TRYPSIN UG 2000
- Part number
- RXSOL-60-6605-790
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Trypsin is an enzyme that helps us digest protein. In the small intestine, trypsin breaks down proteins, continuing the process of digestion that began in the stomach. It may also be referred to as a proteolytic enzyme, or proteinase. Trypsin is produced by the pancreas in an inactive form called trypsinogen.
Applications
Trypsin is a serine protease that specifically cleaves at the carboxyl side of lysine and arginine residues. The selectivity of this enzyme is critical for reproducible protein digestion and mass spectrometry-based protein identification. Since chymotrypsin co-purifies with trypsin derived from natural sources, Pierce Trypsin Protease has been treated with TPCK to eliminate chymotryptic activity, improving digestion specificity. Native trypsin is also subject to autolysis which can reduce enzyme stability and efficiency. To reduce autolytic degradation, Pierce Trypsin Protease is chemically modified by methylation, yielding a highly active and more stable form of the enzyme.
Trypsin is a serine protease that specifically cleaves at the carboxyl side of lysine and arginine residues. The selectivity of this enzyme is critical for reproducible protein digestion and mass spectrometry-based protein identification. Since chymotrypsin co-purifies with trypsin derived from natural sources, Pierce Trypsin Protease has been treated with TPCK to eliminate chymotryptic activity, improving digestion specificity. Native trypsin is also subject to autolysis which can reduce enzyme stability and efficiency. To reduce autolytic degradation, Pierce Trypsin Protease is chemically modified by methylation, yielding a highly active and more stable form of the enzyme.
Dosage and directions
Take it 30 minutes before a meal or as directed by your doctor. Stop using Trypsin Chymotrypsin at least 2 weeks before a scheduled surgery as it may interfere with blood clotting. Inform your doctor if you have liver or kidney disease or problems with your blood clotting mechanism.
Characteristics and notes
Trypsin from the pyloric caeca of bigeye snapper was purified and characterized. Trypsin had an apparent molecular weight of 23.8 kDa when analyzed using sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and substrate-gel electrophoresis. The trypsin fraction consisted of three isoforms as evidenced by the appearance of three different bands on native-PAGE. Optimal activity was observed at 55C and pH range of 8–11.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | RXSOL-60-6605-790 |
| Product Type | TRYPSIN U/G 2000 |
| Revised date |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Stock Point : Mumbai, Kandla, Chennai, Visakhapatnam, Kolkata, Fujairah, Muscat Barka
| Phone | +91 22 27815541 / 42 |
| Fax | +91 22 2781 1318 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com |
3.1. Substance : TRYPSIN 2000 U/G
CAS No. : 9002-07-7
Substance.
Contains no other components or impurities which will influence the classification of the
product
3.1. Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Sensitisation — Respiratory, category 1 H334
Serious eye damage/eye H319
irritation, Category 2
Skin corrosion/irritation, H315
Category 2
Specific target organ
toxicity — Single
exposure, Category 3,
Respiratory tract irritation H335
Full text of classification categories and H statements : see section 16
Classification according to Directive 67/548/EEC or 1999/45/EC
R42
Xi; R36/37/38
Full text of R-phrases: see section 16
Adverse physicochemical, human health and environmental effects
No additional information available
3.2. Label elements
Labelling according to Regulation (EC) No. 1272/2008 [CLP]
Extra labelling to display Extra classification(s) to display
Symbol(s) : Xi : Irritation.
R Phrase(s):R36/37/38 Irritating to eyes, respiratory system and skin.
R42: May cause sensitization by inhalation.
S Phrase(s) :S22: Do not breath dust.
S24: Avoid contact with skin.
S26: In the case of contact with eyes, rinse immediately with plenty of water and seek
medical advise.
S36/37 : Wear suitable protective clothing and gloves.
