PHLOXIN B FOR MICROSCOPY
- Part number
- RXSOL-60-6605-229
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
The CERTISTAIN dry dye Phloxin B (C.I. 45410) is used for the preparation of a staining solution for cytoplasmic staining in histological sections of human origin. It is mainly used in Hemytoxylin and Eosin (H&E) overview staining that is routinely performed in histological laboratories.
Applications
Phloxine B can be used as a differential versatile bacterial stain and establishes a correlation between the staining properties of the dye and its bactericidal effect.
Dosage and directions
Phloxine B can be used to stain deads cell of several yeasts, including Saccharomyces cerevisiae and Schizosaccharomyces pombe. When diluted in yeast growth media, the dye is unable to entere cell because of their membranes.
Characteristics and notes
Phloxine B (commonly known simply as phloxine) is a water-soluble red dye used for coloring drugs and cosmetics in the United States[2] and coloring food in Japan.[3] It is derived from fluorescein, but differs by the presence of four bromine atoms at positions 2, 4, 5 and 7 of the xanthene ring and four chlorine atoms in the carboxyphenyl ring.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | PHLOXIN B FOR MICROSCOPY |
| Part Number | RXSOL-60-6605-229 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai, Chennai, Vizag , Kolkata, UAE, OMAN and KENYA
| Phone | +91 22 2087 1200 - 1400 |
| Fax | +91 22 2087 1500 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com | |
| Website | www.rxmarine.com |
| Chemical Name | CAS number | EC-No. | Weight % |
| PHENYL TRIMETHYL AMMONIUM CHLORIDE | 18472-87-2 | 242-355-6 | 98% |
| Classification of the substance or mixture | Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008 |
| Label elements | Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008. |
| Other hazards | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Description of first-aid measures If inhaled | After inhalation: fresh air.. |
| After inhalation: fresh air. | In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower |
| In case of eye contact | After eye contact: rinse out with plenty of water. Remove contact lenses. |
| If swallowed | After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell. |
| Most important symptoms and effects, both acute and delayed | The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 |
| Indication of any immediate medical attention and special treatment needed | No data available |
| Extinguishing media Suitable extinguishing media | Water Foam Carbon dioxide (CO2) Dry powder |
| Unsuitable extinguishing media | For this substance/mixture no limitations of extinguishing agents are given. |
| Special hazards arising from the substance or mixture | Carbon oxides Nitrogen oxides (NOx) Hydrogen chloride gas Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire |
| Advice for firefighters | In the event of fire, wear self-contained breathing apparatus. |
| Further information | Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system |
| Personal precautions, protective equipment and emergency procedures |
Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. For personal protection see section 8.
|
| Environmental precautions |
Do not let product enter drains.
|
| Methods and materials for containment and cleaning up |
LCover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts
|
| Reference to other sections | For disposal see section 13. |
| Precautions for safe handling |
For precautions see section 2.2.
|
| Storage conditions | Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons. |
| Storage class | Storage class (TRGS 510): 6.1C: Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Eye/face protection |
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
|
| Skin protection |
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de). Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:KCL 741 Dermatril® L
|
| Body Protection |
Protective clothing
|
| Respiratory protection |
Required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P3 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
|
| Control of environmental exposure | Do not let product enter drains. |
Gloves Suit
| Appearance | Solid |
| Color | Dark brown |
| Odor | No data available |
| Melting point/freezing point | No data available |
| Initial boiling point and boiling range | No data available |
| Flammability (solid, gas) | No data available |
| Upper/lower flammability or explosive limits | No data available |
| Flash Point | No data available |
| Autoignition temperature | No data available |
| PH | No data available |
| Viscosity | No data available |
| Water solubility | No data available |
| Partition coefficient: n-octanol/water | No data available |
| Vapour pressure | No data available |
| Bulk Density | Ca.650 kg/m3 |
| Reactivity | Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed. |
| Chemical stability | The product is chemically stable under standard ambient conditions (room temperature) |
| Possibility of hazardous reactions | Violent reactions possible with: strong alkalis |
| Conditions to avoid | Strong heating. |
| Incompatible materials | Strong oxidizing agents |
| Hazardous decomposition products | In the event of fire: see section 5 |
| Acute toxicity | LD50 Oral - Rat - 8.400 mg/kg Inhalation: No data available Dermal: No data available) |
| Skin corrosion/irritation | No data available |
| Serious eye damage/eye irritation | No data available |
| Respiratory or skin sensitization | No data available |
| Germ cell mutagenicit | Test Type: Human Test system: Lungs Remarks: Mutation in mammalian somatic cells. |
| Sensitisation | No end point data for material. |
| Skin Sensitization | Data available. |
| Aspiration | Data available. |
| Germ Cell Mutagenicity | Data available. |
| Carcinogenicity | Data available. |
| Lactation | No end point data for material. |
| Single Exposure | NA |
| Assessment | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. |
| Additional Information | To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. |
| Toxicity to fish | Toxicity to fish LC50 - Gambusia affinis (Mosquito fish) - 97,7 mg/l - 96 h |
| Toxicity to daphnia and other aquatic invertebrates |
No data available
|
| Toxicity to alga | No data available |
| Persistence and degradability | No data available |
| Results of PBT and vPvB assessmen | His substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Other adverse effects |
No data available
|
| Waste treatment method | Waste must be disposed of in accordance with federal, state and local environmental control regulations |
| UN number | ADR/RID: IMDG: IATA: |
| UN proper shipping name |
ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods |
| Transport hazard class(es) |
ADR/RID: IMDG: IATA: |
| Packaging group |
ADR/RID: MDG: IATA: |
| Environmental hazards |
ADR/RID: No IMDG Marine pollutant: No IATA: No |
| Safety, health and environmental regulations/legislation specific for the substance or mixture | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006 |
| Other regulations | The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the Millipore- 1.15926 Page 8 of 8 The life science business of Merck operates as MilliporeSigma in the US and Canada present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Sigma-Aldrich Corporation and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See www.sigma-aldrich.com and/or the reverse side of invoice or packing slip for additional terms and conditions of sale. |
| Chemical Safety Assessment |
For this product a chemical safety assessment was not carried out
|
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
