SPAN 40 Sorbitan Monopalmitate
- Part number
- RXSOL-60-6605-597
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Sorbitan monopalmitate (SMP) is a food additive, permitted by the EU. It is entry E495 in the E number list of permitted food additives. It is also known under the trade name Span 40.
Applications
Span 40 is used in skin care, hair care and decorative cosmetics. It is also used as an effector in compositions capable of facilitating penetration across a biological barrier. Inactive ingredient of some medications it improves transdermal delivery of drugs and is a potential carrier for topical drug delivery.
Characteristics and notes
The Panel noted that after oral administration sorbitan monostearate can be either hydrolysed to its fatty acid moiety and the corresponding anhydrides of sorbitol and excreted via urine or exhaled as CO2 or excreted intact in the faeces. The Panel considered that sorbitan esters did not raise concern for genotoxicity. Based on the no observed adverse effect level (NOAEL) of 2,600 mg sorbitan monostearate/kg bw per day, taking into account the ratio between the molecular weight of sorbitan monostearate (430.62 g/mol) and sorbitan (164.16 g/mol), and applying an uncertainty factor of 100, the Panel derived a group ADI of 10 mg/kg bw per day expressed as sorbitan for sorbitan esters (E 491–495) singly or in combination.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | RXSOL-60-6605-597 |
| Product Type | SPAN 40 (Sorbitan Monopalmitate) |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation: +SPAN 40 (Sorbitan Monopalmitate)
CAS No :26266-57-9
Substance.
Contains no other components or impurities which will influence the classification of theproduct.
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Classification : Xi; R36/37/38
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008
(CLP) Health hazards : Specific Target Organ
Toxicity irritationCategory 3-- Single exposure Warning (CLP : STOT SE 3) H335
Skin irritationCategory 2 Acute toxicity, Oral-- Warning (CLP : Skin Corr. 2) H315
Category 4-- Respiratory tract Warning (CLP : Acute Tox. 4) H302
Eye irritationCategory 2AWarning (CLP
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Symbol(s) : Xi : Irritant
R Phrase(s) : Eye Irrit. 2)
H319 : R36/37/38 : Irritating to eyes, respiratory system and skin.
S Phrase(s) and seek : S26 : In case of contact with eyes, rinse immediately with ple medical advice.
S36 : Wear suitable protective clothing.
Labelling Regulation EC 1272/2008 (CLP)
Hazard pictograms
Signal words: Warning
Hazard statements: H302 : Harmful if swallowed.
H319 : Causes serious eye irritation.
H315: Causes skin irritation.
H335 : May cause respiratory irritation.Precautionary statements
• Prevention: P280: Wear protective gloves, protective clothing, eye protection, faceprotection.
P271: Use only outdoors or in a well-ventilated area.
P261: Avoidbreathing dust, fume, gas, mist, vapours, spray.
P264: Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
• Response: P302+P352: IF ON SKIN : Wash with plenty of soap and water.
P301+P312: IF SWALLOWED : Call a POISON CENTER or doctor if you feelunwell.
P332+P313: If skin irritation occurs : Get medical advice.
P305+P351+P338: IF IN EYES : Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340:IF INHALED : Remove to fresh air and keep at rest in a positioncomfortable for breathing.
P363: Wash contaminated clothing before reuse.
• Storage: P403+P233: Store in well-ventilated place. Keep container tightly closed.P405: Store locked up.
• Disposal considerations: P501: Dispose of this material and its container to hazardousor special
wastecollection point, in accordance with local, regional, national and/orinternationalregulation.
3.3. Other hazards
Other hazards: The substance does not fulfil the criteria to be identified as PBT
substance or vPvBsubstance according to Annex XIII of Regulation REACH
4.1. Description of first aid measures
Inhalation: Call a POISON CENTER or doctor if you feel unwell.
Remove to fresh airand keepat rest in aposition comfortable for breathing.
Skin contact: Specific treatment (see on this label). Get medical advice.
If skin irritationoccurs :Wash with plenty of soap and water. Wash contaminated clothing before reuse.
Eye contact: Remove contact lenses, ifpresent and easy to do. Continue rinsing.
Rinsecautiously with water for several minutes.
If eye irritation persists : Get medicaladvice.Ingestion: Obtain emergency medical attention.
Do NOT induce vomiting. Rinse mouth.Call aPOISON CENTER or doctorif you feel unwell.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use: Swallowing a small quantity of this material will result inserious health hazard.
Causes serious eye irritation.Causes skin irritation. May causerespiratory irritation.
4.3. Indication of any immediate medical attention and special treatment needed
General information: Never give anything by mouth to an unconscious person.
If youfeel unwell, seekmedical advice (show the label where possible).
5.1. Extinguishing media
Suitable extinguishing media: Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media: Do not use a heavy water stream.
Surrounding fires: Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products: Under fire conditions, hazardous fumes will bepresent.
5.3. Advice for fire-fighters
Protection against fire: Do not enter fire area withoutproper protective equipment,including
respiratoryprotection.Special procedures: Exercise caution when fighting any chemical fire.
Avoid (reject)fire-fighting water toenter environment.
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders: Equip cleanup crew with proper protection.Ventilate area.
For non-emergency personnel: Evacuate unnecessary personnel.
6.2. Environmental precautions
Environmental precautions: Prevententry to sewers and public waters.
Notifyauthorities if product enterssewers or public waters.
6.3. Methods and material for containment and cleaning up
Clean up methods: On land, sweep or shovel into suitable containers
Minimizegeneration of dust.Store away from other materials.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling: Wash thoroughly after handling. Do not eat, drink or smoke when using thisproduct.
Use only outdoors or in a well-ventilated area. Wash thoroughly afterhandling.
Technical protective measures: Provide good ventilation in process area to preventformation of vapour.
Special precautions: Avoid breathing dust, fume, gas,mist, vapours, spray.
7.2. Conditions for safe storage, including any incompatibilities
Storage: Keep only in the original container in a cool, well ventilated place.
Keepcontainertightly closed.
Storage-away from: Strong bases. Strong acids. Sourcesof ignition. Direct sunlight.
7.3. Specific end use
(s)Specific end use(s): None.
8.1. Exposure controls
Personal protection: Avoid all unnecessary exposure.
• Respiratory protection: Wear approved mask.
• Handprotection: Wear protective gloves
.• Skin protection: Wear suitable protective clothing.
• Eye protection: Chemical goggles or safety glasses.
• Others: When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits: Nodata available.
9.1. Information on basic physical and chemical properties
Physical state at 20 °C: Solid.
Odour threshold: No data available.
pH value: Not applicable.
Melting point [°C]: 46-47 °C
Decompositionpoint [°C]: N/A
Critical temperature [°C]: N/A
Auto-ignition temperature [°C]: N/A
Flammability (solid, gas): N/A
Flash point [°C]: 113 °C
Boiling point [°C]: N/A
Initial boiling point [°C]: N/A
Final boiling point [°C]: N/A
Evaporation rate: N/A
Vapour pressure [20°C]: N/A
Vapour pressure mm/Hg: N/A
Vapour density: N/A
Density [g/cm3]: N/A
Relative density, gas (air=1): N/A
Availability
SPAN 40 Sorbitan Monopalmitate manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
SPAN 40 Sorbitan Monopalmitate is available in small packing as well as in bulk. Buy premium quality SPAN 40 Sorbitan Monopalmitate and other lab chemicals from one of the most trusted brands.
