, including dimerization, aggregation, and N-terminal degradation of rCSP.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | RXSOL-60-6605-010 |
| Product Type | MONOTHIOGLYCEROL 98% |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation : MONOTHIOGLYCEROL 98%
CAS No : 96-27-5
Substance.
Contains no other components or impurities which will influence the classification of the
product.
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Classification : T+; R26
Xi; R36/37/38
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Health hazards : Specific Target Organ Toxicity - Single exposure - Respiratory tract
irritation - Category 3 - Warning (CLP : STOT SE 3) H335
Acute toxicity, Inhalation - Category 2 - Danger (CLP : Acute Tox. 2) H330
Eye irritation - Category 2A - Warning (CLP : Eye Irrit. 2) H319
Skin irritation - Category 2 - Warning (CLP : Skin Corr. 2) H315
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Symbol(s) : T+ : Very toxic
Xi : Irritant
R Phrase(s) : R26 : Very toxic by inhalation.
R36/37/38 : Irritating to eyes, respiratory system and skin.
S Phrase(s) : S22 : Do not breathe dust.
S24/25 : Avoid contact with skin and eyes.
S36 : Wear suitable protective clothing.
Labelling Regulation EC 1272/2008 (CLP)
Hazard pictograms:
Signal words : Danger
Hazard statements : H330 : Fatal if inhaled.
H319 : Causes serious eye irritation.
H315 : Causes skin irritation.
H335 : May cause respiratory irritation.
Precautionary statements
• Prevention : P284: Wear respiratory protection.
P280: Wear protective gloves, protective clothing, eye protection, face protection.
P271: Use only outdoors or in a well-ventilated area.
P260: Do not breathe dust, fume, gas, mist, vapours, spray.
P264: Wash thoroughly after handling.
• Response : P302+P352: IF ON SKIN : Wash with plenty of soap and water.
P332+P313: If skin irritation occurs : Get medical advice.
P305+P351+P338: IF IN EYES : Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED : Remove to fresh air and keep at rest in a position
comfortable for breathing.
P363: Wash contaminated clothing before reuse.
• Storage : P403+P233: Store in well-ventilated place. Keep container tightly closed.
P405: Store locked up.
• Disposal considerations : P501: Dispose of this material and its container to hazardous
or special waste collection point, in accordance with local, regional, national and/or
international regulation.
3.3. Other hazards
Other hazards : The substance does not fulfil the criteria to be identified as PBT
substance or vPvB substance according to Annex XIII of Regulation REACH
4.1. Description of first aid measures
Inhalation : Specific treatment is urgent (see on this label). Immediately call a POISON
CENTER or doctor. Remove to fresh air and keep at rest in a position comfortable
for breathing.
Skin contact : Specific treatment (see on this label). Wash contaminated clothing before
reuse. Wash with plenty of soap and water. If skin irritation occurs : Get medical advice.
Eye contact : Rinse cautiously with water for several minutes. Get medical advice.
Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation
persists
: Ingestion : Obtain emergency medical attention. Rinse mouth. Do NOT induce vomiting
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use : Fatal if inhaled.
Causes serious eye irritation. Causes skin irritation. May cause respiratory irritation.
4.3. Indication of any immediate medical attention and special treatment needed
General information : Never give anything by mouth to an unconscious person. If you
feel unwell, seek medical advice (show the label where possible)
5.1. Extinguishing media
Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media : Do not use a heavy water stream.
Surrounding fires : Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products : Under fire conditions, hazardous fumes will be
present.
5.3. Advice for fire-fighters
Protection against fire : Do not enter fire area without proper protective equipment,
including respiratory protection.
Special procedures : Exercise caution when fighting any chemical fire. Avoid (reject)
fire-fighting water to enter environment
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders : Equip cleanup crew with proper protection.
Ventilate area.
For non-emergency personnel : Evacuate unnecessary personnel.
6.2. Environmental precautions
Environmental precautions : Prevent entry to sewers and public waters. Notify
authorities if product enters sewers or public waters.
6.3. Methods and material for containment and cleaning up
Clean up methods : Soak up spills with inert solids, such as clay or diatomaceous earth
as soon as possible. Store away from other materials. Collect spillage.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling : Do not breathe dust, fume, gas, mist, vapours, spray.
Wash thoroughly after handling. Use only outdoors or in a well-ventilated area.
Wash thoroughly after handling. Wash thoroughly after handling.
Technical protective measures : Provide good ventilation in process area to prevent
formation of vapour.
Special precautions : Avoid breathing dust, fume, gas, mist, vapours, spray.
7.2. Conditions for safe storage, including any incompatibilities
Storage : Keep only in the original container in a cool, well ventilated place. Keep
container tightly closed.
Storage - away from : Strong bases. Strong acids. Sources of ignition. Direct sunlight.
7.3. Specific end use(s)
Specific end use(s) : None.
8.1. Exposure controls
Personal protection : Avoid all unnecessary exposure
. • Respiratory protection : Wear respiratory protection.
• Hand protection : Wear protective gloves.
• Skin protection : Wear suitable protective clothing.
• Eye protection : Chemical goggles or safety glasses
. • Others : When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits : No data available..
9.1. Information on basic physical and chemical properties
Physical state at 20 °C : Liquid.
Odour : Stench odour Odour threshold : No data available
. pH value : No data available.
Melting point [°C] : No data available.
