O PHENYLENEDIAMINE FOR SYNTHESIS
- Part number
- RXSOL-60-6605-137
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
o-Phenylenediamine has been prepared by the reduction of o-nitroaniline by means of tin and hydrochloric acid,1 stannous chloride and hydrochloric acid,2 sodium stannite,3 zinc dust and water,4 sodium hydrosulfite and sodium hydroxide,5 and zinc dust and alcoholic alkali;6 by electrolytic reduction in aqueous alcohol.
Applications
o-Phenylenediamine mainly functions as a dye substance in oxidative hair dye products. The substance can be found in cosmetic products* such as hair dyes, hair colors, hair tints and rinses.
Characteristics and notes
The zinc dust should be at least 80 per cent pure, and the amount used should be equivalent to 130 g. of 100 per cent material. A large excess of zinc dust has been used without changing the yield.
Great care must be taken not to add too much zinc dust at first as the reaction becomes very vigorous. It is well to have a bath of ice and wet towels at hand in order to control the reaction if it should become too violent.
Occasionally the reaction suddenly stops and it is necessary to add an additional 10 cc. of 20 per cent sodium hydroxide solution, which causes the reaction to proceed.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | O PHENYLENEDIAMINE FOR SYNTHESIS |
| Part Number | RXSOL-19-1279-025 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA
| Phone | +91 22 20871200 - 1400 |
| Fax | +91 22 27612100 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com | |
| Website | www.rxmraine.com |
| Chemical Name | CAS | EC number | Weight | Formula |
| Cresyl diphenyl phosphate | 26444-49-5 | 247-693-8 | <= 100 % | CP |
| Signal Word | Danger |
| Hazard Statements | H302 Harmful if swallowed. H410 Very toxic to aquatic life with long lasting effects. |
| Precautionary statements |
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P302 + P352 + P312 IF ON SKIN: Wash with plenty of water.Call a POISON CENTER/ doctor if you feel unwell. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
|
| Classification of the substance or mixture | Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008. |
| Supplemental Hazard Statements | None. |
| Other hazards | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| General advice | Show this material safety data sheet to the doctor in attendance. |
| If inhaled | After inhalation: fresh air. |
| Eye Contact | After eye contact: rinse out with plenty of water. Remove contact lenses. |
| Swallowed | After swallowing: immediately make victim drink water (two glasses at most). Consult a physician. |
| Skin Contact | In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. |
| Inhalation | Remove patient to fresh air, keep warm and at rest and get medical assistance in necessary. |
| Ingestion | Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately. |
| Most important symptoms and effects, both acute and delaye | The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 |
| Indication of any immediate medical attention and special treatment needed | No data available |
| Flammability | May be combustible at high temperature. |
| Suitable extinguishing media | Water Foam Carbon dioxide (CO2) Dry powder |
| Unsuitable extinguishing media | For this substance/mixture no limitations of extinguishing agents are given. |
| Special hazards arising from the substance or mixture | Carbon oxides Nitrogen oxides (NOx) Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire. |
| Further information | The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 |
|
Hazardous combustion products |
Fire may cause the evolution of Sulphur oxides, nitrogen oxides. |
| Advice for firefighters | In the event of fire, wear self-contained breathing apparatus. |
| Protective Equipment | Use personal protective equipment. |
| Specific Hazards Arising from the Chemical |
Has a fire-promoting effect due to the release of oxygen. Ambient fire may liberate hazardous vapours. |
| Indication of any immediate medical attention and special treatment needed | No data available |
| Personal precautions, protective equipment and emergency procedures | Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8. |
| Spillage | Oxidizing material. Stop leak if without risk. Avoid contact with a combustible material (wood, paper, oil, clothing...). Keep substance damp using water spray. Do not touch spilled material. Prevent entry into sewers, basements or confined areas dike if needed. Eliminate all ignition sources. Call for assistance on disposal. |