Hazard pictograms
Signal word: Danger
Hazard statements : H315 - Causes skin irritation
H319 - Causes serious eye irritation
H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 - May cause respiratory irritation
Precautionary statements : P261 - Avoid breathing dust/fume/gas/mist/vapours/spray
P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing
P342+P311 - If experiencing respiratory symptoms: Call a POISON CENTER or
doctor/physician
3.3. Other hazards
No additional information available
4.1. Description of first aid measures
First-aid measures after inhalation : If breathing is difficult, remove victim to fresh air
and keep at rest in a position comfortable for breathing. If experiencing respiratory
symptoms: Call a POISON CENTER or doctor/physician.
Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a
POISON CENTER or doctor/physician if you feel unwell.
First-aid measures after skin contact : Wash with plenty of soap and water. Wash
contaminated clothing before reuse. If skin irritation occurs: Get medical
advice/attention. Specific treatment (see ... on this label).
First-aid measures after eye contact : Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation
persists: Get medical advice/attention.
First-aid measures after ingestion : Rinse mouth out with water. If you feel unwell, seek
medical advice.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms/injuries after inhalation : May cause respiratory irritation.
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Symptoms/injuries after skin contact : Causes skin irritation.
Symptoms/injuries after eye contact : Causes serious eye irritation.
4.3. Indication of any immediate medical attention and special treatment needed
Treat symptomatically
5.1. Extinguishing media
Suitable extinguishing media : dry chemical powder, alcohol-resistant foam, carbon
dioxide (CO2). Unsuitable extinguishing media : Do not use a heavy water stream.
5.2. Special hazards arising from the substance or mixture
No additional information available
5.3. Advice for firefighters
Protection during firefighting : Do not attempt to take action without suitable protective
equipment.
6.1. Personal precautions, protective equipment and emergency procedures
6.1.1. For non-emergency personnel
Emergency procedures : Evacuate unnecessary personnel.
6.1.2. For emergency responders
Protective equipment : Use personal protective equipment as required.
Emergency procedures : Stop release.
6.2. Environmental precautions Avoid release to the environment.
6.3. Methods and material for containment and cleaning up
Methods for cleaning up : Clear up rapidly by scoop or vacuum.
6.4. Reference to other sections
No additional information available
7.1. Precautions for safe handling
Precautions for safe handling : Avoid breathing dust/fume/gas/mist/vapours/spray. Use
only outdoors or in a wellventilated area.
Hygiene measures : Wash ... thoroughly after handling.
7.2. Conditions for safe storage, including any incompatibilities
Storage conditions : Keep container tightly closed. Store in original container. Store in a
dry place. Protect from moisture.
7.3. Specific end use(s)
No additional information available
8.1. Control parameters
No additional information available
8.2. Exposure controls
Hand protection : protective gloves
Eye protection : Chemical goggles or safety glasses
Skin and body protection : Wear suitable protective clothing
Respiratory protection : Wear respiratory protection
9.1. Information on basic physical and chemical properties
Odour threshold : No data available
pH : No data available
Relative evaporation rate (butylacetate=1) : No data available
Melting point : No data available
Freezing point : No data available
Boiling point : No data available
Flash point : No data available
Auto-ignition temperature : No data available
Decomposition temperature : No data available
Flammability (solid, gas) : No data available
Vapour pressure : No data available
Relative vapour density at 20 °C : No data available
Relative density : No data available
Solubility : Water: Soluble in water
Log Pow : No data available
Viscosity, kinematic : No data available
Viscosity, dynamic : No data available
Explosive properties : No data available
Oxidising properties : No data available
Explosive limits : No data available
9.2. Other information
No additional information available
10.1. Reactivity
No additional information available
10.2. Chemical stability
Stable under normal conditions.
10.3. Possibility of hazardous reactions
No additional information available
10.4. Conditions to avoid
Direct sunlight. Air contact. Moisture.
10.5. Incompatible materials
No additional information available
10.6. Hazardous decomposition products
No additional information available
11.1. Information on toxicological effects
Acute toxicity : Not classified
Skin corrosion/irritation : Causes skin irritation.
