THIOACETAMIDE AR
- Part number
- RXSOL-60-6605-708
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Thioacetamide has been used as an organic solvent in the leather, textile, and paper industries; as an accelerator in the vulcanization of buna rubber; and as a stabilizer of motor fuel.
Applications
Nanomedicine contributes to the efficiency of pharmacological treatments and progresses rapidly. The present study was designed to produce exopolysaccharide (BSEPS) from Bacillus subtilis sp. strain reported in our previous study was further characterized, and its BSEPS for synthesis of the nanoparticle Ag-BSEPS using microwave heating to determine the possible effects of a prepared solution containing Ag-BSEPS versus thioacetamide (TAA) evoked liver fibrosis in Wister albino rats. Nanoparticles with silver (Ag) core have been synthesized in an aqueous solution after exposure of BSEPS to periodate oxidation.
Dosage and directions
thioacetamide-induced apoptosis over an early time course of 0 to 8 h after administration.
Characteristics and notes
Environmental chemicals exposure is one of the primary factors for liver toxicity and hepatocarcinoma. Thioacetamide (TAA) is a well-known hepatotoxicant and could be a liver carcinogen in humans. The discovery of early and sensitive microRNA (miRNA) biomarkers in liver injury and tumor progression could improve cancer diagnosis, prognosis, and management.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | RXSOL-60-6605-708 |
| Product Type | THIOACETAMIDE AR |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
Substance / Preparation : Thioacetamide
CAS No :62-55-5
Substance.
Substance name Contents CAS No
Thioacetamide : 100 % 62-55-5
Contains no other components or impurities which will influence the classification of the product.
3.1. Classification of the substance or mixture
Classification EC 67/548 or EC 1999/45
Classification : Carc. Cat. 2; R45
Xn; R22
Xi; R36/38 R52-53
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Health hazards : Carcinogenicity - Category 1B - Danger (CLP : Carc. 1B) H350
Skin irritation - Category 2 - Warning (CLP : Skin Corr. 2) H315
Eye irritation - Category 2A - Warning (CLP : Eye Irrit. 2) H319
Acute toxicity, Oral - Category 4 - Warning (CLP : Acute Tox. 4) H302
Environmental hazards : Hazardous to the aquatic
environment - Chronic hazard - Category 3 (CLP : Aquatic Chronic 3) H412
3.2. Label elements
Labelling EC 67/548 or EC 1999/45
Symbol(s) : T : Toxic
R Phrase(s) : R45 : May cause cancer.
R22 : Harmful if swallowed.
R36/38 : Irritating to eyes and skin.
R52/53 : Harmful to aquatic organisms, may cause long-term adverse effects
in the aquatic environment.
S Phrase(s) : S53 : Avoid exposure - obtain special instructions before use.
S45 : In case of accident or if you feel unwell, seek medical advice immediately ( show the label when possible).
S61 : Avoid release to the environment. Refer to special instructions/Safety data sheets. Contains : Thioacetamide
Labelling Regulation EC 1272/2008 (CLP)
Hazard pictograms
Signal words : Danger
Hazard statements : H350 : May cause cancer.
H302 : Harmful if swallowed.
H319 : Causes serious eye irritation.
H315 : Causes skin irritation.
H412 : Harmful to aquatic life with long lasting effects.
Precautionary statements
• General : P201: Obtain special instructions before use.
• Prevention : P280: Wear protective gloves, protective clothing, eye protection, face protection.
P273: Avoid release to the environment.
P264: Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
• Response : P302+P352: IF ON SKIN : Wash with plenty of soap and water.
P301+P312: IF SWALLOWED : Call a POISON CENTER or doctor if you feel unwell.
P308+P313: If exposed or concerned : get medical advice.
P332+P313: If skin irritation occurs : Get medical advice.
P305+P351+P338: IF IN EYES : Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing.
P363: Wash contaminated clothing before reuse.
• Storage : P405: Store locked up.
• Disposal considerations : P501: Dispose of this material and its container to hazardous or
special waste collection point, in accordance with local, regional, national and/or international regulation.
Special labelling : Restricted to professional users. (Substances which appear in Part 3 of Annex VI to Regulation
(EC) No 1272/2008)
3.3. Other hazards
Other hazards : The substance does not fulfil the criteria to be identified as PBT
substance or vPvB substance according to Annex XIII of Regulation REACH.
4.1. Description of first aid measures
Inhalation : Assure fresh air breathing. Allow the victim to rest.
Skin contact : Specific treatment (see on this label). Wash contaminated clothing before reuse.
Get medical advice. Wash with plenty of soap and water.
If skin irritation occurs : Eye contact : Get medical advice. If eye irritation persists : Rinse
cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing. Ingestion : Obtain emergency medical attention. Do NOT induce vomiting.
Rinse mouth. Call a POISON CENTER or doctor if you feel unwell.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms relating to use : May cause cancer. Swallowing a small quantity
of this material will result in serious health hazard. Causes serious eye irritation. Causes skin irritation.
4.3. Indication of any immediate medical attention and special treatment needed
General information : Never give anything by mouth to an unconscious person.
If you feel unwell, seek medical advice (show the label where possible).
5.1. Extinguishing media
Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.
Unsuitable extinguishing media : Do not use a heavy water stream.
Surrounding fires : Use water spray or fog for cooling exposed containers.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion products : Under fire conditions, hazardous fumes will be present.
5.3. Advice for fire-fighters
Protection against fire : Do not enter fire area without proper protective equipment,
including respiratory protection.
Special procedures : Exercise caution when fighting any chemical fire
. Avoid (reject) fire-fighting water to enter environment.
