TOPFERS REAGENT SOLUTION

Substance / Preparation : Preparation.

Hazardous component(s) : This product is hazardous.

Substance name                                    Contents                                   CAS No             

DIMETHYL YELLOW (pH :                    > 0.01 < 1%                                 60-11-7               

INDICATOR) C.I.No.11020                                                                     

Phenolphthalein :                                     > 0.01 < 1%                                 77-09-8                 

Methanol :                                                 > 99 %                                       67-56-1 

3.1. Classification of the substance or mixture

Classification EC 67/548 or EC 1999/45

Classification : T; R23/24/25-R39/23/24/25

Hazard Class and Category Code(s), Regulation (EC) No 1272/2008

(CLP) Health hazards : Specific Target Organ

Toxicity - Single exposure - Category 1 - Danger (CLP : STOT SE 1) H370

Acute toxicity, dermal - Category 3 - Danger (CLP : Acute Tox. 3) H311

Acute toxicity, Inhalation - Category 3 - Danger (CLP : Acute Tox. 3) H331

Acute toxicity, Oral - Category 3 - Danger (CLP : Acute Tox. 3) H301

3.2. Label elements

Labelling EC 67/548 or EC 1999/45

Symbol(s) : T : Toxic   

R Phrase(s) : R23/24/25 : Toxic by inhalation, in contact with skin and if swallowed.

R39/23/24/25 : Toxic : danger of very serious irreversible effects

through inhalation, in contact with skin and if swallowed.

S Phrase(s) : S4 : Keep away from living quarters.

S24 : Avoid contact with skin.

S28 : After contact with skin, wash immediately with

S35 : This material and its container must be disposed of in a safe way.

S36/37 : Wear suitable protective clothing and gloves.

S38 : In case of insufficient ventilation, wear suitable respiratory equipment. 

S45 : In case of accident or if you feel unwell,

seek medical advice immediately (show the label when possible).

S59 : Refer to manufacturer/supplier for information on recovery/recycling.

Labelling Regulation EC 1272/2008 (CLP)

Hazard pictograms  

Signal words : Danger

Hazard statements : H301 : Toxic if swallowed.

H311 : Toxic in contact with skin.

H331 : Toxic if inhaled.

H370 : Causes damage to organ. Precautionary statements

• Prevention : P280: Wear protective gloves, protective clothing, eye protection, face protection.

P271: Use only outdoors or in a well-ventilated area.

P260: Do not breathe dust, fume, gas, mist, vapours, spray.

P264: Wash thoroughly after handling.

P270: Do not eat, drink or smoke when using this product.

• Response : P301+P310: IF SWALLOWED : Immediately call a POISON CENTER or doctor.

P307+P311: IF EXPOSED : Call a POISON CENTER or doctor.

P302+P352: IF ON SKIN : Wash with plenty of soap and water.

P304+P340: IF INHALED : Remove to fresh air and keep at rest in a position comfortable for breathing.

P363: Wash contaminated clothing before reuse.

P361: Remove immediately all contaminated clothing.

• Storage : P403+P233: Store in well-ventilated place. Keep container tightly closed.

P405: Store locked up.

• Disposal considerations : P501: Dispose of this material and its container to hazardous or

special waste collection point, in accordance with local, regional, national and/or international regulation.

P501: Dispose of this material and its container to hazardous or special waste collection point, in accordance

with local, regional, national and/or international regulation.

3.3. Other hazards

Other hazards : The substance does not fulfil the criteria to be identified as PBT

substance or vPvB substance according to Annex XIII of Regulation REACH. 

4.1. Description of first aid measures

Inhalation : Specific treatment (see on this label).

Remove to fresh air and keep at rest in a position comfortable for breathing.

Immediately call a POISON CENTER or doctor.

Skin contact : Remove affected clothing and wash all exposed skin area with mild soap and water, followed by warm water rinse.

Specific treatment (see on this label). Immediately call a POISON CENTER or doctor. Wash with plenty of soap and water.

Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse.

Eye contact : Obtain medical attention if pain, blinking or redness persist. Rinse cautiously with water for several minutes.

Remove contact lenses, if present and easy to do. Continue rinsing.

Ingestion : Rinse mouth. Do NOT induce vomiting.

Specific treatment (see on this label). Immediately call a POISON CENTER or doctor.

4.2. Most important symptoms and effects, both acute and delayed

Symptoms relating to use : Repeated exposure to this material can result in absorption through

skin causing significant health hazard. Causes damage to organ.

Danger of serious damage to health by prolonged exposure through inhalation.

Swallowing a small quantity of this material will result in serious health hazard.

4.3. Indication of any immediate medical attention and special treatment needed

General information : Never give anything by mouth to an unconscious person.

If you feel unwell, seek medical advice (show the label where possible).

Specific treatment (see on this label). Call a POISON CENTER or doctor. 

