NN DIMETHYL FORMAMIDE 99% GC
- Part number
- RXSOL-60-6605-030
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
The primary use of DMF is as a solvent with low evaporation rate. ... It is a common solvent in the Heck reaction. It is also a common catalyst used in the synthesis of acyl halides, in particular the synthesis of acyl chlorides from carboxylic acids using oxalyl or thionyl chloride.
Applications
NN DIMETHYL FORMAMIDE 99% GC The pharmaceutical industry uses DMF as a reaction and crystallization solvent because of its exceptional solvency parameters. ... DMF is also used as carrier for inks and dyes in various printing and fiber-dying applications. DMF is widely used as a solvent, reagent and catalyst in the synthetic organic chemistry.
Dosage and directions
DMF is a common solvent for chemical reactions. Dimethylformamide is odorless, but technical-grade or degraded samples often have a fishy smell due to impurity of dimethylamine.
Characteristics and notes
N,N-Dimethylformamide is a colorless, odorless water-miscible liquid solvent used in the production of acrylic fibers, plastics, pesticides, and synthetic leather. It is also used in the manufacture of paint, film, and adhesives. Currently more than 100,000 workers per year are exposed to the solvent.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | NN DIMETHYL FORMAMIDE 99% GC |
| Part Number | RXSOL-60-6605-030 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA
| Phone | +91 22 20871200 - 1400 |
| Fax | +91 22 27612100 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
| Chemical Name | CAS | EC NO. | Weight |
| N,N-Dimethylformamide (DMF) GC-HS, 99.9% | 68-12-2 | 200-679-5 | 100 |
| Signal Word | NA |
| Risk advice to man and the environment |
Toxic if swallowed. Very toxic in contact with skin. Irritating to eyes, respiratory system and skin
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
|
| Precautionary statements - response | NA. |
| Response | NA. |
| Disposal | NA |
| Storage | NA |
| Prevention | NA |
| Supplemental Hazard Statements | NA |
| Other hazards | NA. |
| General advice | Consult a physician. Show this safety data sheet to the doctor in attendance. |
| Inhalation | If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician. |
| Eye Contact | Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician |
| swallowed | After swallowing: immediately make victim drink water (two glasses at most). Consult a physician. |
| Skin Contact | Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physiciane |
| Ingestion: | Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician |
| Notes to Physician | Treat symptomatically |
| If swallowed | After swallowing: immediately make victim drink water (two glasses at most). Consult a physician. |
| Most important symptoms and effects, both acute and delaye | No known significant effects or critical hazards. |
| Indication of any immediate medical attention and special treatment needed | No data available |
| Extinguishing media | NA |
| Flammability | NA |
| Flash Point | NA |
| Suitable extinguishing media | NA |
| Unsuitable extinguishing media | NA |
| Special hazards arising from the substance or mixture | NA |
| Personal precautions, protective equipment and emergency procedures |
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance
contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
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|
Environmental precautions
Environmental precautions |
Do not let product enter drains. Risk of explosion |
| Methods and materials for containment and cleaning up |
Prevent further leakage or spillage if safe to do so. Do not let product enter drains
let product enter drains.Prevent further leakage or spillage if safe to do so. Do not
let product enter drains.
|
|
Reference to other sections
Reference to other sections
No additional information available
|
No additional information available
No additional information available
|
| Advice on safe handling | Work under hood. Do not inhale substance/mixture. |
| Advice on protection against fire and explosion | Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge |
| Hygiene measures | Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. For precautions |
| Precautions fo safe handling | Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam. |
| Protective measures | Put on appropriate personal protective equipment (see Section 8). Avoid exposure - obtain special instructions before use. Avoid exposure during pregnancy. Do not handle until all safety precautions have been read and understood. Do not get in eyes or on skin or clothing. Do not ingest. Avoid breathing vapor or mist. If during normal use the material presents a respiratory hazard, use only with adequate ventilation or wear appropriate respirator. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container |
| Conditions for safe storage, including any incompatibilities | Store between the following temperatures: 15 to 30°C (59 to 86°F). Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Store locked up. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination |
| Storage conditions | Tightly closed. Keep away from heat and sources of ignition. Keep locked up or in an area accessible only to qualified or authorized persons. Light sensitive. Moisture sensitive. |
| Storage conditions | Tightly closed. Dry |
| Storage class | Storage class (TRGS 510): 13: Non Combustible Solids |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Handling |
Keep away from heat. Keep away from sources of ignition. Keep away from combustible material.. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as reducing agents, combustible materials, organic materials, metals |
| Advice on general occupational hygiene | Advice on safe handling Observe label precautions. Change contaminated clothing. Wash hands after working with substance. |
| Respiratory Protection | Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). |
| Hand Protection | The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Handle with gloves |
| Eye Protection | Safety glasses |
| Skin and body protection | Choose body protection according to the amount and concentration of the dangerous substance at the work |
| Hygiene measures | Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product |
| Thermal hazards | No data available |
Gloves Suit
| Physical state | Liquid |
| Colour | NA |
| Odour | NA |
| Molecular Weight | 73.10 |
| Odor Threshold | NA |
| pH | Not Applicable |
| Melting Point | -61°C |
| Boiling Point | 153°C |
