THIAZINE RED
- Part number
- RXSOL-60-6605-707
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Thiazine red staining is a reliable and rapid pos-mortem diagnostic tool for Alzheimer´s disease.Derivatives of thiazine, often referred to as thiazines, are used for dyes, tranquilizers and insecticides.
Applications
Thiazin Red is used as a counter-staining solution in Kit Fluo-Color for the detection of mycobacteria, also called AFB (Acid-Alcohol-Fast Bacilli), through the fluorescence staining technique according to Degommier.
Characteristics and notes
Strong evidence shows an association between cerebral vascular diseases and Alzheimer´s disease (AD). In order to study the interaction of beta-amyloid (Aβ) plaques with brain vessels, we crossbred an AD mouse model (overexpressing amyloid precursor protein with the Swedish-Dutch-Iowa mutations, APP_SweDI) with mice expressing green fluorescent protein (GFP) under the flt-1/VEGFR1 promoter in vessels (GFP_FLT1). Our data show, that only very few Aβ plaques were seen in 4-months old mice, focused in the mammillary body and in the lateral septal nucleus.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | THIAZINE RED |
| Part Number | RXSOL-60-6605-707 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA
| Phone | +91 22 20871200 - 1400 |
| Fax | +91 22 27612100 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com | |
| Website | www.rxmraine.com |
| Chemical Name | CAS | EC number | Weight | Formula |
| Sodium tungstate dihydrate | 2150-33-6 | 218-422-0 | <= 100 % | Na2O4W · 2H2O |
| Classification according to Regulation (EC) No 1272/2008 [CLP] |
Acute Tox. 4 ; H302 - Acute toxicity (oral) : Category 4 ; Harmful if swallowed.
Eye Dam. 1 ; H318 - Serious eye damage/eye irritation : Category 1 ; Causes serious eye damage.
|
| Labelling according to Regulation (EC) No. 1272/2008 [CLP] |
.Hazard pictograms
Corrosion (GHS05) · Exclamation mark (GHS07)
Signal word
DANGER
|
| Hazard statements | H318 Causes serious eye damage. |
| Trade name : | 112580 - Thiazine red (C.I. 14780) |
| Revision date : | 04/11/2022 |
| Print date : | 28/11/2022 |
| Version (Revision) : | 2.0.0 (1.0.0) |
| H302 | Harmful if swallowed. |
| P264 | Wash thoroughly after handling. |
| P270 | Do not eat, drink or smoke when using this product |
| P280 | Wear protective gloves/protective clothing/eye protection/face protection. |
| P310 | Immediately call a POISON CENTER/doctor. |
| P330 | Rinse mouth. |
| P305+P351+P338 |
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present
and easy to do. Continue rinsing.
|
| Other hazards | None |
| Description of first aid measures |
Remove contaminated, saturated clothing immediately. After contact with skin, wash immediately with plenty of water
and soap. In case of skin reactions, consult a physician. After contact with the eyes, rinse with water with the eyelids
open for a sufficient length of time, then consult an ophthalmologist immediately. If accidentally ingested, seek
immediate medical attention, NEVER induce vomiting. Remove victim out of the danger area. When in doubt or if
symptoms are observed, get medical advice
|
| Most important symptoms and effects, both acute and delayed |
Contact with eyes or skin can cause burns; ingestion or inhalation can cause internal damage, if this occurs immediate
medical assistance is required. Never give anything by mouth to an unconscious person or a person with cramps.
|
| Indication of any immediate medical attention and special treatment needed |
Request immediate medical attention. Never administer anything orally to persons who are unconscious. Do not induce
vomiting. If the person vomits, clear the respiratory tract. Cover the affected area with a dry sterile bandage. Protect
the affected area from pressure or friction
|
| Suitable extinguishing media | Extinguisher powder or CO2. In case of more serious fires, also alcohol-resistant foam and water spray |
| Unsuitable extinguishing media | Do not use a direct stream of water to extinguish. In the presence of electrical voltage, you cannot use water or foam |
| Trade name : | 112580 - Thiazine red (C.I. 14780) |
| Revision date : | 04/11/2022 |
| Print date : |
28/11/2022
|
| Version (Revision) : | 2.0.0 (1.0.0) |
| Special hazards arising from the substance or mixture |
Special risks: Fire can cause thick, black smoke. As a result of thermal decomposition, dangerous products can form:
carbon monoxide, carbon dioxide. Exposure to combustion or decomposition products can be harmful to your health
|
| Advice for firefighters |
IUse water to cool tanks, cisterns, or containers close to the heat source or fire. Take wind direction into account.