5.1. Extinguishing media

Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand.

Unsuitable extinguishing media : Do not use a heavy water stream.

 Surrounding fires : Use water spray or fog for cooling exposed containers.

5.2. Special hazards arising from the substance or mixture

Hazardous combustion products : Under fire conditions, hazardous fumes will be present.

5.3. Advice for fire-fighters

Protection against fire : Do not enter fire area without proper protective equipment,

including respiratory protection.

Special procedures : Exercise caution when fighting any chemical fire.

Avoid (reject) fire-fighting water to enter environment. 

6.1. Personal precautions, protective equipment and emergency procedures

For emergency responders : Equip cleanup crew with proper protection. Ventilate area.

Avoid breathing dust, fume, gas, mist, vapours, spray.

For non-emergency personnel : Evacuate unnecessary personnel.

6.2. Environmental precautions

Environmental precautions : Prevent entry to sewers and public waters.

Notify authorities if product enters sewers or public waters.

6.3. Methods and material for containment and cleaning up

Clean up methods : Soak up spills with inert solids, such as clay or diatomaceous

earth as soon as possible. Store away from other materials. Collect spillage.

6.4. Reference to other sections

See section 8. Exposure controls/personal protection 

9.1. Information on basic physical and chemical properties

Physical state at 20 °C : Liquid.

Odour threshold : No data available.

pH value : No data available.

Melting point [°C] : No data available.

Decomposition point [°C] : N/A

Critical temperature [°C] : No data available.

Auto-ignition temperature [°C] : No data available.

Flammability (solid, gas) : N/A 

Flash point [°C] : No data available.

Boiling point [°C] : N/A

Initial boiling point [°C] : No data available.

Final boiling point [°C] : No data available.

Evaporation rate : N/A

Vapour pressure [20°C] : No data available.

Vapour pressure mm/Hg : N/A

Vapour density : N/A

Density [g/cm3] : N/A

Relative density, gas (air=1) : N/A

Relative density, liquid (water=1) : N/A

Solubility in water [% weight] : N/A

Solubility in water : No data available.

Log Pow octanol / water at 20°C : No data available.

Solubility : N/A

Viscosity at 40°C [mm2/s] : No data available.

9.2. Other information

Explosive properties : N/A

Explosion limits - upper [%] : No data available.

Explosion limits - lower [%] : No data available.

Oxidising properties : No data available. 

11.1. Information on toxicological effects 

Toxicity information : The product has been not fully tested.

The calculated risk has been done under the requirements of the EU regulations.

Acute toxicity

• Inhalation : Toxic if inhaled.

• Dermal : Toxic in contact with skin.

• Ingestion : Toxic if swallowed.

Corrosion : Based on available data, the classification criteria are not met.

Irritation : Based on available data, the classification criteria are not met.

Sensitization : Based on available data, the classification criteria are not met.

Mutagenicity : Based on available data, the classification criteria are not met.

Carcinogenicity : Based on available data, the classification criteria are not met.

Toxic for reproduction : Based on available data, the classification criteria are not met.

STOT-single exposure : Causes damage to organ.

STOT-repeated exposure : Based on available data, the classification criteria are not met.

Aspiration hazard : Based on available data, the classification criteria are not met. 

12.1. Toxicity

Toxicity information : The product has been not fully tested.

The calculated risk has been done under the requirements of the EU regulations.

12.2. Persistence - degradability

Persistence - degradability : Biodegradable.

12.3. Bioaccumulative potential

Bioaccumulative potential : Not established.

12.4. Mobility in soil

Mobility in soil : Not established.

12.5. Results of PBT and vPvB assessment

Results of PBT and vPvB assessment : The substance does

not fulfil the criteria to be identified as PBT substance or vPvB

substance according to Annex XIII of Regulation REACH.

12.6. Other adverse effects

Environmental precautions : Avoid release to the environment. 

13.1. Waste treatment methods

General : Avoid release to the environment.

Dispose in a safe manner in accordance withlocal/national regulations.

Dispose of this material and its container to hazardous or special waste collection point,

in accordance with local, regional, national and/or international regulation.

Special precautions : Hazardous waste due to toxicity. 

15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture

Safety, health and environmental : Ensure all national/local regulations are observed.

regulations/legislation specific for the substance or mixture

REACH Restrictions - Annex XVII : With the exception of those listed

below: The components of this product are not subject to restrictions.

• Phenolphthalein : Annex XVII

REACH Authorisation - Annex XIV : The components of this product are not subject to authorization.

15.2. Chemical Safety Assessment

Chemical Safety Assessment : It has not been carried out. 

Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic. vPvB: very persistent and very bioaccumulative

Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL

of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives

67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 Further information : None. In accordance with REACH

Regulation (CE) Nº 1907/2006 and with CLP Regulation (CE) Nº 1272/2008 

DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.