Serious eye damage/irritation : Causes serious eye irritation.
Respiratory or skin sensitisation : May cause allergy or asthma symptoms or breathing
difficulties if inhaled.
Germ cell mutagenicity : Not classified
Carcinogenicity : Not classified
Reproductive toxicity : Not classified
Specific target organ toxicity (single exposure) : May cause respiratory irritation.
Specific target organ toxicity (repeated exposure) : Not classified
Aspiration hazard : Not classified
12.1. Toxicity
No additional information available
12.2. Persistence and degradability
No additional information available
12.3. Bioaccumulative potential
No additional information available
12.4. Mobility in soil
No additional information available
12.5. Results of PBT and vPvB assessment
No additional information available
12.6. Other adverse effects
No additional information available
13.1. Waste treatment methods
Product/Packaging disposal Recommendations : Dispose of contents/container to ...
In accordance with ADR / RID / IMDG / IATA / ADN
14.1. UN number
UN-No. (ADR) : Not applicable
UN-No. (IMDG) : Not applicable
UN-No.(IATA) : Not applicable
UN-No.(ADN) : Not applicable
UN-No. (RID) : Not applicable
14.2. UN proper shipping name
Proper Shipping Name (ADR) : Not applicable
Proper Shipping Name (IMDG) : Not applicable
Proper Shipping Name (IATA) : Not applicable
Proper Shipping Name (ADN) : Not applicable
Proper Shipping Name (RID) : Not applicable
14.3. Transport hazard class(es)
ADR : Transport hazard class(es) (ADR) : Not applicable
IMDG : Transport hazard class(es) (IMDG) : Not applicable
IATA : Transport hazard class(es) (IATA) : Not applicable
AND : Transport hazard class(es) (ADN) : Not applicable
RID : Transport hazard class(es) (RID) : Not applicable
14.4. Packing group Packing group (ADR) : Not applicable
Packing group (IMDG) : Not applicable
Packing group (IATA) : Not applicable
Packing group (ADN) : Not applicable
Packing group (RID) : Not applicable
14.5. Environmental hazards
Dangerous for the environment : No
Marine pollutant : No Other information : No
supplementary information available
14.6. Special precautions for user
- Overland transport
No data available
- Transport by sea No data available
- Air transport No data available
- Inland waterway transport
No data available
-Rail transport
No data available
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable
15.1. Safety, health and environmental regulations/legislation specific for the
substance or mixture
15.1.1. EU-Regulations
No REACH Annex XVII restrictions
TRYPSIN 2000 U/G Extra Pure is not on the REACH Candidate List
TRYPSIN 2000 U/G Extra Pure is not on the REACH Annex XIV List
15.1.2. National regulations
Germany
12th Ordinance Implementing the Federal
Immission Control Act - 12.BImSchV: Is not subject of the 12. BlmSchV (Hazardous
Incident Ordinance)
Denmark
Recommendations Danish Regulation : Young people below the age of 18 years are not
allowed to use the product
15.2. Chemical safety assessment
No additional information available
Abbreviations and acronyms : PBT: persistent, bioaccumulative and toxic.
vPvB: very persistent and very bioaccumulative
Sources of key data used : REGULATION (EC) No 1272/2008 OF THE EUROPEAN
PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification,
labelling and packaging of substances and mixtures, amending and repealing Directives
67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006
Further information : None.
In accordance with REACH Regulation (CE) Nº 1907/2006 and with CLP Regulation
(CE) Nº 1272/2008
DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable.
Availability
TRYPSIN UG 2000 manufacturers, suppliers, exporters in Mumbai, Gandhidham, Kolkata, Varanasi, Visakhapatnam, Chennai, Fujairah, Dubai, Canada BC, Barka, Sohar, Muscat, Oman.
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TRYPSIN UG 2000 is available in small packing as well as in bulk. Buy premium quality TRYPSIN UG 2000 and other lab chemicals from one of the most trusted brands.