| Personal Protection | Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: Protective equipment see section 8. |
| Enviromental Precaution | Do not let product enter drains. |
|
Methods and materials for containment and cleaning |
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ). Dispose of properly. Clean up affected area. |
| Advice on safe handling | Work under hood. Do not inhale substance/mixture. |
| Advice on protection against fire and explosion | Provide appropriate exhaust ventilation at places where dust is formed. |
| Incompatible materials | Keep away from alkalis, strong oxidizing agents and metals. Provide containment walls of adequate capacity to hold any accidental spills. |
| Hygiene measures | Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. For precautions see section 2.2. |
| Precautions for safe handling | For precautions see section 2.2. |
| Conditions for safe storage, including any incompatibilities | Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials. |
| Storage conditions | Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons. |
| Storage class | Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Advice on general occupational hygiene | Advice on safe handling Observe label precautions. Change contaminated clothing. Wash hands after working with substance. |
| Requirements for storage | Keep in cool and store under shade. |
| Exposure controls | No specific additional engineering controls are required. Provide good natural or artificial ventilation. |
| Engineering Control | Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. |
| Eye/face protection | Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses |
| Body Protection | Protective clothing |
| Skin protection | Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. |
| Respiratory protection | Recommended Filter type: Filter A-(P3) The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. |
| Other Protection Measure | Handle in accordance with good industrial hygiene and safety practice. |
| Control of environmental exposure | Do not let product enter drains. |
| Thermal hazards | No data available |
| Physical state | Solid |
| Colour | White, tan |
| Odour | No data available |
| Odor Threshold | Not Applicable |
| pH | 8,7 |
| Melting Point | 98 - 102 °C |
| Boiling Point | 256 - 258 °C |
| Flash Point | 136 °C - closed cup |
| Evaporation Rate | Not Applicable |
| Flammability (solid, gas) | No data available |
| Explosive limits | No Data Available |
| Upper flammability or explosive limits | 1,5 %(V) |
| Autoignition temperature | No data available |
| Decomposition temperature | No data available |
| Vapour pressure | 0,001 hPa at 20 °C |
| Density | 0,72 g/cm3 at 24 °C |
| Vapour Density | No data available |
| Freezing point | No data available |
| Specific Gravity | No data available |
| Partition coefficient | log Pow: 0,12 at 25 °C |
| Explosive properties | No data available |
| Solubility | 39,3 g/l at 20 °C |
| Ignition temperature | No information available. |
| Particle characteristics | No data available |
| Reactivity | Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed. |
| Stability | The product is chemically stable under standard ambient conditions (room temperature) . |
| Possibility of hazardous reactions | Violent reactions possible with: Strong oxidizing agents Strong acids Acid anhydrides acid halides |
| Conditions to avoid | Strong heating. |
| Incompatible materials | Strong oxidizing agents |
| Hazardous Polymerization | In the event of fire: see section 5 |
| Acute toxicity | Acute toxicity estimate Oral - 100,1 mg/kg (Expert judgment) Remarks: (Regulation (EC) No 1272/2008, Annex VI) LC50 Inhalation - Rat - male - 4 h - 3,6 mg/l - dust/mist Remarks: (Regulation (EC) No 1272/2008, Annex VI) Acute toxicity estimate Dermal - 1.100,1 mg/kg (Expert judgment) Remarks: (Regulation (EC) No 1272/2008, Annex VI) LDLo Dermal - Rabbit - 1.500 mg/kg Remarks: (RTECS) |
| Skin corrosion/irritation | Skin - Rabbit Result: No skin irritation - 4 h (OECD Test Guideline 404) |
| Serious eye damage/eye irritation | Eyes - Rabbit Result: Eye irritation - 72 h (OECD Test Guideline 405) |
| Respiratory or skin sensitization | Maximization Test - Guinea pig Result: May cause sensitization by skin contact. |
