TYRAMINE
- Part number
- RXSOL-60-6605-799
- Category
- Lab Chemical
- Brand
- RXSOL
Overview
Tyramine is found in foods that have gone bad or in foods or drinks that were made by fermenting bacteria, like beer, cheese, and tofu. Some dietary supplements contain tyramine. Tyramine is used for weight loss and athletic performance, but there is no good scientific evidence to support these uses.
Applications
Tyramine (TIE-ruh-meen) is an amino acid that helps regulate blood pressure. It occurs naturally in the body, and it's found in certain foods. Medications called monoamine oxidase inhibitors (MAOIs) block monoamine oxidase, which is an enzyme that breaks down excess tyramine in the body.
Dosage and directions
Meals that contain no more than 600 mg of tyramine are considered safe for most people. However, eating a meal that contains more than 600 mg of tyramine is POSSIBLY UNSAFE. This amount of tyramine might increase the risk for adverse effects, including high blood pressure and headache
Characteristics and notes
Tyramine (also spelled tyramin), also known under several other names, is a naturally occurring trace amine derived from the amino acid tyrosine.
Safety and SDS
Read the safety data sheet before handling. Wear suitable gloves and eye protection.
View safety data sheet
| Product Name | TYRAMINE |
| Part Number | RXSOL-60-6605-799 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA
| Phone | +91 22 20871200 - 1400 |
| Fax | +91 22 27612100 :::AOH :0091 9821214367 |
| rxsolchemicals@gmail.com | |
| Website | www.rxmarine.com |
| Chemical Name | CAS | EC number | Weight |
|
2-(4-Hydroxyphenyl)ethylamine 4-(2-Aminoethyl)phenol 4-Hydroxyphenethylamine |
51-67-2 | 200-115-8 | 137,18 g/mol |
| Signal Word | Warning |
| Hazard Statements |
H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation |
| P280 Wear protective gloves.P305 + P351 + P338 | Wear eye protection/ face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Precautionary statements - response | P261 Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Response | None |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
| Prevention | P273 Avoid release to the environment. |
| Supplemental Hazard Statements | None |
| Other hazards | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| General advice | Show this material safety data sheet to the doctor in attendance. |
| If inhaled | After inhalation: fresh air. |
| Eye Contact | After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses. |
| Swallowed | After swallowing: immediately make victim drink water (two glasses at most). Consult a physician |
| Skin Contact | In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. |
| Inhalation | Move to fresh air. If breathing is difficult, give oxygen. Get medical attention immediately if symptoms occur. |
| Ingestion | Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately. |
| Notes to Physician | Treat symptomatically |
| Most important symptoms and effects, both acute and delaye | The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 |
| Indication of any immediate medical attention and special treatment needed | No data available |
| Flammability | May be combustible at high temperature. |
| Flash Point | CLOSED CUP: Higher than 93.3°C (200°F). |
| Suitable extinguishing media | Water Foam Carbon dioxide (CO2) Dry powder |
| Unsuitable extinguishing media | For this substance/mixture no limitations of extinguishing agents are given. |
| Special hazards arising from the substance or mixture | Carbon oxides Nitrogen oxides (NOx) |
| Further information | Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system |
|
Hazardous combustion products |
Fire may cause the evolution of Sulphur oxides, nitrogen oxides. |
| Advice for firefighters | Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing. |
| Protective Equipment | Use personal protective equipment. |
| Specific Hazards Arising from the Chemical |
Has a fire-promoting effect due to the release of oxygen. Ambient fire may liberate hazardous vapours. |
| Personal precautions, protective equipment and emergency procedures | Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. |
| Spillage | Oxidizing material. Stop leak if without risk. Avoid contact with a combustible material (wood, paper, oil, clothing...). Keep substance damp using water spray. Do not touch spilled material. Prevent entry into sewers, basements or confined areas dike if needed. Eliminate all ignition sources. Call for assistance on disposal. |
| Personal Protection | Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: Protective equipment see section 8. |
| Enviromental Precaution | Do not let product enter drains. |
|
Methods and materials for containment and cleaning |
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts. |
| Advice on safe handling | Work under hood. Do not inhale substance/mixture. |
| Advice on protection against fire and explosion | Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge |
| Hygiene measures | Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance. For precautions |
| Precautions for safe handling | For precautions see section 2.2 |
| Conditions for safe storage, including any incompatibilities | Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials. |
| Storage conditions | Tightly closed. Dry |
| Storage class | Storage class (TRGS 510): 11: Combustible Solids |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Handling | Keep away from heat. Keep away from sources of ignition. Keep away from combustible material.. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as reducing agents, combustible materials, organic materials, metals |
| Advice on general occupational hygiene | Advice on safe handling Observe label precautions. Change contaminated clothing. Wash hands after working with substance. |
| Occupational Exposure limit values | No data available |
| Biological limi values | No data available |
| Exposure controls | Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the riskelimination area |
| Engineering Control | Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. |
| Eye/face protection | Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses |
| Body Protection | protective clothing |
| Skin protection | Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. |
| Respiratory protection | required when dusts are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system. Recommended Filter type: Filter type P2 The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented. |
| Other Protection Measure | Handle in accordance with good industrial hygiene and safety practice. |