| Flash Point | 58°C - closed cup |
| Evaporation Rate | NA |
| Explosive limits | No Data Available |
| Upper/lower flammability or explosive limits | No data available |
| Autoignition temperature | No data available |
| Decomposition temperature | No data available |
| Relative density | NA |
| Vapour pressure | NA |
| Density | No data available |
| Vapour Density | No Data Available |
| Specific Gravity | no data available |
| Partition coefficient | No data available |
| Explosive properties | None |
| Solubility | NA |
| Ignition temperature | No information available. |
| Particle characteristics | No data available |
| Viscosity | NA |
| Reactivity | Vapor/air-mixtures are explosive at intense warming. |
| Chemical stability | The product is chemically stable under standard ambient conditions (room temperature) |
| Possibility of hazardous reactions |
Alkali metals
Halogens
Halides
Reducing agents
Triethylaluminium
Nitrates
|
| Conditions to avoid | Heating. |
| Incompatible materials | various plastics, Copper, Copper alloys, Tin, Strong oxidizing agents |
| Hazardous Polymerization | NA |
| Hazardous decomposition products | ucts In the event of fire: see section 5 |
| Acute toxicity | LD50 Oral - Rat - male and female - 3.010 mg/kg (OECD Test Guideline 401) Acute toxicity estimate Inhalation - 4 h - 11,1 mg/l - vapor (Expert judgment) Remarks: (Regulation (EC) No 1272/2008, Annex VI) LD50 Dermal - Rabbit - 1.500 mg/kg Remarks: (Regulation (EC) No 1272/2008, Annex VI) (IUCLID) |
| Skin corrosion/irritation | Skin - Rabbit Result: No skin irritation - 20 h Remarks: (ECHA) |
| Serious eye damage/eye irritation | Eyes - Rabbit Result: Irritating to eyes. (OECD Test Guideline 405) Remarks: (Regulation (EC) No 1272/2008, Annex VI) |
| Respiratory or skin sensitization |
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 406
|
| Serious eye damage/eye irritation | No data available |
| Rout Of Entry | NA |
| Toxicity to Animal | NA. |
| Toxic Effects on Human | NA |
| Germ cell mutagenicity | Sister chromatid exchange assay Test system: Chinese hamster ovary cells Metabolic activation: with and without metabolic activation |
| Reproductive toxicity | No data available |
| Specific target organ toxicity - single exposure | No data available |
| Special Remarks on other Toxi Effects on Humans: |
NA |
| Additional Information | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. |
| Assessment | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: OD2800000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Other dangerous properties can not be excluded. Handle in accordance with good industrial hygiene and safety practice. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: DK2625000 burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, Damage to the eyes. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Stomach - Irregularities - Based on Human Evidenc |
|
Toxicity Persistence and degradability |
Conclusion/Summary There are no data available on the mixture itself. Conclusion/Summary There are no data available on the mixture itself. |
| Bioaccumulative potential | No data available |
| Toxicity to fish |
flow-through test LC50 - Lepomis macrochirus (Bluegill sunfish) -
7.100 mg/l - 96 h
(US-EPA)
|
| Toxicity to daphnia and other aquatic invertebrates | static test EC50 - Daphnia magna (Water flea) - 13.100 mg/l - 48 h (OECD Test Guideline 202) |
| Toxicity to algae | static test ErC50 - Desmodesmus subspicatus (green algae) - > 1.000 mg/l - 72 h (DIN 38412) |
| Eco Toxicity | Not Available |
| COD and BOD 5 | Not Available |
| Products Biodegradation: | The methods for determining the biological degradability are not applicable to inorganic substances. |
| Mobility in soil | No Information available |
| Results of PBT and vPvB assessment | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher |
| Assessment | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. |
| Other adverse effects | No data available |
| Bioaccumulative potential | Cyprinus carpio (Carp) - 56 d at 25 °C - 0,002 mg/l(N,N-dimethylformamide) Bioconcentration factor (BCF): 0,3 - 1,2 (OECD Test Guideline 305C) |
| Mobility in soil | No data available |
| Disposal methods | NA |
| Contaminated packaging | NA |
| Waste treatment Method |
See www.retrologistik.com for processes regarding the return of chemicals and
containers, or contact us there if you have further questions.
|
| UN number |
ADR/RID: 2265 IMDG: 2265 IATA: 2265 |
| UN proper shipping name |
ADR/RID: N,N-DIMETHYLFORMAMIDE
IMDG: N,N-DIMETHYLFORMAMIDE
IATA: N,N-Dimethylformamide
|
| Transport hazard class(es) |
ADR/RID: 3 IMDG: 3 IATA: 3 |
| Packaging group |
ADR/RID: III IMDG: III IATA: III |
| Environmental hazards |
ADR/RID: No IMDG: No IATA: No |
| Special precautions for user | Transport within user’s premises: always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage |
| Further information | Not classified as dangerous in the meaning of transport regulations. |
| Transport in bulk according to IMOinstruments | No data available |
| U.S. Federal regulations | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. |
| Safety, health and environmental regulations/legislation specific for the substance or mixture | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006 |
| Safety, health and environmental regulations specific for the product in question | European Inventory of Existing Commercial Chemical Substances (EINECS) -Listed.EC Inventory Listed. United States Toxic Substances Control Act (TSCA) Inventory- Listed. China Catalog of Hazardous chemicals 2015 Not- Listed. New Zealand Inventory of Chemicals (NZIoC)Listed. PICCS -Listed. Vietnam National Chemical Inventory -Listed. IECSC Listed. Korea Existing Chemicals List (KECL) -Listed. |
| National legislation |
Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of
major-accident hazards involving dangerous substances.FLAMMABLE LIQUIDS
|
| DSCL (EEC) | R8- Contact with combustible material may cause fire. R20/22- Harmful by inhalation and if swallowed. R36/37/38- Irritating to eyes, respiratory system and skin. R42/43- May cause sensitization by inhalation and skin contact. S22- Do not breathe dust. S24- Avoid contact with skin. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37- Wear suitable gloves. |
| Other regulations | Take note of Dir 94/33/EC on the protection of young people at work. |
| Chemical Safety Assessment | For this product a chemical safety assessment was not carried out. |
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
