Overview
Hexamine also referred to as Hexamethylenetetramine, Methenamine, or Urotropin. Hexamine or urotropin, is a heterocyclic organic compound with the formula C6H12N4 .It appears as white crystalline compound and it is highly soluble in water and polar organic solvents. It has a cage-like structure similar to adamantane. It is useful in the synthesis of other chemical compounds, e.g., plastics, pharmaceuticals, rubber additives.
Technical specifications
| Hexamine can be described as a heterocyclic organic compound having the chemical formula C6H12N4 |
General Information
| CAS Number | 100 - 97 - |
|---|---|
| EINECS Number | - 905 - 8 |
| Chemical Name | Hexamethylene tetramine |
| Chemical Classification | Amine / Cyclic amine |
Synonyms
| Methenamine, HMT, HMTA, Hexamine, 1,3,5,7-tetraaza adamantane, Hexamethylenamine, Aminoform, Ammoform, Cystamin, Cystogen, Formin, Uritone, Urotropin | |
| Formula | C6H12N4 |
|---|---|
| Molecular weight | 140.19 |
| Shipping Name | Hexamine |
| Codes / Label | Flammable solid, class - 4.1 |
| Hazardous Waste ID No | Not applicable |
| Hazchem Code | Not applicable |
| UN Number | 1328 |
| Description | White crystalline odorless solid |
Applications
Unstabilized: In adhesives, coatings and sealing compounds, in the preservation of hides, as cross-linking agent for hardening phenol-formaldehyde resins & vulcanizing rubber, as corrosion inhibitor for steal, as dye fixative, as fuel tablets for camping stoves, as stabilizer for lubricating and insulating oils, for manufacture of explosives, chemical detection of metals, as an urinary antiseptic.
Stabilized:In process industry, as per the requirements of specific customers.
Uses:
- It can be used as a curing agent for resins and plastics, the vulcunization accelrator of rubber and textile shrink proof agent.
- It can also be used for making antimicrobial drug explosives and so on. As medicine, after oral administration, It can be decomposed when coming accros acidic urine to generate formaldehye and exerts its antibacterial effect used for treating mild urinary tract infection; it can be extremely used for treating ringworm, antiperspirants, and treatment of undrarm odor. Its beingmixed with caustic soda sodium phenol can be used as the phosgene absorber of gas masks. It can be used as a kind of anti-microbial agent.
- It can be used as antishrinking textile finishing agent, bleaching agent of sodium chlorite and the buffer of waterproffing agent
- Hexamethylenetetramine is mainly used as the curing agent of plastic and resin, the catylist and foaming agent of aminoplast, rubber vulcunization accelerator and the shrink proof agent of textiles.
- Hexamethylene tetramine is raw material of organic synthesis and can be used for the production of chloramphenicol in the pharmaceutical industry.
- Hexamethylenetetramine can be used as the disinfectant of urinary system with itself having no antibacterial effect and being effectice in treating gram-negative bacteria. Its 20% solution can be used for the treatment of underam odour, sweaty feet tinea and so on.Its being mixed with sodium phenol and can be used as phosegen absorber for gas masks. It can also be used for the manufacture of pesticide.
- Hexamethylenetetramine can be used as reagent and chromatographic reagent for determination of bismuth,indium, mangnase, cobalt, thorium, platinum, producing magnessium,lithium, copper, uranium, beryllium, tellurium, bromide, and iodide.In the liver function tests, it can be used for formulating thymol turbidity, test and measurement of object such as bismuth, iron, manganese, cobalt, thorium, platinum and magnesium as well as the determination and identification of lithium, iron cyanide, iron bromide and iodide. It can also be used for the determination of copper, uranium, beryllium, tellurium etc. Moreover, it can be used as gas chromatography fixed solution (maximum usage temperature of 180 ℃ with the solvent being chloroform).
Hexamine Uses (C6H12N4)
.Hexamine is used in the production of liquid or powdery preparations of phenolic resins.
.Used as binders in clutch and brake linings.
.Used in the form of spray and cream to treat concomitant odour and excessive sweating.
.Used in Grocott’s methenamine silver stain.
.Used as a solid fuel.
.Used as a food preservative.
.Used as a primary ingredient in making RDX.
.Used to prevent vulcanized rubber.
.Used as a corrosion inhibitor for steel.Hexamine Uses (C6H12N4)
.Hexamine is used in the production of liquid or powdery preparations of phenolic resins.
.Used as binders in clutch and brake linings.
.Used in the form of spray and cream to treat concomitant odour and excessive sweating.
.Used in Grocott’s methenamine silver stain.
.Used as a solid fuel.
.Used as a food preservative.
.Used as a primary ingredient in making RDX.
.Used to prevent vulcanized rubber.
.Used as a corrosion inhibitor for steel.
Characteristics and notes
MEDICINAL USE OF HEXAMINE
HEXAMINE acts as an anti-infective agent, which is the most commonly used element to treat urinary tract infections. The anti-infective action of hexamine is derived from the slow release of formaldehyde (CH2O) by the process of hydrolysis at an acidic pH of 0.2 molars. Also, methenamine is a colorless, odorless, and lustrous crystal or white hygroscopic crystalline powder.
HEXAMINE acts as an anti-infective agent, which is the most commonly used element to treat urinary tract infections. The anti-infective action of hexamine is derived from the slow release of formaldehyde (CH2O) by the process of hydrolysis at an acidic pH of 0.2 molars. Also, methenamine is a colorless, odorless, and lustrous crystal or white hygroscopic crystalline powder.
Since the mandelic acid salt (which is a generic methenamine mandelate, USP) is used for urinary tract infection treatments, it decomposes at an acidic pH to produce ammonia, and formaldehyde is bactericidal; which the mandelic acid adds to this effect. Typically, urinary acidity is ensured by co-administering ammonium chloride or vitamin C (otherwise an ascorbic acid).
This compound's usage had temporarily been reduced in the late 1990s because of the adverse effects, specifically chemically-induced hemorrhagic cystitis in the case of overdose. However, currently, its use has been re-approved due to the prevalence of antibiotic resistance to drugs, which are more commonly used. This drug is especially suitable for long-term prophylactic urinary tract infection treatments because the bacteria do not develop resistance to formaldehyde. Also, it should not be used in chronic kidney disease presence.
In the form of spray and creams, hexamine is successfully used for the treatment of concomitant odor and excessive sweating with the medical citation.
Availability
HEXAMINE White Crystal exporter and supplier in Mumbai Maharastra, Varanasi UP Uttar Pradesh, Surat Gandhidham Gujrat, Chennai Tamil Nadu, Visakhapatnam Andhra Pradesh, Kolkata West Bengal.