Decomposition point [°C] : N/A
Critical temperature [°C] : N/A
Auto-ignition temperature [°C] : N/A
Flammability (solid, gas) : N/A
Flash point [°C] : 113 °C
Boiling point [°C] : 118 °C
Initial boiling point [°C] : N/A
Final boiling point [°C] : N/A
Evaporation rate : N/A
Vapour pressure [20°C] : N/A
Vapour pressure mm/Hg : N/A
Vapour density : N/A
Density [g/cm3] : 1,247
Relative density, gas (air=1) : N/A
Relative density, liquid (water=1) : N/A
Solubility in water [% weight] : Slightly soluble in Solubility in water : N/A Log Pow octanol / water at 20°C : No data available. Solubility : N/A
Viscosity at 40°C [mm2/s] : N/A
9.2. Other information
Explosive properties : N/A
Explosion limits - upper [%] : N/A
Explosion limits - lower [%] : N/A
Oxidising properties : No data availableble
.
10.1. Reactivity
Reactivity : Highly reactive material.
10.2. Chemical stability
Chemical stability : Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions : Contact with water liberates toxic gas.
10.4. Conditions to avoid
Conditions to avoid : Direct sunlight. Extremely high or low temperatures.
10.5. Incompatible materials
Materials to avoid : Strong acids. Strong bases.
10.6. Hazardous decomposition products
Hazardous decomposition products : Fumes. Carbon monoxide. Carbon dioxide.
Routes of Entry
: Absorbed through skin. Dermal contact. Eye contact. Ingestion.
Toxicity to Animals
: Acute oral toxicity (LD50): 670 mg/kg [Rat]. Acute dermal toxicity (LD50): 699.3 mg/kg
[Rabbit].
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans:
Hazardous in case of skin contact (irritant, permeator), of inhalation. Slightly hazardous
in case of ingestion.
Special Remarks on Toxicity to Animals:
Not available.
Special Remarks on Chronic Effects on Humans:
May affect genetic material (mutagenic). May cause adverse reproductive effects based
on animal test data. No human data found
Special Remarks on other Toxic Effects on Humans:
Potential Health Effects:
Skin: Prolonged or repeated exposure may cause severe skin irritation. A single
prolonged exposure may result in the material being absorbed in harmul amounts.
Prolonged or repeated skin contact which causes the material to be absorbed through
the skin may affect the thyroid. Eyes: May cause moderate eye irritation. Corneal injury is
unlikely.
Inhalation: Mists may cause irritation of the upper respiratory tract (nose and throat).
Symptoms may include burning senstation, coughing, wheezing, laryngitis, shortness of
breath, headache, nausea, and vomiting. Ingestion: Single dose oral toxicity is considered
to be low. Small amounts swallowed incidental to normal handling operations are not
likely to cause injury; swallowing amounts larger than that may cause injury. May cause
nausea and vomiting. May affect behavior/central nervous system (convulsions, ataxia).
Prolonged or repeated ingestion may affect thyroid.
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation
:Possibly hazardous short term degradation products are not likely. However, long term
degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic
than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
13.1. Waste treatment methods
General : Avoid release to the environment. Dispose in a safe manner in accordance with
local/national regulations.
Dispose of this material and its container to hazardous or special waste collection
point, in accordance with local, regional, national and/or international regulation.
Special precautions : Hazardous waste due to toxicity
14.1. Land transport (ADR-RID)
Proper shipping name : TOXIC LIQUID, ORGANIC, N.O.S.
UN N° : 2810
H.I. nr : 60
ADR - Class : 6.1
Labelling - Transport : 6.1 : Toxic substances.
ÉL ADR - Classification code : T1
T1 ADR - Group : III
ADR - Packing instructions : P001 R001 LP001
ADR - Limited Quantity : 5 L
ADR - Tunnel code :
E : Passage forbidden through tunnels of category E
14.2. Sea transport (IMDG) [English only]
Proper shipping name : TOXIC LIQUID, ORGANIC, N.O.S.
UN N° : 2810
IMO-IMDG - Class or division : 6.1 : Toxic substances.
IMO-IMDG - Packing group : III
IMO- IMDG - Packing instructions : P001 LP01
IMO-IMDG - Limited quantities : 5
L IMO-IMDG - Marine pollution : No
EMS-Nr : F-A S-A
14.3. Air transport (ICAO-IATA) [English only]
Proper shipping name : TOXIC LIQUID, ORGANIC, N.O.S.
UN N° : 2810
IATA - Class or division : 6.1 : Toxic substances.
IATA - Packing group : III
IATA - Passenger and Cargo Aircraft : ALLOWED
- Passenger and Cargo - Packing : 655
instruction
- Passenger and Cargo - Maximum : 60 L
Quantity/Packing
IATA - Cargo only : ALLOWED
- Cargo only - Packing instruction : 663
- Cargo only - Maximum Quantity/ : 220 L
Packing IATA - Limited Quantites : 2 L
ERG-Nr : 6L
15.1. Safety, health and environmental regulations/legislation specific for the
substance or mixture
Safety, health and environmental : Ensure all national/local regulations are observed.
regulations/legislation specific for the substance or mixture
REACH Restrictions - Annex XVII : The components of this product are not subject to
restrictions.
REACH Authorisation - Annex XIV : The components of this product are not subject
to authorization.
15.2. Chemical Safety Assessment
Chemical Safety Assessment : It has not been carried out.
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None
. In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
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