6.1. Personal precautions, protective equipment and emergency procedures
For emergency responders : Equip cleanup crew with proper protection. Ventilate area.
For non-emergency personnel : Evacuate unnecessary personnel.
6.2. Environmental precautions Environmental precautions : Prevent entry to sewers and public waters.
Notify authorities if product enters sewers or public waters. Avoid release to the environment.
6.3. Methods and material for containment and cleaning up
Clean up methods : Soak up spills with inert solids, such as clay or diatomaceous
earth as soon as possible. Store away from other materials. Collect spillage.
6.4. Reference to other sections
See section 8. Exposure controls/personal protection
7.1. Precautions for safe handling
Handling : Wash thoroughly after handling.
Do not eat, drink or smoke when using this product.
Wash thoroughly after handling. Obtain special instructions before use.
Technical protective measures : Provide good ventilation in process area to prevent formation of vapour.
7.2. Conditions for safe storage, including any incompatibilities
Storage : Keep only in the original container in a cool, well ventilated place.
Keep container closed when not in use.
Storage - away from : Strong bases. Strong acids. Sources of ignition. Direct sunlight.
7.3. Specific end use(s)
Specific end use(s) : None.
8.1. Exposure controls Personal protection : Avoid all unnecessary exposure.
• Respiratory protection : Wear approved mask.
• Hand protection : Wear protective gloves.
• Skin protection : Wear suitable protective clothing.
• Eye protection : Chemical goggles or safety glasses.
• Others : When using, do not eat, drink or smoke.
8.2. Control parameters
Occupational Exposure Limits : No data available.
9.1. Information on basic physical and chemical properties
Physical state at 20 °C : Solid.
Odour threshold : No data available.
pH value : No data available.
Melting point [°C] : 108 - 112 °C
Decomposition point [°C] : N/A
Critical temperature [°C] : N/A
Auto-ignition temperature [°C] : N/A
Flammability (solid, gas) : N/A
Flash point [°C] : N/A
Boiling point [°C] : N/A
Initial boiling point [°C] : N/A
Final boiling point [°C] : N/A
Evaporation rate : N/A
Vapour pressure [20°C] : N/A
Vapour pressure mm/Hg : N/A
Vapour density : N/A
Density [g/cm3] : N/A
Relative density, gas (air=1) : N/A
Relative density, liquid (water=1) : N/A
Solubility in water [% weight] : Soluble in water
Solubility in water : N/A
Log Pow octanol / water at 20°C : No data available.
Solubility : 5.2
Viscosity at 40°C [mm2/s] : N/A
9.2. Other information
Explosive properties : N/A
Explosion limits - upper [%] : N/A
Explosion limits - lower [%] : N/A
Oxidising properties : No data available.
10.1. Reactivity
Reactivity : Not established.
10.2. Chemical stability
Chemical stability : Stable under recommended storage conditions.
10.3. Possibility of hazardous reactions
Hazardous reactions : Not established.
10.4. Conditions to avoid
Conditions to avoid : Direct sunlight. Extremely high or low temperatures.
10.5. Incompatible materials
Materials to avoid : Strong acids. Strong bases.
10.6. Hazardous decomposition products
Hazardous decomposition products : Fumes. Carbon monoxide. Carbon dioxide.
11.1. Information on toxicological effects Acute toxicity
• Inhalation : Based on available data, the classification criteria are not met.
• Dermal : Based on available data, the classification criteria are not met.
• Ingestion : Harmful if swallowed.
Corrosion : Based on available data, the classification criteria are not met.
Irritation : Causes serious eye irritation.
Causes skin irritation. Sensitization : Based on available data, the classification criteria are not met.
Mutagenicity : Based on available data, the classification criteria are not met.
Carcinogenicity : May cause cancer.
Toxic for reproduction : Based on available data, the classification criteria are not met.
STOT-single exposure : Based on available data, the classification criteria are not met.
STOT-repeated exposure : Based on available data, the classification criteria are not met.
Aspiration hazard : Based on available data, the classification criteria are not met.
12.1. Toxicity
Toxicity information : Harmful to aquatic life with long lasting effects.
12.2. Persistence - degradability
Persistence - degradability : May cause long-term adverse effects in the environment.
12.3. Bioaccumulative potential
Bioaccumulative potential : Not established.
12.4. Mobility in soil
Mobility in soil : Not established.
12.5. Results of PBT and vPvB assessment
Results of PBT and vPvB assessment : The substance does not
fulfil the criteria to be identified as PBT substance or vPvB substance
according to Annex XIII of Regulation REACH.
12.6. Other adverse effects
Environmental precautions : Avoid release to the environment.
13.1. Waste treatment methods
General : Avoid release to the environment.
Dispose in a safe manner in accordance with local/national regulations.
Dispose of this material and its container to hazardous or special waste
collection point, in accordance with local, regional, national and/or international regulation.
14.1. Land transport (ADR-RID)
General information : Not regulated.
14.2. Sea transport (IMDG) [English only]
General information : Not regulated.
14.3. Air transport (ICAO-IATA) [English only]
General information : Not regulated.
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
Safety, health and environmental : Ensure all national/local regulations are observed.
regulations/legislation specific for the substance or mixture
REACH Restrictions - Annex XVII : With the exception of those listed below: The components of this product are not subject to restrictions.
Annex XVII REACH Authorisation - Annex XIV : The components of this product are not subject to authorization.
15.2. Chemical Safety Assessment
Chemical Safety Assessment : It has not been carried out.
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic. vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL
of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 Further information : None. In accordance with REACH
Regulation (CE) Nº 1907/2006 and with CLP Regulation (CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
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