Prevent the products used to fight the fire from going into drains, sewers, or waterways. Wear a self-contained
breathing apparatus and chemical protective clothing. Do not inhale explosion and combustion gases.
|
| Additional information |
.Fire protection equipment: According to the size of the fire, it may be necessary to use protective suits against the heat,
individual breathing equipment, gloves, protective goggles or facemasks, and boots.
|
| Personal precautions, protective equipment and emergency procedures | Clear spills immediately |
| For non-emergency personnel | Wear a self-contained breathing apparatus and chemical protective clothing. Remove persons to safety. |
| For emergency responders |
Eliminate possible ignition points and ventilate the area. No smoking. Avoid breathing fumes.For exposure control and
individual protection measures, see section 8.
|
| Enviromental Precaution |
Do not allow to enter into surface water or drains. In case of gas escape or of entry into waterways, soil or drains,
inform the responsible authorities. Retain contaminated washing water and dispose it.
|
|
Methods and materials for containment and cleaning |
Collect in closed and suitable containers for disposal. |
| For cleaning up |
The contaminated area should be cleaned up immediately with: Water Soak up inert absorbent and dispose as waste
requiring special attention. Absorb with liquid-binding material (sand, diatomaceous earth, acid- or universal binding
agents). Avoid dust formation.
|
| Reference to other sections | Reference to other sections Disposal: see section 13 Personal protection equipment: see section 8 |
| Precautions for safe handling |
.When using do not eat, drink, smoke, sniff. Wear personal protection equipment
(refer to section 8).
|
| Trade name : | 112580 - Thiazine red (C.I. 14780) |
| Revision date : | 04/11/2022 |
| Print date : | 28/11/2022 |
| Version (Revision) : | 2.0.0 (1.0.0) |
| Environmental precautions | Use appropriate container to avoid environmental contamination |
| Specific requirements or handling rules | Handle and open container with care |
| Advices on general occupational hygiene | Take care for general good hygiene and housekeeping |
|
Technical measures and storage conditions
Storage temperature :
|
Keep in a cool, well-ventilated place. Protect against UV-radiation/sunlight Humidity. |
| Requirements for storage rooms and vessels | Only use containers specifically approved for the substance/product. |
| Hints on joint storage | Store at least 3 metres apart from: Chemicals/products that react together readily |
| Specific end use(s) | 13 |
| Control parameters |
The product does NOT contain substances with Professional Exposure Environmental Limit Values.The product does
NOT contain substances with Biological Limit Values.
|
| Exposure controls | Only wear fitting, comfortable and clean protective clothing. |
| Eye/face protection | Eye glasses with side protection Face protection shield EN 166 |
| Hand protection |
Tested protective gloves must be worn EN ISO 374 The quality of the protective gloves resistant to
chemicals must be chosen as a function of the specific working place concentration and quantity of hazardous
substances.
|
| Body Protection | For the protection against direct skin contact, body protective clothing is essential (in addition to the usual working |
| Trade name : | 112580 - Thiazine red (C.I. 14780) |
| Revision date : | 04/11/2022 |
| Print date | 28/11/2022 |
| Version (Revision) : | 2.0.0 (1.0.0) |
| Respiratory protection |
If technical exhaust or ventilation measures are not possible or insufficient, respiratory protection must be worn.
Particle filter device (EN 143).