| Control of environmental exposure | Do not let product enter drains. |
| Thermal hazards | No data available |
Gloves Suit
| Physical state | Powder |
| Colour | Beige |
| Odour | No data available |
| Odor Threshold | Not Applicable |
| pH | Not Applicable |
| Melting Point | 160 - 162 °C - lit. |
| Boiling Point | 175 - 181 °C at 10 hPa - lit. |
| Flash Point | No data available |
| Evaporation Rate | Not Applicable |
| Flammability (solid, gas) | No data available |
| Explosive limits | No Data Available |
| Upper/lower flammability or explosive limits | No data available |
| Autoignition temperature | No data available |
| Decomposition temperature | No data available |
| Vapour pressure | No Data Available |
| Density | No data available |
| Vapour Density | No Data Available |
| Specific Gravity | No data available |
| Partition coefficient | No data available |
| Explosive properties | None |
| Solubility | DMSO (Slightly), Water (Slightly) |
| Ignition temperature | No information available. |
| Particle characteristics | No data available |
| Reactivity | No data available |
| Stability | No data available |
| Possibility of hazardous reactions | No data available |
| Conditions to avoid | No data available |
| Incompatible materials | 175 - 181 °C at 10 hPa - lit. |
| Hazardous Polymerization | No data available |
| Acute toxicity | No data available Inhalation: No data available Dermal: No data available |
| Skin corrosion/irritation | Remarks: No data available |
| Serious eye damage/eye irritation | No data available |
| Respiratory or skin sensitization | No data available |
| Serious eye damage/eye irritation | No data available |
| Rout Of Entry | Inhalation. Ingestion. |
| Toxicity to Animal | WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE Acute oral toxicity (LD50): 689 mg/kg [Rat]. |
| Toxic Effects on Human | May cause damage to the following organs: upper respiratory tract. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lung irritant, lung sensitizer). |
| Germ cell mutagenicity | Laboratory experiments have shown mutagenic effects. Species: Rat Application Route: Intraperitoneal Remarks: Cytogenetic analysis Species: Mouse Application Route: Intraperitoneal Remarks: Micronucleus test |
| Reproductive toxicity | No data available |
| Specific target organ toxicity - single exposure | Inhalation - May cause respiratory irritation |
| Special Remarks on other Toxi Effects on Humans: |
Acute Potential Health Effects: Skin: Causes skin irritation. May cause skin sensitization, an allergic reation, which becomes evident upon re-exposure to this material. Eyes: Causes eye irritation. Ingestion: Causes gastrointestinal (digestive) tract irritation with nausea, vomiting, and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May cause chemical pneumonitis and pulmonary edema, inflammation, edema of bronchi and larynx. Chronic Potential Health Effects: Repeated or prolonged skin exposure may cause allergic reactions in sensitive individuals. Repeated or prolonged exposure by inhalation may affect respiration and metabolism. |
| Additional Information | Endocrine disrupting properties |
| Assessment | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. RTECS: DK2625000 burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, Damage to the eyes. To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Stomach - Irregularities - Based on Human Evidenc |
| Persistence and degradability | No data available |
| Toxicity | No data available |
| Bioaccumulative potential | No data available |
| Toxicity to fish | Flow-through test LC50 - Oryzias latipes - > 95,4 mg/l - 96 h (OECD Test Guideline 203) |
| Toxicity to daphnia and other aquatic invertebrates | Static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h (OECD Test Guideline 202) |
| Toxicity to algae | Static test ErC50 - SELENASTRUM - > 998 mg/l - 72 h (OECD Test Guideline 201) |
| Eco Toxicity | Not Available |
| COD and BOD 5 | Not Available |
| Products Biodegradation: | The methods for determining the biological degradability are not applicable to inorganic substances. |
| Mobility in soil | No Information available |
| Results of PBT and vPvB assessment | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Endocrine disrupting properties | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher |
| Assessment | The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.. |
| Other adverse effects | No data available |
| Disposal methods | The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems. |
| Contaminated packaging | Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials. |
| Waste treatment Method | No data available |
| UN number |
ADR/RID: IMDG: IATA: |
|
| UN number | ADR/RID: IMDG: IATA: | |
| UN proper shipping name | ADR/RID: IMDG: IATA: | |
| Transport hazard class(es) | ADR/RID: IMDG: IATA: | |
| Packaging group | ADR/RID: IMDG: IATA: | |
| Environmental hazards | ADR/RID: No IMDG: No IATA: No | |
| Special precautions for user | No data available | |
| Further information | Not classified as dangerous in the meaning of transport regulations. | |
| Transport in bulk according to IMOinstruments | No data available |
| Safety, health and environmental regulations/legislation specific for the substance or mixture | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. |
| Safety, health and environmental regulations specific for the product in question | European Inventory of Existing Commercial Chemical Substances (EINECS) -Listed.EC Inventory Listed. United States Toxic Substances Control Act (TSCA) Inventory- Listed. China Catalog of Hazardous chemicals 2015 Not- Listed. New Zealand Inventory of Chemicals (NZIoC)Listed. PICCS -Listed. Vietnam National Chemical Inventory -Listed. IECSC Listed. Korea Existing Chemicals List (KECL) -Listed. |
| National legislation | Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances. : ACUTE TOXIC : ENVIRONMENTAL HAZARDS |
| DSCL (EEC) | R8- Contact with combustible material may cause fire. R20/22- Harmful by inhalation and if swallowed. R36/37/38- Irritating to eyes, respiratory system and skin. R42/43- May cause sensitization by inhalation and skin contact. S22- Do not breathe dust. S24- Avoid contact with skin. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37- Wear suitable gloves. |
| Other regulations | Take note of Dir 94/33/EC on the protection of young people at work. |
| Chemical Safety Assessment | For this product a chemical safety assessment was not carried out |
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
|
ADR/RID: IMDG: IATA: |
|
ADR/RID: IMDG: IATA: |
|
ADR/RID: IMDG: IATA: |
|
ADR/RID: IMDG: IATA: |