| Toxic Effects on Human | May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer). |
| Carcinogenicity | Limited evidence of carcinogenicity in animal studies |
| Germ cell mutagenicity | In vitro tests showed mutagenic effects Test Type: Ames test Test system: Salmonella typhimurium Metabolic activation: Metabolic activation Method: OECD Test Guideline 471 Result: positive Test Type: Micronucleus test Species: Guinea pig Application Route: Intraperitoneal Result: positive Remarks: (ECHA) |
| Reproductive toxicity | May damage the unborn child. May damage fertility. |
| Specific target organ toxicity - single exposure | Mixture may cause drowsiness or dizziness. |
| Special Remarks on other Toxi Effects on Humans | Acute Potential Health Effects: Skin: Causes skin irritation. May cause skin sensitization, an allergic reation, which becomes evident upon re-exposure to this material. Eyes: Causes eye irritation. Ingestion: Causes gastrointestinal (digestive) tract irritation with nausea, vomiting, and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May cause chemical pneumonitis and pulmonary edema, inflammation, edema of bronchi and larynx. Chronic Potential Health Effects: Repeated or prolonged skin exposure may cause allergic reactions in sensitive individuals. Repeated or prolonged exposure by inhalation may affect respiration and metabolism. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Repeated dose toxicity - Rat - male - Oral - NOAEL (No observed adverse effect level) - 400 mg/kg Exposure can cause numbness, tingling, and weakness in extremities., Nausea, Dizziness, Headache, Central nervous system depression, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. |
| Persistence and degradability | Biodegradability aerobic - Exposure time 28 d Result: 0 % - Not biodegradable (OECD Test Guideline 301C) |
| Toxicity to fish | Flow-through test LC50 - Oncorhynchus mykiss (rainbow trout) - 42,9 mg/l - 96 h Remarks: (ECHA) |
| Toxicity to daphnia and other aquatic invertebrates | Semi-static test NOEC - Daphnia magna (Water flea) - 0,065 mg/l - 21 d |
| Toxicity to algae | Static test EC50 - Pseudokirchneriella subcapitata - 0,16 mg/l - 96 h Remarks: (ECHA) |
| Toxicity to bacteria | EC50 - Bacteria - 580 mg/l - 3 h (OECD Test Guideline 209) |
| Mobility in soil | No Information available |
| Results of PBT and vPvB assessment | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. |
| Other adverse effects | Discharge into the environment must be avoided. Further information on ecology Forms toxic mixtures in water, dilution measures notwithstanding. Biological effects |
| Disposal methods | The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems. |
| Waste treatment Method | No data available . |
| UN number | ADR/RID:1673 IMDG:1673 IATA:1673 |
| UN proper shipping name |
ADR/RID:Phenylenediamines IMDG: Phenylenediamines IATA:Phenylenediamines |
| Transport hazard class(es) | ADR/RID: 6.1 IMDG: 6.1 IATA:6.1 |
| Packaging group | ADR/RID: III IMDG: III IATA:III |
| Environmental hazards | ADR/RID: No IMDG: No IATA: No |
| Special precautions for user | Tunnel restriction code : (C/E) |
| Further information | Not classified as dangerous in the meaning of transport regulations. |
| Inventory status | Components are on the following inventories: Polymaleic acid: - US TSCA, Canadian DSL, EU EINECS, Australian AICS, Korean, Philippine PICCS and Chinese Xi irritant R 36/38 Irritant to eyes & skin R 41 Risk of serious damage to eyes S24/25 Avoid contact with skin and eyes S26/28 In case of contact eyes & skin, rinse with plenty water and seek medical advice Section 312/313: Not listed. Not listed under California proposition 65. |
| Safety, health and environmental regulations/legislation specific for the substance or mixture | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. |
| National legislation | Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. : ENVIRONMENTAL HAZARDS |
| Other regulations | Observe work restrictions regarding maternity protection in accordance to Dir 92/85/EEC or stricter national regulations where applicable. Take note of Dir 94/33/EC on the protection of young people at work. |
| Chemical Safety Assessment | For this product a chemical safety assessment was not carried out . |
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
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