|
| Thermal hazards | No information available. |
| Environmental exposure controls | No information available. |
| Appearance : | Solid |
| Melting point/freezing point : | ( 1013 hPa ) No data available |
|
Initial boiling point and boiling
range :
|
( 1013 hPa ) No data available |
| Decomposition temperature | ( 1013 hPa ) No data available |
| Flash point : | No data available |
| Auto-ignition temperature : | No data available |
| Lower explosion limit : | No data available |
| Upper explosion limit : | No data available |
| Vapour pressure : | ( 50 °C ) Not Applicable |
| Solvent separation test : | ( 20 °C not applicable |
| Water solubility : | ( 20 °C ) No Data Available |
| Fat solubility : | ( 20 °C ) No data available |
| pH : | No data available |
| log P O/W : | No data available |
| Flow time : | ( 20 °C ) No data available |
| Viscosity : | ( 20 °C )No data available |
| Relative vapour density : | 3,23 g/cm3 at 20 °C |
| Evaporation rate : | No data available |
| Flammable solids : | No data available |
| Flammable gases : | No data available |
| Explosive properties | No data available |
| Other information | None |
| Trade name : | 112580 - Thiazine red (C.I. 14780) |
| Revision date : | 04/11/2022 |
| Print date : | 28/11/2022 |
| Version (Revision) : | 2.0.0 (1.0.0) |
| Reactivity | The product does not present hazards by their reactivity. |
| Chemical stability |
The product is chemically stable under recommended conditions of storage, use and temperature. Safe handling: see
section 7
|
| Possibility of hazardous reactions | No hazardous reaction when handled and stored according to provisions. |
| Conditions to avoid | Avoid any improper handling. |
| Incompatible materials |
Keep away from oxidising agents and from highly alkaline or acidic materials in order to prevent exothermic reactions.
|
| Hazardous decomposition products | Depending on conditions of use, can be generated the following products: Corrosive vapors or gases. |
| Acute toxicity | No information available. |
| Skin corrosion/irritation | No information available |
| Serious eye damage/eye irritation | No information available. |
| Respiratory or skin sensitization | No information available |
| Carcinogenicity | No information available. |
| Germ cell mutagenicity | No information available. |
| Reproductive toxicity | No information available |
| STOT-single exposure | No information available |
| STOT-repeated exposure | No information available |
| Aspiration hazard | No information available. |
| Information on other hazards | No information available. |
| Trade name : | 112580 - Thiazine red (C.I. 14780) |
| Revision date : | 04/11/2022 |
| Print date : | 28/11/2022 |
| Version (Revision) : | 2.0.0 (1.0.0) |
| Toxicity | No information available |
| Persistence and degradability | No information available. |
| Bioaccumulative potential | No information available. |
| Mobility in soil | No Information available |
| Results of PBT and vPvB assessment | This substance does not meet the PBT/vPvB criteria of REACH, Annex XIII. |
| Endocrine disrupting properties |
No information available.
|
| Other adverse effects | No information available. |
| Waste treatment methods |
The allocation of waste identity numbers/waste descriptions must be carried out according to the EEC, specific to the
industry and process. Do not dump into sewers or waterways. Waste and empty containers must be handled and
eliminated according to current, local/national legislation. Follow the provisions of Directive 2008/98/EC regarding waste
management. Follow the provisions of Directive 2008/98/EC regarding waste management.
|
| Waste treatment options | Recycle according to official regulations. Evidence for disposal must be provided. |
| Appropriate disposal / Product | Dispose of waste according to applicable legislation. |
| Appropriate disposal / Package |
Non-contaminated packages must be recycled or disposed of. Contaminated packages must be completely emptied
and can be re-used following proper cleaning. Packing which cannot be properly cleaned must be disposed of.
Handle contaminated packages in the same way as the substance itself.
|
| UN number | No dangerous good in sense of these transport regulations. |
| UN proper shipping name | No dangerous good in sense of these transport regulations. |
| Transport hazard class(es) | No dangerous good in sense of these transport regulations. |
| Packaging group | No dangerous good in sense of these transport regulations. |
| Environmental hazards | No dangerous good in sense of these transport regulations. |
| Special precautions for user | None |
| Transport in bulk according to IMOinstruments |
No information available.
|
| Safety, health and environmental regulations/legislation specific for the substance or mixture |
Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH) Classification according to Regulation (EC) No
1272/2008 [CLP] according to Regulation (EU) No. 2020/878
|
| Regulation (EC) No. 1907/2006 (REACH), Annex XVII (restrictions) | Use restriction according to REACH annex XVII, no. : 3 |
| National regulations | |
| Water hazard class | Class : nwg (Non-hazardous to water) |
| Chemical Safety Assessment | No information available. |
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
Availability
[THIAZINE RED] manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
Lab chemicals manufacturers, suppliers, exporters in India, UAE Middle East, Barka, Sohar, Muscat, Oman, Canada.
[THIAZINE RED] is available in small packing as well as in bulk. Buy premium quality [THIAZINE RED] and other lab chemicals from one of the most trusted brands.
